Nervous System Diseases

1,027 trials 418 recruiting

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Estudio enmascarado, controlado con placebo, aleatorizado, piloto, de ApTOLL para el tratamiento de pacientes con ictus isquémico agudo a ni… Not authorised

2023-504015-32-00 Acute Ischemic Stroke (AIS) 4
PRObiotic Therapy Examining Combinatorial Therapeutics in Multiple Sclerosis - phase II, multicenter, randomised, open-label clinical trial. Not authorised

2025-520955-10-00 Multiple sclerosis 4
Boosting recovery through excitation of arousal and awareness in comatose patients (BREA2KTHROUGH) Not authorised

2023-503617-30-01 Coma and other disorders of consciousness due to acute 9
A study to investigate long-term safety and tolerability of tolebrutinib in participants with multiple sclerosis Not authorised

2023-503631-18-00 Nervous system diseases 5
Maintenance Therapy of the Effects of Donepezil-iGaLa Combined Therapy in Post-Stroke Chronic Aphasia: Identification of Predictive Biomarke… Not authorised

2024-518763-35-00 Chronic post-stroke aphasia. 5
Investigating a New Treatment: Clinical Study on Coenzyme Q (Ubiquinol) for Patients with Mitochondrial Disorders and Cerebellar Ataxias Not authorised

2023-505244-18-01 Mitochondrial disorders and/or cerebellar ataxias 4
An Open-label Phase 2b Study with Blinded Evaluation of the Combination of Amodiaquine and Potassium Canrenoate with Exenatide or Glibenclam… Not authorised

2025-522796-28-00 Acute Ischemic Stroke 4
Atorvastatin in episodic migraine Not authorised

2022-502176-23-00 Migraine 4
Atorvastatin in chronic migraine (StainMigChronic) Not authorised

2022-502177-42-01 Chronic migraine 4
A Phase 1/2 Clinical Study of Intravenous Gene Transfer with an AAVrh10 Vector Expressing GALC in Krabbe Subjects Receiving Hematopoietic St… Not authorised

2023-504900-28-00 Krabbe Disease 7
A Phase IIa, Open Label Study to Evaluate the Safety of Afamelanotide in Patients with Early Parkinson's Disease Not authorised

2022-502207-30-00 Parkinson's Disease 4
Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Not authorised

2024-514411-95-00 Amnestic mild cognitive impairment (aMCI, single or mul 4
A phase 1, randomized, double-blind, placebo-controlled study investigating the safety, tolerability, pharmacokinetics, and pharmacodynamics… Not authorised

2024-512106-26-00 Cognitive impairment 1
A Randomized, Placebo-controlled, Double-blind, Parallel group, 6 Month Study to Evaluate the Safety, Tolerability, and Potential Efficacy o… Not authorised

2022-500828-30-00 Early Alzheimer´s Disease 4
A study to find how well LY3884961 works and how safe it is in participants with Parkinson’s disease Not authorised

2024-519587-40-00 Parkinson’s Disease with at Least One GBA1 Mutation 7
A Study to Assess if BIIB080 Can Change Clinical Dementia Rating-Sum of Boxes Scores, and BIIB080 Safety and Tolerability When Injected Into… Not authorised

2022-501644-15-00 Mild Cognitive Impairment due to Alzheimer's Disease Al 4
A Study Providing Continued Access to Treatment in Patients with a Neurological Disease Previously Enrolled in a Genentech and/or F. Hoffman… Not authorised

2023-507633-21-00 Neurological Disease 5
First administration in healthy volunteers of a single and increasing dose of a new molecule for the treatment of brain diseases Not authorised

2023-505030-99-00 Post-Traumatic Stress Disorder (PTSD) 1
GRoningen Early-PD Ambroxol Treatment Pharmacokinetics Pending

2024-519088-16-01 Parkinson's disease 3
Efficacy and safety of a combined therapy in the symptomatic treatment of diabetic sensorimotor polyneuropathy - a prospective, randomized, … Pending

2025-521985-82-00 Diabetic sensorimotor polyneuropathy (DSPN) 4
CACH RECEVA: Calcium Channel blocker in treatment of reversible cerebral vasoconstriction syndrome: a double-blind, randomized, placebo-cont… Pending

2023-504547-14-01 Reversible cerebral vasoconstriction syndrome 6
APICALE - Cervical facet injection of corticosteroids for the management of cervicobrachialgia : protocol for a randomized pilot study Pending

2024-511790-30-00 Cervicobrachial Neuralgia 5
Hydroxychloroquine in progressive MS Pending

2025-522573-11-00 Multiple Sclerosis 4
FIDES: Focused Ultrasound-mediated Blood-Brain Barrier Opening In Pontine Diffuse Midline Glioma (DMG) to Enhance Systemic Therapy with Temo… Pending

2025-520814-78-00 Diffuse Midline Glioma, H3K27-altered 9