Phase I – Other

1,082 trials 243 recruiting

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A Study Evaluating the Safety and Pharmacokinetics of Escalating Doses of Forimtamig in Participants With Relapsed or Refractory Multiple My… Ended

2023-504571-25-00 Relapsed or Refractory Multiple Myeloma 2020-10-20
A Study of Oral Tazemetostat in Subjects With Moderate and Severe Liver Impairment With Advanced solid tumors or hematological malignancies Ended

2024-517141-13-00 Advanced solid tumors, or hematological malignancies an 2020-10-07
A study to assess how radium-223 moves through the patients with prostate cancer receiving radium-223 dichloride treatment. Ended

2023-506435-15-00 Prostate cancer 2020-08-25
Investigation the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7248824 in Participants with Angelman Syndrome Ended

2024-514797-45-00 Angelman Syndrome (AS) 2020-08-25
A study of safety and efficacy of novel targeted therapy combinations in adult patients with advanced or metastatic colorectal cancer. Ended

2023-510379-77-00 Advanced or metastatic BRAF V600 colorectal cancer. 2020-08-05
Study to evaluate the addition of an experimental drug, CC-90010, to the usual treatment of brain cancer after surgery Ended

2024-511171-15-00 Subjects with newly diagnosed WHO Grade IV glioblastoma 2020-07-06
Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001) Ended

2023-509542-35-00 Advanced Pancreatic cancer, Unresectable Glioblastoma a 2020-03-02
Safety and pharmacokinetics of ceftolozane/tazobactam in pediatric participants with nosocomial pneumonia Ended

2022-501110-56-00 Nosocomial infection, Pneumonia 2020-02-26
Trastuzumab Deruxtecan, and pembrolizumab in participants with Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer Ended

2023-509866-39-00 Locally advanced/metastatic breast or non-small cell lu 2020-02-14
Inhibition of AKT in combination with antibodies targeting the protein HER2 in patients with advanced or metastatic breast cancer and with a… Ended

2023-508826-92-00 Patients with PIK3CA-mutant, HER2-positive locally adva 2020-02-14
A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents Ended

2023-507904-30-00 solid tumors 2020-01-27
Gene Therapy for Pyruvate Kinase Deficiency (PKD): A Phase I Clinical Trial to Evaluate the Safety of the Infusion of Autologous CD34+ Cells… Ended

2024-511520-13-00 Inherited metabolic disorder of the enzyme pyruvate kin 2019-11-04
Pembrolizumab plus autologous dendritic cell vaccine in patients with advanced mesothelioma who have failed prior therapies Ended

2023-508756-19-00 Mesothelioma 2019-10-29
Combining drug-eluting bead chemoembolization and radioembolization for treatment of colorectal liver metastases: DEBIR90Y study Ended

2024-514767-26-00 colorectal liver metastases 2019-10-11
A Phase I, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Patients with Re… Ended

2024-515123-11-00 Lymphoma 2019-09-05
A Phase 1b, Multicenter Study to Determine the Dose, Safety, Efficacy and Pharmacokinetics of TRK-950 when Used in Combinations with Selecte… Ended

2024-513915-28-00 Bladder cancer, Cholangiocarcinoma, Colorectal Cancer, 2019-06-14
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients with Urothelial Carcinoma… Ended

2024-511316-25-00 Urothelial carcinoma (UC) 2019-06-04
A Phase IB Study to determine efficacy and safety of Durvalumab and/or novel anti-cancer agents, with or without chemotherapy, in patients w… Ended

2024-511956-42-00 Metastatic Non-Small Cell Lung Cancer (NSCLC) 2019-05-14
A clinical study to test the safety (any good or bad effects) of CC-90011 in combination with standard of care (cisplatin and etoposide), on… Ended

2023-509800-14-00 extensive stage small cell lung cancer 2019-02-25
Combination of Talimogene Laherparepvec (modified Herpes Virus) with atezolizumab (monoclonal antibody) in patients with residual breast can… Ended

2023-508550-25-00 Pre and post-menopausal women with resectable primary b 2018-12-10
A Study Evaluating the Safety and Efficacy of KTE-X19 in pediatric and adolescent Subjects with Relapsed/Refractory B-precursor Acute Lympho… Ended

2023-509440-97-00 Relapsed/Refractory B-precursor Acute Lymphoblastic Leu 2018-09-25
Pharmacokinetics of antibiotics in cerebrospinal fluid of children with external ventricular drain Ended

2024-515791-12-00 patients with external ventricular drain 2018-08-30
Intermittent ibrutinib in chronic lymphocytic leukemia Ended

2023-508638-32-00 Chronic lymphocytic leukemia 2018-04-06
A study to evaluate the effect of multiple doses of carbamazepine and itraconazole on how long JNJ-55308942 stays in the body (pharmacokinet… Ended

2023-504055-27-00 Bipolar depression