Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Efficacy and safety of octreotide in laparoscopic hepatectomy surgery: effect on blood loss, need for vasoactive drugs, transfusion requirem… Recruiting

2023-503613-29-00 Laparoscopic hepatectomy surgery 2023-07-18
A multicentre, randomized trial in adults with de novo Philadelphia-Chromosome positive acute lymphoblastic leukemia to assess the efficacy … Recruiting

2024-517966-40-00 Acute lymphoblastic leukemia (ALL), de novo, Ph/BCR::AB 2023-07-13
Pharmacologic treatment augmentation in chronic depression “randomized, controlled, double blinded, phase II study” Recruiting

2024-512478-86-00 Diagnosis of chronic depression 2023-07-07
AttaCH: A Phase 2, Multicenter, Long-Term, Open Label Extension Trial Evaluating Safety, Tolerability, and Efficacy of Subcutaneous Doses of… Recruiting

2022-502202-33-00 Achondroplasia in Children and Adolescents 2023-07-06
A phase II randomized trial of Lu-PSMA and Stereotactic Radiotherapy versus Radiotherapy alone for oligometastatic prostate cancer (LUST) Recruiting

2024-519347-15-00 Oligometastatic prostate carcinoma 2023-06-27
A Randomized Trial of Trastuzumab Deruxtecan and Biology-Driven Selection of Neoadjuvant Treatment for HER2-positive Breast Cancer Recruiting

2022-501504-95-00 Non-metastatic HER2-positive Breast Cancer 2023-06-23
Oxaliplatin ± nivolumab in combination with trifluridine/tipiracil or 5- fluorouracile ± nivolumab in frail patients with advanced, recurren… Recruiting

2024-512999-35-00 Patients with HER 2 negative locally advanced, recurren 2023-06-23
Genomics guided targeted post-neoadjuvant therapy in patients with early breast cancer – a multicenter, open-label, umbrella phase-II study … Recruiting

2024-514022-23-00 Early breast cancer 2023-06-23
Early detection of hepatocellular carcinoma by Hyperpolarized [1- 13C]pyruvate MRI Recruiting

2024-512490-27-00 Primary liver cancer 2023-06-19
Clinical study in adults and young patients with Primary Sclerosing Cholangitis treated with oral vancomycin or placebo Recruiting

2023-507425-42-00 Primary Sclerosing Cholangitis 2023-06-15
Randomized phase 2 study of Valproic acid combinEd with Simvastatin and gemcitabine/nab-paclitaxel-based regimens in untreated metastatic P… Recruiting

2024-518710-11-00 Metastatic pancreatic ductal adenocarcinoma (mPDAC) 2023-06-12
12-month study of probiotic effects in non-infectious uveitis treatment Recruiting

2024-517946-32-00 Non-infectious uveitis 2023-06-02
Desensitisation with imlifidase prior to kidney transplant in highly sensitised children Recruiting

2022-500230-28-00 Highly sensitised paediatric patients with a positive c 2023-06-02
Targeted therapy with anakinra for dilated cardiomyopathy: phase IIa randomized double blind monocentric clinical trial to evaluate the effi… Recruiting

2024-514861-21-00 Inflammatory dilated cardiomyopathy 2023-05-25
Window-of-opportunity umbrella platform trial of short-course pre-operative targeted treatments in patients with molecularly selected and re… Recruiting

2022-501308-90-00 Molecularly selected and resectable primary colorectal 2023-05-24
Alkaline Phosphatase as treatment of Ischemia Reperfusion Injury to prevent delayed graft function or APhIRI II Recruiting

2024-515480-66-01 End stage kidney disease - Kidney transplantation donor 2023-05-22
Study to evaluate the efficacy and safety of low-dose aspirin as an add-on to standard therapy in patients with bipolar disorder (ASPIRIN BD… Recruiting

2024-516584-86-00 Bipolar Affective Disorder 2023-05-19
Imlifidase in ANCA-associated Vasculitis Recruiting

2024-516727-13-00 Anti-neutrophil cytoplasmic antibody (ANCA) associated 2023-05-17
Venetoclax in combination with Ibrutinib and Rituximab or conventional chemotherapy (Bendamustine) and Ibrutinib and Rituximab in patients w… Recruiting

2022-501808-96-00 Mantle Cell Lymphoma 2023-05-15
An adaptive, Phase 2, double-blind, randomized, placebo-controlled, multicenter study to evaluate the safety, tolerability, immunogenicity, … Recruiting

2022-500292-31-00 Early stages of idiopathic Parkinson's Disease 2023-05-12
Migraine and High Flow Oxygenotherapy at the Emergency Department (MiOx) Recruiting

2022-501133-23-00 MIGRAINE 2023-05-11
Sotatercept in Children with Pulmonary Artery Hypertension on Standard of Care Recruiting

2023-504861-22-00 Pulmonary arterial hypertension 2023-05-05
Immune-Related Rheumatological and neurological Adverse Events study. Recruiting

2024-516631-27-00 Cancer (all types) 2023-05-05
EDEN : Etude de désescalade thérapeutique et d'évaluation du marqueur miRNA M371 pour les séminomes de stade IIa/IIb < 3 cm Recruiting

2024-514636-25-00 Stage IIa/IIb < 3 cm seminoma 2023-05-04