Nervous System Diseases

1,005 trials 421 recruiting

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Management of Parkinson's disease if levodopa is broken down prematurely Recruiting

2024-510629-24-00 Parkinson's disease 4 2025-05-14
Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy Recruiting

2024-514689-38-01 Pain Associated With Diabetic Peripheral Neuropathy 4 2025-05-12
The FibroCAN study Recruiting

2024-516597-30-00 Diabetic cardiovascular autonomic neuropathy 4 2025-05-02
Clinical trial to compare the effectiveness of migraine’s preventive treatments in primary care Recruiting

2024-513597-22-00 Migraine 6 2025-04-29
Evaluation of the safety of a strategy combining etanercept administration with repeated contrast ultrasound in patients with Alzheimer's d… Recruiting

2023-505714-19-00 Alzheimer's disease 3 2025-04-16
StAtins in Frail oldEr patients with ischemic Stroke or Transient ischemic attack – The Randomized Controlled Trial Recruiting

2024-517343-31-00 Ischemic stroke and transient ischemic attack 6 2025-04-11
A Study to Evaluate the Efficacy, Safety and Tolerability of ALN-APP in Patients with Cerebral Amyloid Angiopathy (CAA) Recruiting

2023-510137-29-01 Cerebral Amyloid Angiopathy (CAA) is a neurological con 4 2025-04-09
A Phase 3, Parallel Group Study to Evaluate KarXT as a Treatment for Psychosis Associated with Alzheimer’s Disease Recruiting

2024-516363-92-00 Psychosis Associated with Alzheimer’s Disease 5 2025-04-08
Efficacy and tolerability of efgartigimod as early treatment in patients with generalized myasthenia gravis. Recruiting

2024-516015-24-00 Patients affected by generalized myasthenia gravis 6 2025-04-07
A Multicenter, Randomized, Double-masked, Placebo-controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacod… Recruiting

2024-517957-29-00 Mild Cognitive Impairment (MCI) 4 2025-04-02
Efficacy and safety of minidosing lysergic acid diethylamide (LSD) for chronic cluster headache: a randomized placebo-controlled study Recruiting

2024-520305-39-00 Chronic cluster headache 4 2025-04-01
A clinical proof-of-concept study to reduce smoldering inflammation in progressive MS Recruiting

2024-517336-21-00 Progressive multiple sclerosis 4 2025-03-31
Clear-Brain: stimulating amyloid clearance in cerebral amyloid angiopathy Recruiting

2023-506128-10-00 Cerebral amyloid angiopathy 4 2025-03-27
Folinic acid therapy in patients with Kearns-Sayre syndrome (KSS) and cerebral folate deficiency - mitoFolat Recruiting

2023-503730-45-00 Kearns-Sayre-Syndrom 4 2025-03-21
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant Recruiting

2024-513547-82-00 Transthyretin Amyloidosis 5 2025-03-11
Thrombolysis in Factor Xa-inhibitors Trial (SIFT) Recruiting

2023-509907-34-01 acute ischemic stroke 5 2025-03-10
A Study to Evaluate ALN-HTT02 in Adult Patients with Huntington’s Disease Recruiting

2024-515732-68-00 Huntington’s disease 1 2025-03-07
MAESTRO-4MS : "Allogenic Adipose tissue-derived Mesenchymal Stromal Cells for the treatment of Primary Progressive Multiple Sclerosis: an op… Recruiting

2023-509538-20-01 Primary Progressive Multiple Sclerosis 1 2025-03-06
Phase 1 study to evaluate [18F]ACI-15916 as a potential PET radioligand for imaging α-synuclein deposits in the brain of patients with suspe… Recruiting

2024-515664-31-00 Parkinson's Disease 1 2025-03-04
Boosting recovery through excitation of arousal and awareness in comatose patients: Dose finding study (BREA2KTHROUGH DOSEFINDER) Recruiting

2023-503617-30-02 Coma and other disorders of consciousness due to acute 3 2025-02-26
STROKE-POC Recruiting

2024-510866-18-00 Spasticity after Stroke 4 2025-02-21
Study of ARO-DUX4 in Adult Patients With Facioscapulohumeral Muscular Dystrophy Type 1 Recruiting

2023-509748-89-00 Facioscapulohumeral muscular dystrophy (FSHD) 7 2025-02-19
Hypertonic lactate after cardiac arrest Recruiting

2023-506031-15-01 post-anoxic brain injury 4 2025-02-18
An open single-center, phase I proof of concept trial to assess the safety and feasibility of adoptive cell therapy with autologous EBV-spec… Recruiting

2024-515563-55-00 Multiple sclerosis 3 2025-02-17