Immune System Diseases

926 trials 377 recruiting

Filter these 926 trials by phase, country and sponsor.

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An Open-Label, Phase 1b, Multiple Ascending Dose Study of OM336 in Participants with Active Sjogren’s Disease or Idiopathic Inflammatory Myo… Pending

2025-524100-29-00 Seropositive autoimmune disease: Sjogren’s disease or i 3
ESTIS trial: Early Stop of targeted Treatment in children with Systemic JIA. Pending

2024-518684-35-00 autoimmune disorders, joint disorders synonym: Still's 6
A clinical trial comparing how the body takes up budesonide from different forms of medicine when taken by mouth with or without food. Pending

2025-522686-29-00 Acute eosinophilic esophagitis 3
Phase IIb Multicenter Randomized Controlled Trial Evaluating the Efficacy of Sivelestat in Patients with Septic Coagulopathy Pending

2025-523397-16-00 Septic Coagulopathy 4
Prophylactic Treatment of Graves Ophthalmopathy (GO) in Newly Diagnosed Graves' Disease (GD) with Atorvastatin (ATORGO) Pending

2023-504654-35-00 Graves Ofthalmopathy 4
Efficacy of certolizumab in women with unexplained recurrent implantation failure: a double-blind randomized controlled trial (CERTIFY) Pending

2024-511869-11-00 Adult women with recurrent implantation failures (RIF) 5
A study to learn more about the amount of bimekizumab in the breast milk of women with chronic inflammatory conditions who are breastfeeding Pending

2024-518689-29-00 Hidradenitis suppurativa 3
A study to find how safe different doses of LFD-200 are and how it works in both healthy people and people with moderate to severe rheumato… Pending

2025-523409-13-00 Moderate to Severe Rheumatoid Arthritis 1
Allergen extract of Lepidoglyphus destructor. Study of the sensitivity and specificity of the diagnostic preparation in prick tests Pending

2025-523426-40-00 Allergy to Lepidoglyphus destructor 5
efficacy and safety of the use of regulatory T cells in immune hyperactivation in patients with COVID-19 and/or acute respiratory distress s… Pending

2024-519799-25-00 immune hyperactivation in COVID-19 patients and/or acut 7
Dose determination study of Phleum pratense allergenic extract for immunotherapy treatment, administered via sublingual route, standardized … Pending

2025-522730-31-00 Allergic rhinitis/rhinoconjunctivitis caused by grass p 4
Clinical trial comparing the efficacy and safety of certolizumab pegol and belimumab in patients with moderate or severe activity of systemi… Pending

2024-517753-27-01 moderate or severe activity of systemic lupus erythemat 5
Randomized Open Label Trial Evaluating Efficacy and Safety of Intravenous Immunoglobulin (IVIg, Privigen) as Add-on to SoC Versus SoC Alone … Pending

2025-522756-97-00 COVID-19 and Severely Impaired B-cell Function 4
CAALL-F01: a French protocol for the treatment of acute lymphoblastic leukemia (ALL) in children and adolescents Pending

2024-514243-29-01 This is a prospective, French, multicenter, open-label, 5
MUNC13.4 - A phase I/II Open Label non randomized study, monocentric, single arm, evaluating Safety and Efficacy of Gene Therapy of FHL 3 ca… Pending

2023-507334-24-00 Familial Hemophagocytic Lymphohistiocytosis (FHL) 1
A maintenance study to investigate the efficacy and safety of duvakitug in participants with moderately to severely active Crohn’s disease Pending

2025-521037-86-00 Immune system diseases 5
Impact of early proactive therapeutic drug monitoring on the durability and efficacy of infliximab therapy in pediatric inflammatory bowel d… Pending

2024-517759-11-00 Inflammatory Bowel Disease 6
Clinical trial to assess the efficacy and safety of a vaccine for dust mite and Lepidoglyphus destructor allergy. Pending

2025-522771-28-00 Aetiological treatment of moderate-to-severe allergic r 5
Clinical trial to assess the efficacy and safety of a vaccine for dust mite and Blomia tropicalis allergy. Pending

2025-522773-12-00 Aetiological treatment of moderate-to-severe allergic r 5
Discontinuation of disease-modifying anti-rheumatic drugs (DMARDs) in rheumatoid arthritis patients also using TNF inhibitors Pending

2026-525316-33-00 Rheumatoid arthritis 6
Anti-CD 19 CAR-T cell therapy in patients with ANCA Vasculitis - the IDEAL trial Pending

2024-517303-36-00 ANCA-IgG-positive ANCA associated vasculitis 9
An open label, balanced, randomized, single dose, two-treatment, four period, two-sequence, crossover, fully replicate, bioequivalence study… Pending

2026-525420-22-00 Seasonal allergic rhinitis 2
An open label, balanced, randomized, single dose, two-treatment, two period, two-sequence, crossover, bioequivalence study comparing Fexofen… Pending

2026-525421-20-00 Seasonal allergic rhinitis 2
Fibroblast markers to tackle fibrosis in immune-mediated inflammatory diseases Pending

2025-522834-30-01 Systemic sclerosis (SSc) 4