Phase I – Other

1,082 trials 243 recruiting

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A study to compare how different substances (caffeine, warfarin, omeprazole, metoprolol, and midazolam) are handled by the body of healthy p… Ended

2024-514622-22-00 1. Patients with compensated liver cirrhosis due to any 2023-04-25
A Phase I Clinical Study Evaluating the Safety of Peptide Receptor Radionuclide Therapy (PRRT) with 177Lu-DOTA0-Tyr3-Octreotate in Children … Ended

2024-515552-21-00 Recurrent or refractory neuroblastoma. 2023-04-17
Effects of NT-0796 in Healthy Volunteers and Patients with Parkinson’s Disease Ended

2023-503203-29-00 Parkinson's Disease 2023-04-12
Albendazole pharmacokinetics in plasma, intra-cystic fluid and cystic tissue of human cystic and alveolar echinococcosis Ended

2024-518548-19-00 Human echinococcosis 2023-03-27
Phase 1b study investigating the association of NP137 with mFOLFIRINOX in locally advanced pancreatic ductal adenocarcinoma LAP NET 1 Ended

2022-500905-42-00 pancreatic ductal adenocarcinoma 2023-03-24
A Phase 1b Trial of ARV-471 in Combination with Everolimus in Patients with ER+, HER2– Advanced or Metastatic Breast Cancer Ended

2024-513284-30-00 ER+, HER2– Advanced or Metastatic Breast Cancer 2023-03-22
Evaluation of the value of 18F-Fluoromisonidazole (18F-FMISO) positron emission tomography hypoxia imaging in idiopathic pulmonary fibrosis … Ended

2024-515303-19-00 idiopathic pulmonary fibrosis 2023-03-20
A Phase 1 Study of the SHP2 Inhibitor BBP-398 (formerly known as IACS-15509) in combination with the KRAS-G12C Inhibitor Sotorasib in Patien… Ended

2022-501363-40-00 Advanced or metastatic solid tumors with a KRAS-G12C mu 2023-03-17
Debio 0123 in combination with carboplatin and etoposide in adult participants with small cell lung cancer that recurred or progressed after… Ended

2024-510980-40-00 Small cell lung cancer 2023-03-09
Safety, tolerability, pharmacokinetics, and pharmacodynamics of intravenous and subcutaneous multiple rising doses of BI 765250 versus place… Ended

2024-512420-10-00 Plaque psoriasis 2023-03-09
Study of exposure to substances prohibited by the World Anti-Doping Agency in healthy volunteers. Proof of concept. Ended

2022-502216-36-00 Healthy volunteers 2023-02-27
A Randomized, Double-Blind (Sponsor-Unblinded), Placebo-Controlled, Single And Multiple Ascending Dose Study To Evaluate Safety, Tolerabilit… Ended

2024-512987-74-00 Disorders characterized by a deficit in GABAergic signa 2023-02-27
A study investigating the safety, tolerability, absorption, excretion and effects of a new drug for the treatment of epilepsy. Ended

2022-502638-17-00 Epilepsy 2023-02-03
A Phase 1b, Open-Label, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activ… Ended

2022-500116-18-00 Advanced Solid Tumors 2023-01-09
An Open-label, Randomized, Three-period, Crossover Study to compare the Pharmacokinetics of GB1211 upon dosing a capsule under fasting condi… Ended

2022-502200-67-00 Non-small Cell Lung Cancer 2022-12-27
Cardiac safety of treosulfan chemotherapy prior to stem cell transplantation in patients with leukemia. Ended

2024-517377-24-00 Subjects with AML ( Acute myeloid leukaemia) or MDS (My 2022-12-20
A Phase I, Open-Label Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytis… Ended

2022-500921-34-00 Nicotine addiction 2022-12-13
A study in healthy women to test whether BI 425809 influences the amount of a contraceptive in the blood Ended

2022-500050-42-00 Healthy 2022-11-24
A study investigating the pain-relieving effects of a new drug in healthy adults Ended

2022-501804-80-00 Acute and chronic neuropathic pain secondary to diabeti 2022-11-17
DMT in healthy subjects Ended

2024-518020-68-00 Stroke 2022-11-15
A study to investigate pharmacokinetics and safety of rupatadine (10 mg) and its active metabolites in participants with hepatic impairment … Ended

2022-500774-34-00 Urticaria 2022-11-08
A study to investigate pharmacokinetics and safety of rupatadine (10 mg) and its active metabolites in participants with renal impairment co… Ended

2022-500775-31-00 Allergic rhinitis 2022-11-08
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneously Administered Mosunetuzumab to Partici… Ended

2023-509188-26-00 Systemic Lupus Erythematosus (SLE) 2022-10-27
A Phase 1 Dose-escalation Study of UGN-301 in Patients With Recurrent Non-muscle Invasive Bladder Cancer (NMIBC) Ended

2023-508404-37-00 Non-muscle Invasive Bladder Cancer 2022-10-26