Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Exploratory evaluation of the effect of cholestyramine on serum levels of persistent organic pollutants in obese patients Recruiting

2023-505116-37-00 Obesity 2024-02-08
Efficacy of the Doravirine/Tenofovir Disoproxil Fumarate/Lamivudine combination in people living with HIV with a history of M184V/I mutation… Recruiting

2023-505845-17-00 Patients living with HIV-1 who are virologically contro 2024-02-08
Frexalimab in preservation of endogenous insulin secretion compared to placebo in adults, adolescents and children on top of Insulin therapy… Recruiting

2022-500531-36-00 Type 1 diabetes mellitus 2024-02-02
Trial evaluating the efficacy and the safety of FOLFIRINOX3 treatment in patients with unresectable locally advanced or metastatic pancreati… Recruiting

2023-505889-29-01 Patients with unresectable locally advanced or metastat 2024-02-01
[18F]AlF-PSMA-11 PET in advanced thyroid and head and neck carcinoma Recruiting

2022-503036-13-00 Head and neck squamous cell carcinoma, thyroid carcinom 2024-02-01
GENEPID: A 44-weeks monocentric open study assessing the efficacy and safety of Deucravacitinib in adults with Inflammatory EPidermal GENode… Recruiting

2022-502879-32-00 Inflammatory EPidermal GENodermatoses 2024-01-30
Clinical and translational controlled study of Perampanel treatment around Surgery in patients with progressive glioblastoma (PerSurge) Recruiting

2023-503938-52-00 Progressive Glioblastoma 2024-01-26
Pan-tumor neoadjuvant basket study of immune check-point inhibition and novel IO combinations (NEOASIS) Recruiting

2023-505756-21-00 dMMR tumors consisting of but not limited to; Colorecta 2024-01-26
Neural Stem Cell Treatment for Amyotrophic Lateral Sclerosis: A multicenter, randomized placebo controlled and biological endpoints clinical… Recruiting

2024-518888-35-00 amyotrophic lateral sclerosis patients 2024-01-24
Multicenter Phase 2 study to evaluate the efficacy and safety of Cetuximab in combination with Encorafenib plus Binimetinib as induction tre… Recruiting

2022-502413-29-00 BRAF V600E mutated and microsatellite stable (MSS) adva 2024-01-22
Phase 2a non-commercial and non-randomized intervention study evaluating the efficacy of crizotinib in the treatment of children with severe… Recruiting

2024-516607-16-00 Neurofibromatosis type 2 is a genetically determined pr 2024-01-17
Discontinuation of CDK4/6 inhibitors in patients with metastatic HR positive, HER2 negative breast cancer with durable disease control: A ra… Recruiting

2023-504141-31-00 Metastatic HR positive, HER2 negative breast cancer 2024-01-17
A study to investigate the effect of adding cobicistat to venetoclax and azacitidine in patients with acute myeloid leukemia (AML) who are i… Recruiting

2023-505379-61-00 Acute Myeloid Leukaemia 2024-01-17
AGNOSTIC THERAPY IN A PHASE II, MULTICENTER, SINGLE-ARM STUDY IN FIRST-LINE TREATMENT OF DURVALUMAB (MEDI 4736) IN ASSOCIATION WITH CARBOPLA… Recruiting

2023-505078-13-00 EXTENSIVE STAGE ‐ EXTRAPULMONARY SMALL CELL CARCINOMA 2024-01-16
PHASE II CLINICAL TRIAL TO ESTABLISH THE SAFETY OF THE USE OF EXPANDED ALLOGENEIC FETAL UMBILICAL CORD STEM MESENCHYMAL CELLS IN PRETERM PAT… Recruiting

2024-516677-79-00 Premature patients with bronchopulmonary dysplasia 2024-01-11
A Multicenter, Open-Label, Dose-Finding Clinical Trial to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy of RV… Recruiting

2023-505911-19-00 Acute Myeloid Leukemia 2024-01-05
Clinical trial of the efficacy and safety of nicotinamide in patients with diabetes mellitus type 2 and liver fibrosis Recruiting

2023-504100-28-00 Hepatic fibrosis 2024-01-02
Dose-Ranging Efficacy Study of rapamycin cream applied topically in subjects diagnosed with port wine stains Recruiting

2025-520821-19-00 Subjects diagnosed with port wine stains 2024-01-02
Mitapivat in Membranopathies Recruiting

2023-503271-24-01 erythrocyte membranopathies 2023-12-29
An Extension Study to Monitor Long-Term Safety of LUM-201 Treatment in Children with Idiopathic Growth Hormone Deficiency Recruiting

2023-504020-25-00 Idiopathic Growth Hormone Deficiency 2023-12-28
COBRA - Chemoablation for Low Grade Bladder Cancer: A single arm, prospective, open-label, investigator-initiated Phase 2 study Recruiting

2024-517106-28-00 Bladder cancer 2023-12-27
Efficacy of early intravenous high-dose vitamin C in post-cardiac arrest shock: a multicenter, randomized controled to standard treatment, o… Recruiting

2022-500717-64-00 cardiac arrest 2023-12-27
Study on the effect of 2 immunotherapy drugs in combination with radioactive glass spheres on the survival in liver cancer Recruiting

2024-515127-11-00 hepatocellular carcinoma 2023-12-21
A Phase 2 Study of Teclistamab in Combination with Daratumumab or Lenalidomide in Elderly Patients with Newly Diagnosed Multiple Myeloma - I… Recruiting

2024-514101-65-00 Multiple Myeloma 2023-12-21