Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Tucatinib in combination with Oral Etoposide (VP16) and Trastuzumab in Patients with metastatic HER2+ Breast cancer (TUC-TOC) Recruiting

2022-500743-20-00 Metastatic HER2+ Breast cancer 2023-12-19
Watch-and-wait strategy to initiate Dostarlimab-based Immunotherapy in localized deficient mismatch repair (dMMR) and/or microsatellite inst… Recruiting

2023-506102-39-00 metastatic gastric cancer 2023-12-18
Neo-adjuvant pembroliuzmab as an alternative treatment for MMRd uterine cancer Recruiting

2024-516736-10-00 Mismatch repair deficient endometrial cancer / uterine 2023-12-18
Phase II, open label, single arm study of PembrolizumAb combiNeD with cisplatin or carbOplatin and etoposide in treatment naïve advanced meR… Recruiting

2022-500988-12-00 Advanced, naïve, Merkel cell carcinomas 2023-12-18
LSTA1 for subjects with newly diagnosed Glioblastoma Multiforme when added to standard of care (temozolomide) versus temozolomide Recruiting

2023-506813-23-00 Glioblastoma Multiforme 2023-12-18
Mifepristone and Letrozole in Ectopic Pregnancy (MILE) Recruiting

2023-503935-16-00 Ectopic pregnancy 2023-12-15
Fremanezumab for pain in Complex Regional Pain Syndrome Recruiting

2022-503167-15-00 Complex Regional Pain Syndrome 2023-12-11
SGM-T1: SGM-101 tumor targeted fluorescence endoscopy in rectal polyps with suspected T1 adenocarcinoma or high grade dysplasia Recruiting

2024-510769-41-00 Early rectal cancer 2023-12-07
A feasibility study of SGM-101, a fluorochrome-labeled anti-carcinoembryonic antigen monoclonal antibody for the intraoperative detection of… Recruiting

2024-510767-30-00 Brain metastases 2023-12-04
Fully hybrid 18F-PSMA PET/MRI as one-stop approach for the diagnosis of clinically significant prostate cancer Recruiting

2024-512859-21-00 Patients with clinical suspicion of clinically relevant 2023-12-04
Cerebrolysin in CADASIL Recruiting

2024-513828-42-00 Cerebral Autosomal Dominant Arteriopathy with subcortic 2023-11-29
Study aiming to assess the clinical impact of dostarlimab on occurrence of second primary cancer in patients with cured primary cancer Recruiting

2022-501316-34-00 Patient cured from a primary cancer and at risk of 2nd 2023-11-27
Efficacy and tolerability of the combination of anifrolumab (300 mg IV) and phototherapy versus phototherapy in adults with progressive viti… Recruiting

2024-512041-17-00 Patient with non-segmental (symmetrical) vitiligo with 2023-11-27
Evaluaton of ibrutinib therapy for the treatment of autoimmune Hemolytic Anemia in Patients with Chronic Lymphocytic Leukemia/Small Lymphocy… Recruiting

2023-509793-38-00 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma 2023-11-24
ALEPRO: abemaciclib and letrozole in estrogen receptor positive rare ovarian cancer Recruiting

2023-503533-21-00 Low-grade serous ovarian cancer 2023-11-21
Effect of dapagliflozin on the quality of life and exercise capacity of patients with amyloid transthyretin cardiac amyloidosis: a pilot, ph… Recruiting

2023-504041-31-00 ATTR Cardiac Amyloidosis 2023-11-17
Long-term neuropsychologic outcome of pre-emptive mTOR inhibitor treatment in children with tuberous sclerosis complex (TSC) under 4 months … Recruiting

2022-502332-39-00 Tuberous sclerosis complex (TSC) 2023-11-15
Intravenous Fish Oil based Lipid Emulsion to enhance recovery in High-Risk Cardiac Surgery Patients: a phase II multicenter trial Recruiting

2023-503490-38-00 critical illness, intensive care unit (ICU), surgery 2023-11-15
Validation of ICG-99mTc-nanoscan as hybrid tracer for sentinel node biopsy Recruiting

2024-519351-28-00 Patients with melanoma of the head/neck or the upper pa 2023-11-15
FOENIX-CCA4 Recruiting

2023-503665-39-00 Advanced cholangiocarcinoma 2023-11-14
Indocyanine green to assess vascularity of ileal conduit anastomosis and regulate ureteral resection margins during pelvic exenteration for … Recruiting

2024-518783-13-00 Patients with gynecological cancers undergoing pelvic e 2023-11-09
LiBRA – Lithium treatment to prevent cognitive impairment after brain radiotherapy. Recruiting

2023-504071-24-00 Brain tumor 2023-11-07
Intratumoral Flu Vaccine and Pembrolizumab in Colorectal Cancer Recruiting

2023-503228-17-00 Colorectal Cancer 2023-11-06
Expression-linked and R-ISS-adapted stratification for first line therapy in multiple myeloma patients (ELIAS) Recruiting

2022-500453-16-00 Multiple Myeloma 2023-10-30