Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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NeoAdjuvant PErsonalized therapy in Estrogen Receptor positive breast cancer (NAPEER) - An open label phase II trial of endocrine treatment… Recruiting

2023-510093-13-00 Patients with hormone receptor positive HER2 negative b 2022-05-11
Window-of-opportunity proof-of-concept, non-randomized, open-label phase II trial of Olaparib given alone (cohort A) or in combination with … Recruiting

2024-511780-28-00 Patients with presumed and previously untreated advance 2022-05-05
A non blinded phase-II study with 3 randomized patient groups of individualized suppression of the patient's immune system with donor modifi… Recruiting

2024-513446-12-00 Living donor kidney transplantation 2022-05-03
Fecal Microbiota Transplantation in the prevention of complications after allogeneic hematopoietic stem cell transplantation for hematologic… Recruiting

2024-512969-14-01 Patient who underwent Allogeneic hematopoietic stem cel 2022-05-02
Temozolomide and irinotecan consolidation in patients with MGMT silenced, microsatellite stable colorectal cancer with persistence of minima… Recruiting

2024-515681-14-00 Stage II (pT4)/III colorectal cancer with positive circ 2022-05-02
A study of MK-7240/PRA023 in patients with Systemic Sclerosis Associated with Interstitial Lung Disease Recruiting

2023-509743-27-00 Systemic sclerosis associated with interstitial lung di 2022-04-29
The Effect of tinzaparin on Biomarkers in FIGO Stage III-IV Ovarian Cancer Patients Undergoing Neoadjuvant Chemotherapy – A randomized pilot… Recruiting

2024-515450-24-00 Epithelial ovarian cancer 2022-04-22
PEMBROCABOSARC : Combination of pembrolizumab and cabozantinib in patients with advanced sarcomas Recruiting

2023-509496-16-00 Advanced /metastatic sarcomas: undifferentiated pleomor 2022-04-21
Nivolumab and ipilimumab in patients with dMMR and/or MSI metastatic colorectal cancer resistant to anti-PD1 monotherapy: An open-label phas… Recruiting

2024-516313-20-00 Metastatic colorectal cancer 2022-04-19
Phase IIa Clinical Trial: Feasibility Study on Non-Invasive Simultaneous Hyperpolarized [1-13C]Pyruvate Magnetic Resonance Spectroscopy and … Recruiting

2024-516131-28-00 Breast cancer, neuroendocrine neoplasms, lymphomas, sar 2022-04-18
Phase I/II trial of meclofenamate in progressive MGMT-methylated glioblastoma under temozolomide second-line therapy (MecMeth/ NOA-24) Recruiting

2024-511264-89-00 Glioblastoma 2022-04-11
A prospective, randomized, multicenter, comparative study of the efficacy of imatinib resumption combined with atezolizumab versus imatinib … Recruiting

2022-503068-34-00 Metastatic Gastrointestinal Stromal Tumor 2022-04-06
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of INCB000928 in Participan… Recruiting

2023-504129-38-00 Fibrodysplasia Ossificans Progressiva 2022-03-31
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants Wi… Recruiting

2023-504599-10-00 Chronic lymphocytic leukemia recurrent 2022-03-29
Antibiotic Impregnated Bone Graft to reduce infection in hip replacement - the ABOGRAFT trial Recruiting

2024-510921-25-00 Prosthetic Joint Infection 2022-03-18
Combined Nabpaclitaxel Pressurized IntraPeritoneal Aerosol Chemotherapy with systemic Nabpaclitaxel-Gemcitabine chemotherapy for pancreatic … Recruiting

2024-518938-81-00 Pancreatic cancer with peritoneal metastases 2022-03-09
Exploration of the pathophysiology of cluster headache (AVF) in PET-MRI using [18F]F13640 Recruiting

2024-513873-36-00 Nervous System Diseases 2022-02-28
EORTC 1820-CLTF: Open-Label, phase II, Multi-Center, study of Anti-CCR4 Monoclonal Antibody (mogamulizumab) Plus Total Skin Electron Beam th… Recruiting

2022-502434-10-00 Cutaneous T-cell lymphoma, a category of cancers of lym 2022-02-22
HERES trial: Trastuzumab and standard treatment with chemo- and immunotherapy as first line treatment for HER2 positive esophageal squamous … Recruiting

2024-516318-40-02 Esophageal Cancer 2022-02-21
“NALPAC” A NON-COMPARATIVE RANDOMIZED PHASE 2 STUDY, EVALUATING THE EFFICACY OF 5-FU + NALIRI AND 5-FU + NALIRINOX FOR METASTATIC PANCREATIC… Recruiting

2024-516336-97-00 METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA 2022-02-21
Induction treatment of patients with head and neck squamous cell carcinoma using simultaneous chemotherapy and low-dose radiotherapy (iCHRTL… Recruiting

2024-517480-23-00 Head and neck squamous cell carcinoma 2022-02-17
A study to evaluate long-term Infigratinib in children with Achondroplasia Recruiting

2024-513857-55-00 Achondroplasia 2022-02-08
API-AHAI - Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a P… Recruiting

2024-513191-17-00 autoimmune hemolytic anemia 2022-02-03
Benefit of positons emission tomography / 68Gallium citrate tomodensitometry for artificial hip and knee chronic infection diagnosis Recruiting

2024-515781-13-00 Prosthetic joint infection 2022-02-02