Nervous System Diseases

1,005 trials 421 recruiting

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Impact of CHOlinergic Stimulation on COgnitive and MOtor Functions and Brain Activity in Elderly Volunteers (CHOCOMO) - a randomised, placeb… Recruiting

2024-512172-35-00 neurological disorders 4 2025-02-17
Ozone treatment in patients with numbness and/or tingling secondary to chemotherapy. Randomized clinical trial. Recruiting

2024-517196-20-00 Paresthesia (numbness, tingling) secondary to chemother 10 2025-02-07
A randomized phase III trial with lomustine versus lomustine and bevacizumab for patients with recurrent glioblastoma Recruiting

2024-519437-27-02 Glioblastoma 5 2025-02-03
DISEASE MODIFYING THERAPIES WITHDRAWAL IN INACTIVE RELAPSING-REMITTING MULTIPLE SCLEROSIS PATIENTS AGED 55 AND OVER: A MULTICENTRIC, RANDOMI… Recruiting

2024-513475-41-00 Multiple Sclerosis 5 2025-02-03
A Multi-centered, Double-blind, Randomized, Placebo-controlled Study of TEV-56286 for the Treatment of Multiple System Atrophy Recruiting

2023-505320-54-00 Multiple System Atrophy 4 2025-01-30
Water absorption in brain of hydrocephalus Recruiting

2024-519933-53-00 Adult hydrocephalus 5 2025-01-29
Intrathecal MRI Contrast for Assessment of CSF Transport Recruiting

2024-519936-18-00 CSF disorders 6 2025-01-29
Use of stem cells for the treatment of traumatic brain injury. Multicenter, doubleblind, randomized with placebo phase II clinical trial. Recruiting

2024-516510-38-00 Traumatic Brain Injury 4 2025-01-27
Phase I, open-label clinical trial to evaluate the safety and clinical response of repeated-dose intra-arterial infusion of autologous mesen… Recruiting

2024-520427-86-00 Autoimmune refractory epilepsy and Rasmussen Encephalit 1 2025-01-24
EFFICACY OF SUPRASPINATUS NERVE APPROACH THROUGH CORTICOSTEROID ADMINISTRATION VERSUS PULSED RADIOFREQUENCY IN CHRONIC SHOULDER PAIN. DOUBLE… Recruiting

2024-519892-24-00 Chronic shoulder pain 5 2025-01-15
Deferoxamine in Aneurysmal Subarachnoid Hemorrhage trial Recruiting

2024-514615-10-01 Subarachnoid hemorrhage 9 2025-01-14
Treatment of acute ischemic stroke due to occlusion of a large vessel by mechanical thrombectomy in patients with unknown onset or not meeti… Recruiting

2024-515062-13-00 acute ischemic stroke caused by occlusion of a large ve 5 2025-01-14
MRI contrast agent in the spinal canal to investigate transportation of the cerebrospinal fluid in the brain. Recruiting

2024-520146-33-00 Cerebrospinal fluid circulation disorder seen in clinic 9 2025-01-13
Safety and efficacy of botulinum toxin A in patients with posttraumatic headache: a double-blind, randomized, placebo-controlled, parallel-g… Recruiting

2024-515901-24-00 Persistent post-traumatic headache 5 2025-01-10
Early immunotherapy with intravenous immunoglobulin, cyclophosphamide and methylprednisolone in patients with anti-Hu-associated paraneoplas… Recruiting

2023-506942-22-01 paraneoplastic sensory neuropathy with anti-Hu antibodi 4 2025-01-10
Quantification tools for a novel tau PET marker in a rare neurological disease: 18F-PI-2620 in progressive supranuclear palsy Recruiting

2023-508718-40-00 Progressive supranuclear palsy 4 2025-01-09
Phase III trial of lomustine/temozolomide (TMZ) combination therapy vs. standard TMZ therapy for newly diagnosed MGMT promoter methylated gl… Recruiting

2023-506998-35-00 Glioblastoma 5 2025-01-08
APEDOC: The role of peripheral afferents in modulating post-stroke central pain Recruiting

2023-504676-17-00 Patients with central neuropathic pain POST stroke 5 2025-01-06
Studying the effects of deferiprone in Pelizaeus-Merzbacher disease Recruiting

2024-511968-81-00 Pelizaeus-Merzbacher disease 4 2024-12-27
Factors Determining the Efficacy of Botulinum Toxin for Arm Tremor in Dystonia: An Exploratory Study Recruiting

2024-515970-28-00 Dystonic tremor syndrome 6 2024-12-20
A study to determine if BHV-7000 is safe in adults with refractory focal onset epilepsy Recruiting

2023-508813-18-00 Refractory Focal Onset Epilepsy 4 2024-12-18
A first-in-human (FIH) clinical trial to investigate the human monoclonal antibody NG004, administrated intrathecally in acute spinal cord i… Recruiting

2024-514303-34-00 Acute Incomplete Cervical Spinal Cord Injury 1 2024-12-18
A Phase-2b, Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Activity and Safety of Inebilizumab in Anti-NMDA Receptor Enc… Recruiting

2023-504686-23-00 anti-N-methyl-D-aspartate receptor encephalitis (anti-N 4 2024-12-10
A Study to Assess Distribution, Binding, and Retention of the Monoclonal Antibody Trontinemab in the Brain of Healthy Participants and Patie… Recruiting

2023-509900-14-00 Alzheimer’s Disease (AD) 3 2024-12-10