Phase I – Other

1,082 trials 243 recruiting

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Study of Avelumab in combination with Lenvatinib for children with primary CNS tumors Ended

2024-512940-51-00 Central Nervous System Tumors 2021-11-24
Phase IB Study to Assess the Safety, Tolerability and Efficacy of PM14 in combination with Atezolizumab in Pretreated Patients with Selected… Ended

2023-509688-25-00 Advanced solid tumors 2021-11-23
A Randomized, Open-Label, Phase 1-2 Study of ASTX727 Low Dose (ASTX727 LD) Extended Schedule in Subjects with Lower Risk (IPSS Low or Interm… Ended

2024-516296-32-00 Myelodysplastic Syndromes (MDS) 2021-11-11
Phase 1b Study of Dato-DXd in Combination with Pembrolizumab with or without Platinum Chemotherapy in Advanced or Metastatic Non-Small Cell … Ended

2023-508003-20-00 Non-small cell lung cancer 2021-09-27
A Drug Absorption Study of MK-3475A in Participants with Solid Tumors Ended

2023-505340-19-00 Advanced or Metastatic Solid Tumors 2021-09-20
Single Dose Pharmacokinetics and Relative Bioavailability of Sayana Press via Upper Arm Injection Relative to Anterior Thigh and Abdomen Ended

2024-513561-39-00 long-term female contraception 2021-09-08
Study to Evaluate the Safety and Efficacy of Treatment with NLM-001 before Standard Chemotherapy plus Zalifrelimab in Patients with Advanced… Ended

2024-518852-22-00 Advanced Pancreatic Cancer 2021-09-03
A study of enfortumab vedotin given in the bladder for treatment of patients with non-muscle invasive bladder cancer (NMIBC). Ended

2023-503388-40-00 Non-muscle invasive bladder cancer 2021-08-24
This study aims to find the best dose of BI 907828 (brigimadlin) in patients with different types of advanced cancer (solid tumors) Ended

2024-511503-41-00 Advanced or metastatic solid tumors 2021-08-13
A study to test different doses of BI 1823911 alone and combined with other medicines in people with different types of advanced cancer with… Ended

2024-512805-18-00 solid tumour harbouring G12C mutation 2021-08-03
A Phase I Study of Belantamab Mafodotin in Multiple Myeloma Participants with Normal and Impaired Hepatic Function Ended

2023-509915-10-00 Relapsed or Refractory Multiple Myeloma 2021-07-27
Clinical study to compare two cutaneous ointments with the active substance methylprednisolone aceponate 0.1% and one cutaneous ointment wit… Ended

2024-514548-10-01 Mild to moderate atopic dermatitis 2021-07-26
A Phase 1b Study of the MALT1 Inhibitor JNJ-67856633 and Ibrutinib in Combination in Relapsed or Refractory B cell Non-Hodgkin Lymphoma and … Ended

2024-512689-32-00 Non-Hodgkin lymphoma and chronic lymphocytic leukemia 2021-07-15
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Tumor Activity of Inavolisib in Combination with Paclit… Ended

2023-506745-33-00 Locally Advanced or Metastatic Solid Tumors 2021-07-12
Clinical trial to assess the safety and efficacy of AloCELYVIR in children, adolescent and young adults with diffuse intrinsic pointine glio… Ended

2022-502516-37-00 Newly diagnosed Diffuse Intrinsic Pointine Glioma (DIPG 2021-07-12
Phase I Clinical Study to Assess Safety and Efficacy of Repotrectinib Combined with Osimertinib in Patients with Advanced, Metastatic EGFR M… Ended

2023-509776-41-00 Non-small cell lung cancer (NSCLC) 2021-06-30
A Phase 1b, Open-Label Study of Eftozanermin Alfa (ABBV-621) in Combination with Bortezomib and Dexamethasone in Subjects with Relapsed or R… Ended

2024-512640-36-00 Multiple Myeloma 2021-05-26
An open-label, long-term, safety and tolerability study of SAR445088 in participants with cold agglutinin disease previously treated with SA… Ended

2023-510210-68-00 Autoimmune haemolytic anaemia 2021-05-26
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Belvarafenib as a Single Agent and in Combination with Either Cobimetinib … Ended

2022-503107-21-00 NRAS-mutant advanced cutaneous melanoma 2021-05-14
A Phase 1b Study of AMG 757 in Subjects with Neuroendocrine Prostate Cancer Ended

2024-513316-10-00 Adult subjects with de novo or treatment-emergent neuro 2021-04-20
A Phase 1b, Open-Label Study of the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-64264681 in Combination with JNJ-67856633 in Parti… Ended

2024-512687-66-00 non-Hodgkin lymphoma and chronic lymphocytic leukemia 2021-02-16
A Phase 1 Study of HMPL-306 in Advanced Hematological Malignancies with Isocitrate Dehydrogenase (IDH) Mutations Ended

2024-516369-36-00 - Acute myeloid leukemia - Myelodysplastic syndrome/ My 2021-02-09
A Phase 1 Study of HMPL-306 in Locally Advanced Solid Tumors with IDH mutations Ended

2024-516370-30-00 - Locally advanced or metastatic solid tumors - Cholang 2021-02-09
A Phase 1, Open-Label Study of the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-64264681 in Participants with Non-Hodgkin Lymphoma … Ended

2024-512686-13-00 non-Hodgkin lymphoma and chronic lymphocytic leukemia 2021-01-28