Immune System Diseases

926 trials 377 recruiting

Filter these 926 trials by phase, country and sponsor.

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Open-label, Uncontrolled Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Inebilizumab in Pediatric Par… Recruiting

2025-520988-41-00 Immunoglobulin G4 related Disease (IgG4-RD) 4 2026-05-15
A Study of KT-621 Administered Orally to Adult Participants with Moderate to Severe Eosinophilic Asthma Recruiting

2025-523180-38-00 Uncontrolled Moderate to Severe Eosinophilic Asthma 4 2026-05-12
A Phase II Open-Label Pilot Trial Assessing the Safety of Anifrolumab in Adult Patients with Primary Antiphospholipid Syndrome (APS). … Recruiting

2025-520918-64-00 Primary Antiphospholipid Syndrome (APS) 4 2026-04-24
A study to assess the effects of zigakibart on IgA nephropathy. Recruiting

2024-519699-24-00 IgA nephropathy 4 2026-04-23
Study to Evaluate the Efficacy and Safety of Deucrictibant for Prophylactic and On-demand Treatment of Angioedema Attacks in Adults with Acq… Recruiting

2025-522051-26-00 Acquired Angioedema due to C1 Inhibitor Deficiency 5 2026-04-23
A study to learn if bimekizumab given in different ways is safe and moves similarly throughout the body over time in adults Recruiting

2025-522782-30-00 CCI 3 2026-04-07
A study to investigate the efficacy and safety of frexalimab versus tacrolimus in adults undergoing kidney transplantation Recruiting

2025-521521-33-00 Kidney transplant rejection 10 2026-04-02
MP: ADAPT Forward - Master protocol of a platform study to evaluate the safety and efficacy of multiple regimens in participants with Myasth… Recruiting

2025-522492-28-00 AChR-Ab Seropositive Generalized Myasthenia Gravis, Mya 4 2026-03-13
A Long-Term Follow-up Study for Subjects Previously Treated with A Century Therapeutics Cellular Therapy Product Recruiting

2024-520222-11-00 Hematological or solid tumor malignancies or autoimmune 3 2026-03-03
A study to investigate safety, tolerability, pharmacokinetics, and pharmacodynamics of surovatamig in adult participants with rheumatoid art… Recruiting

2025-522273-10-00 Rheumatoid Arthritis 3 2026-02-24
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety … Recruiting

2024-520098-12-00 Cutaneous Lupus Erythematosus 4 2026-02-16
A Multi-Stage Study to Test a New Drug in Healthy Adult Volunteers, Then in Adults with Ulcerative Colitis Recruiting

2025-522702-21-00 Ulcerative Colitis is a type of inflammatory bowel dise 4 2026-01-26
STOP-HAE: A Phase 3 Study of ADX-324 in HAE Recruiting

2025-521352-38-00 Hereditary Angioedema 5 2026-01-16
A study of belumosudil in children with chronic graft versus host disease (schoolROCK). Recruiting

2024-511508-18-00 Chronic graft versus host disease. 9 2026-01-05
A randomized controlled phase II, double blinded trial to investigate pulmonary function after treatment with rituximab compared to placebo … Recruiting

2024-517667-23-00 Granulomatous Lymphocytic Interstitial Lung Disease (GL 4 2025-12-17
A study to test how well an oral medication called rilzabrutinib works and how safe it is for adults with immune thrombocytopenia (ITP) who … Recruiting

2025-522070-36-00 immune thrombocytopenia (ITP) 5 2025-12-15
An open label clinical study to evaluate ANX005 (also known as tanruprubart) in participants with Guillain-Barré syndrome (FORWARD Study) Recruiting

2025-522664-32-00 Guillain Barre Syndrome 5 2025-12-10
A Study to Assess the Efficacy and Safety of RO7790121 in Patients with Moderate to Severe Rheumatoid Arthritis who have not Responded to or… Recruiting

2025-521034-28-00 Moderate to Severe Rheumatoid Arthritis (RA) 4 2025-12-05
Phase 2a Study of ALXN1920 in PMN Recruiting

2025-520780-40-00 Primary Mebranous Nephropathy (PMN) 4 2025-11-26
IL-6 aGVHD Siltuximab: A phase II study to assess the efficacy and tolerability of siltuximab plus corticosteroids in first line treatment o… Recruiting

2024-510924-38-00 Grade III/IV acute graft versus host disease of the liv 4 2025-11-19
Phase III clinical trial to evaluate the efficacy and safety of specific immunotherapy with mannanconjugated allergoids for the treatment of… Recruiting

2023-508547-51-00 Aetiological treatment of moderate-to-severe allergic r 5 2025-11-18
PET-Based Imaging of Radiolabeled CIT-013 Recruiting

2025-522189-60-00 Inflammatory mediated immune diseases 4 2025-11-04
A Phase III, Open-label, Single Arm, Prospective, Multicenter Study to Assess Efficacy and Safety of Kedrion Intravenous Human Normal Immuno… Recruiting

2023-507115-35-00 Chronic Immune Thrombocytopenia (ITP) 5 2025-11-03
Study to assess the pharmacokinetics, safety, and tolerability of iptacopan in pediatric PNH patients Recruiting

2024-515926-10-00 Paroxysmal Nocturnal Hemoglobinuria (PNH) 5 2025-10-28