Immune System Diseases

925 trials 378 recruiting

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Phase 3 Study of Telitacicept in Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-2) Not authorised

2024-512716-21-00 Moderately to Severely Active Systemic Lupus Erythemato 5
Drug Rediscovery for rare Immune Mediated Inflammatory Diseases (DRIMID) Not authorised

2022-502968-20-01 Idiopathic Inflammatory Myopathies 4
A study to find how well budoprutug (TNT119) works and how safe it is in participants with immune thrombocytopenia Not authorised

2024-519745-30-00 Immune Thrombocytopenia (ITP) 9
PRObiotic Therapy Examining Combinatorial Therapeutics in Multiple Sclerosis - phase II, multicenter, randomised, open-label clinical trial. Not authorised

2025-520955-10-00 Multiple sclerosis 4
A PHASE III OPEN LABEL STUDY CONTROLLED BY VITAMIN D3 SUPPLEMENTATION AND THE DIFFERENCES BETWEEN YOUNG ADULTS AND SENIOR POPULATION Not authorised

2024-511889-36-01 Healthy population 5
A study to find how well budoprutug (TNT119) works and how safe it is in participants with Systemic Lupus Erythematosus Not authorised

2024-520385-57-00 Systemic Lupus Erythematosus 3
A phase 2b, single-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of oral Ladarixin in associa… Not authorised

2025-524298-18-00 new-onset autoimmune type 1 diabetes 4
A phase III, randomised, double-blind, multicentre study comparing the efficacy, safety, and immunogenicity of proposed tocilizumab biosimil… Not authorised

2022-501361-44-00 Adult patients of either gender with active moderate to 5
Phase 3 Study Assessing Rocatinlimab (AMG 451) in Adolescent Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Orbit) Not authorised

2022-501535-16-00 Atopic Dermatitis (AD) 5
Testing the safety and efficacy of combining biologic drugs in Rheumatoid and Psoriatic Arthritis Not authorised

2024-518011-19-00 Psoriatic Arthritis 4
PHASE I/IIa CLINICAL TRIAL FOR THE TREATMENT OF GRAFT VERSUS HOST DISEASE WITH A NEW GENERATION OF MESENCHYMAL STROMAL CELLS ECTOPICALLY EXP… Not authorised

2025-523139-21-00 Patients who have developed acute GVHD refractory to co 9
A Phase 3 extension study to assess the long-term safety and efficacy of remibrutinib in adult participants with moderate to severe hidraden… Pending

2025-523259-72-00 Hidradenitis Suppurativa (HS) 5
Hydroxychloroquine in progressive MS Pending

2025-522573-11-00 Multiple Sclerosis 4
A study to assess the safety and efficacy of different doses of ELV001 to treat active rheumatoid arthritis in patients with an inadequate r… Pending

2025-524005-32-00 Rheumatoid arthritis 4
Evaluation of MTX-474 in Participants with Diffuse Cutaneous Systemic Sclerosis (dcSSc) Pending

2025-523288-39-00 Diffuse Cutaneous Systemic Sclerosis (dcSSc) 4
A Long-Term Extension Study to Evaluate the Safety and Efficacy of Ritlecitinib in Participants With Severe AA Who Have Completed Studies B7… Pending

2024-515439-31-00 Alopecia areata 5
THERIPEX Pending

2025-523305-15-00 IPEX syndrome is a primary immunodeficiency caused by h 1
An autologous and antigen-specific cell-based therapy of vitamin D3-treated and myelin-derived peptide loaded tolerogenic dendritic cells in… Pending

2025-522040-40-01 Multiple Sclerosis 4
Evaluation of Allergen Specific Vaccination of Dog Allergic Patients in Swedish Practice Pending

2024-517649-15-00 Allergic rhinitis due to dog allergy 6
PREP-ANCA - Comparison of a strategy based on clinic-biological surveillance versus pre-emptive treatment with rituximab in the event of ANC… Pending

2025-522049-23-00 granulomatosis with polyangiitis and microscopic polyan 6
A study to investigate how well and safe a trial drug called AZD1163, administered as an injection, works in improving symptoms and inflamma… Pending

2025-522076-85-00 Rheumatoid arthritis 4
Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis (SMART-JIA) Pending

2025-520923-25-00 Juvenile Idiopathic Arthritis 5
An Open-Label, Phase 1b, Multiple Ascending Dose Study of OM336 in Participants with Active Sjogren’s Disease or Idiopathic Inflammatory Myo… Pending

2025-524100-29-00 Seropositive autoimmune disease: Sjogren’s disease or i 3
Phase IIb Multicenter Randomized Controlled Trial Evaluating the Efficacy of Sivelestat in Patients with Septic Coagulopathy Pending

2025-523397-16-00 Septic Coagulopathy 4