Phase I – Other

1,081 trials 241 recruiting

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Phase 1 study assessing the pharmacokinetics of NEX-22A in subjects with T2D Not authorised

2023-508054-25-00 Type 2 diabetes
ExplOratory, Phase 0 Study to assess biodisTribution and PosItron EMission Tomography (PET) Imaging kinetics of [64Cu]Cu-PSMA-R2 in metaStat… Not authorised

2023-508473-86-00 metastatic prostate cancer
Psilocybin's effects on anhedonia Not authorised

2023-509009-59-00 Major Depressive Disorder
An open-label, prospective, randomised, cross-over trial to assess the pharmacokinetics of an amorphous formulation of sorafenib in mesoporo… Not authorised

2024-514496-18-00 Hepatocellular carcinoma, renal cell carcinoma and diff
A trial to learn how ceralasertib affects the way certain medications move throughout the body over time and how safe it is to use ceralaser… Not authorised

2024-516611-24-00 Advanced solid tumour
Phase I-Ib clinical trial of safety and immunobiology of prophylactic infusion of lymphocytes and NK cells after Allo-HCT. Not authorised

2024-517002-28-00 graft-versus-host disease
A study to find how well budoprutug (TNT119) works and how safe it is in participants with Systemic Lupus Erythematosus Not authorised

2024-520385-57-00 Systemic Lupus Erythematosus
IMPD-Q-only application Not authorised

2025-524730-26-00 prick test-induced itch
A Study to Learn About the Safety, Tolerability and Blood Levels of a Study Medicine (called sisunatovir) in Infants and Children with RSV L… Not authorised

2023-504425-39-00 Respiratory Syncytial Virus (RSV) Infection
A Phase I Clinical Trial of CART cell therapy for refractory/ relapsed acute lymphoblastic leukemia with unmet needs in children, adolescent… Not authorised

2023-509723-41-00 Refractory/ relapsed acute lymphoblastic leukemia in ch
Intraperitoneal treatment with fosfomycin, metronidazole and recombinant human granulocyte-macrophage colony-stimulating factor in patients … Not authorised

2024-520317-49-00 peritonitis
An open label safety and efficacy study of allogenic adipose tissue-derived mesenchymal stromal cells on autism and gastrointestinal symptom… Not authorised

2025-523699-21-00 Gastrointestinal symptoms
Safety of stem cells in treatmemt of retinal diseases. Pending

2023-503573-38-00 Retinal degenerative diseases
A Phase 1, Double-blind, Randomized, Placebo-controlled, First-in-Human Study of Orally Administered DF-006 to Evaluate the Safety, Tolerabi… Pending

2023-504288-18-00 Chronic Hepatitis B
Oxytocine and migraine Pending

2023-504690-21-00 This is a study in healthy volunteers. We will study t
A study to learn about how different drugs interact with each drug in a new 7-drug mixture as they move into, through, and out of the body i… Pending

2023-504870-39-00 drug-drug interactions (DDI)
SEDICAN: Sex differences in the acute effects of cannabis Pending

2023-505159-35-00 N/A - healthy volunteers
A monocentric Phase I pivotal pharmacology study for the determination of the local and systemic exposure of locally applied Minocycline in … Pending

2023-506126-36-00 Periodontitis
In situ injection of anti-angiogenics in patients with brain arteriovenous malformations not eligible for exclusion treatment: phase I trial… Pending

2023-506991-28-00 Cardiology and vascular disease
A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of… Pending

2023-507521-41-01 rheumatoid arthritis
A study to compare the relative potency of salbutamol administered via metered dose inhalers containing propellants HFA-152a to HFA-134a in … Pending

2024-511220-14-00 Mild Asthma
Phase I clinical trial of TG4050 combined with nivolumab in patients with Non-Small Cell Lung Cancer. Pending

2024-514001-65-00 Non-Small Cell Lung Cancer
Prospective feasibility pilot study evaluating the value of [68Ga]Ga-PENTIXAFOR PET-CT in patients with locally advanced or metastatic Small… Pending

2024-514057-30-00 cell lung carcinoma
Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable high grade gliomas patients Pending

2024-514144-85-02 Glioblastoma