Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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68Ga-FAPI-46 PET-CT for molecular assessment of fibroblast activation and risk assessment in solid tumors (FAPI Basket) Recruiting

2024-511659-17-00 Solid tumors 2023-05-01
A Study of Aztreonam-Avibactam (ATM-AVI) Compared to Best Available Therapy in Pediatric Participants with Serious Gram-Negative Bacterial C… Recruiting

2022-501575-12-00 Hospital-Acquired Pneumonia 2023-04-24
Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB) Recruiting

2024-512759-19-00 first suspected infection with Mycobacterium tuberculos 2023-04-20
Master protocol of novel combinations in participants with locally advanced unresectable or metastatic gastric or gastroesophageal junction … Recruiting

2024-510977-27-00 Locally Advanced Unresectable or Metastatic Gastric or 2023-04-14
Acute Subcutaneous Semaglutide in Acute Ischemic Stroke (ASSET Trial) Recruiting

2022-501072-25-02 Ischemic Stroke 2023-04-12
A prospective program aiming at improving outcome for young adults with poor-prognosis non seminomatous germ-cell tumors (VAPOR (GETUG T06)) Recruiting

2023-505040-19-00 Non-seminomatous germ-cell tumors (including testis, re 2023-04-11
Pneumococcal vaccine response in lymph nodes Recruiting

2022-501519-15-00 Healthy volunteers 2023-04-01
INVITED trial Recruiting

2022-500906-17-01 Type 1 diabetes 2023-03-21
A Phase 2 Master Protocol to assess the efficacy and safety of FORE8394, an inhibitor of BRAF Class 1 and Class 2 alterations, in participan… Recruiting

2024-513578-23-00 Tumors harboring BRAF alterations 2023-03-21
Phase 2 trial of Translational approach to first line cHemoimmunotherapy followed by maintenance with pembrOlizumab and olaparib in Extensiv… Recruiting

2024-514666-39-00 Extensive-Stage Small-Cell Lung Cancer (ES SCLC) 2023-03-16
An open-label, dose-escalation, dose-finding, and proof-of-concept trial of SP-420 in subjects with transfusion-dependent α- or β-thalassemi… Recruiting

2023-507396-21-00 transfusion-dependent α- or β-thalassemia or low-risk m 2023-03-16
Study of the effectiveness of treatment of sarcopenia with the use of a medicinal product (nandrolone), comprehensive physiotherapy and diet… Recruiting

2024-517178-48-00 Sarcopenia is characterized by loss of the muscle mass 2023-03-15
Study of pre- and post-surgery treatment with IPH5201 and durvalumab in participants with lung cancer (MATISSE) Recruiting

2023-507778-42-00 Non-Small Cell Lung Cancer II, III 2023-03-08
Evaluation of High-Intensity Focused Ultrasound (HIFU) Hemi-ablation and short-term androgen deprivation therapy combination to enhance pros… Recruiting

2024-518680-36-00 Intermediate risk prostate cancer 2023-03-07
"APalutamide and stEReotactic body radiation therapy for low burden metastatic hormone senSItive prostate cancer, a rANdomized trial -PERSIA… Recruiting

2022-501894-37-00 prostate cancer 2023-03-02
A Phase 2B Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Namodenoson in the Treatment of Non-Alcoholic St… Recruiting

2023-510548-19-00 Non-Alcoholic Steatohepatitis (NASH) with F1-3 fibrosis 2023-03-02
Integration of the PD-L1 inhibitor atezolizumab and WT1/DC vaccination into platinum/pemetrexed-based first-line treatment for epithelioid m… Recruiting

2024-515293-27-00 Malignant pleural mesothelioma, epithelioid subtype (st 2023-02-24
AN OPEN LABEL, RANDOMISED, CONTROLLED CLINICAL TRIAL TO ASSESS THE SAFETY OF ENDOBRONCHIAL ADMINISTRATION OF ALLOGENEIC MESENCHYMAL STROMAL … Recruiting

2023-509341-12-00 Patients with lung transplant, either unilateral or bil 2023-02-22
Efficacy and safety of the combination of Cisplatin plus Nab-paclitaxel and Nivolumab with radiotherapy after maximal tumor resection in non… Recruiting

2024-518937-26-00 Patients with non-metastatic muscle invasive bladder ca 2023-02-21
Randomized prospective trial evaluating the efficacy of the antiCD38 monoclonal antibody isatuximab in the treatment of PCRA by major ABO mi… Recruiting

2024-514351-14-00 Pure cell red aplasia by major ABO mismatch after allog 2023-02-20
Evaluation of the Efficacy of an Intra-articular Injection of Autologous Microfat Combined With Autologous Platelet-enriched Plasma in the T… Recruiting

2024-516239-28-00 Radiocarpal Osteoarthritis 2023-02-17
Study of efficacy and safety of LNP023 in participants with active lupus nephritis Class III-IV, +/- V Recruiting

2023-509332-26-00 Lupus Nephritis Class III-IV, +/- V 2023-02-16
A Phase II Study to Evaluate the Imaging Potential of 68GaNOTA-Anti-MMR VHH2 for in Vivo Imaging of MMR-expressing Macrophages by Means of P… Recruiting

2024-514138-19-00 Patients with non-small cell lung cancer 2023-02-15
Prospective, open-label, non-randomized, single-arm, dose titration study to investigate the efficacy and safety of IncobotulinumtoxinA in c… Recruiting

2024-518447-38-00 multifocal spasticity of the upper and lower limb due t 2023-02-10