Immune System Diseases

926 trials 377 recruiting

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Ultimate dePletion of autoReactive b cells using Obinutuzumab from sjÖgren's syndrome affected Tissues study- UPROOT study Pending

2024-519884-16-00 Sjögren's syndrome 4
Supporting weak immune system during autoimmune therapy: testing Panzyga to prevent infections Pending

2025-522854-37-00 Prevention of a Major infection in patients with Hypoga 5
FAPI-PET for GPSD Pending

2024-511977-31-01 giant cell arteritis - polymyalgia rheumatica spectrum 4
Evaluation of Glucocorticoids Plus Rituximab Compared to Glucocorticoids Plus Placebo for the Treatment of Patients With Newly-Diagnosed or … Pending

2024-516052-17-01 Patients with a diagnosis of IgAV according to Chapel H 10
The Treat-JIA trial Pending

2026-525611-13-00 Juvenil Idiopatic Arthritis 6
Tocilizumab Dose Optimization in Rheumatoid Arthritis Pending

2025-520513-30-00 Rheumatoid arthritis 6
Comparative Efficacy of Nipocalimab and Efgartigimod in Myasthenia Gravis Study ID: 80202135MYG3002 EPIC Pending

2025-521130-28-00 generalized myasthenia gravis 5
Research into the effect of Obinutuzumab on the level of PLA2R antibodies in patients with membranous nephropathy. Pending

2025-521139-35-01 Primary membranous nephropathy 4
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy… Pending

2025-521145-24-01 Active Idiopathic Inflammatory Myopathy including derma 9
Study of BMS-986353, CD19-CAR T Cells, versus SoC in Participants with Active SSc (Breakfree-SSc) Pending

2025-524337-11-00 Systemic Sclerosis 5
Randomised efficacy and safety clinical trial of PQ Birch in subjects with seasonal allergic rhinitis and/or rhinoconjunctivitis induced by … Pending

2023-507427-28-00 seasonal allergic rhinitis and/or rhinoconjunctivitis 5
Clinical Study to Evaluate the Effects of Cevostamab in Patients with Lupus with or without Active Lupus Nephritis Pending

2025-522904-26-00 Systemic Lupus Erythematosus (SLE) With or Without Acti 3
A SINGLE-ARM, OPEN-LABEL, PHASE II STUDY TO DETERMINE THE SAFETY AND EFFICACY OF OBECABTAGENE AUTOLEUCEL (OBE-CEL) IN PARTICIPANTS WITH SEVE… Pending

2024-519941-32-00 Systemic Lupus Erythematosus with Active Lupus Nephriti 4
A double-blind, randomised, placebo-controlled, first-in-human (FIH) Phase I/IIa, multi-centre trial to assess safety, tolerability, and imm… Pending

2024-515627-10-00 generalised myasthenia gravis 7
Relative bioavailability and effect of food study with GLPG3667 in healthy subjects Pending

2026-525706-35-00 inflammatory and autoimmune diseases 3
Rituximab for Treatment of Checkpoint Inhibitor Induced Immune Related Adverse Events Pending

2026-525728-18-00 All CTCAE (v. 6.0) grade 2-4 immune-related adverse eve 3
The use of [68Ga]Ga-FAPI PET/MRI in assessing disease activity in patients with Graves’ orbitopathy Pending

2025-521163-12-01 Graves' Orbitopathy 9
A PROJECT FOR TWO MULTICENTRE, PROSPECTIVE OPEN LABEL RANDOMIZED CLINICAL STUDIES TO EVALUATE THE EFFECT OF TARGETED THERAPY BASED ON KIDNEY… Pending

2024-517861-18-00 Idiopathic IgA nephropathy (IgAN) 5
Sublingual Birch Immunotherapy for Pollen-associated Food Allergy Pending

2025-523653-34-00 Pollen-associated Food Allergy 4
A study to investigate the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of a CD19/CD20 T-cell engager in participants with… Pending

2025-522932-15-00 Systemic Lupus Erythematosus 3
A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythema… Pending

2025-523670-17-00 Systemic lupus erythematosus 5
A Phase 2a Study of SUN-627 to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Impact on Measures of Neuroinflammatio… Pending

2026-525817-29-00 Multiple Sclerosis; Primary Progressive Multiple Sclero 4
Phase 1b study to assess the safety and tolerability of SR-878 in patients with rheumatoid arthritis Pending

2025-523678-17-00 rheumatoid arthritis 3
A Trial to Investigate Benralizumab in Children With Eosinophilic Diseases (CLIPS) Pending

2023-508533-14-00 Eosinophilic Disease 5