Phase I/II – Other

643 trials 280 recruiting

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A Single Arm, Open Label, Phase 1/2 Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients with Sickle Cell D… Pending

2024-519881-32-00 Sickle Cell Disease
FIDES: Focused Ultrasound-mediated Blood-Brain Barrier Opening In Pontine Diffuse Midline Glioma (DMG) to Enhance Systemic Therapy with Temo… Pending

2025-520814-78-00 Diffuse Midline Glioma, H3K27-altered
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy… Pending

2025-521145-24-01 Active Idiopathic Inflammatory Myopathy including derma
Study of the safety and efficacy of asciminib in pediatric and young adult participants with r/r Ph+ or ABL-class Ph-like ALL Pending

2025-522019-40-00 relapsed or refractory BCR::ABL1-positive (Philadelphia
TGD001 Treatment in Thrombotic Microangiopathies Pending

2025-523802-34-00 Immune-Mediated Thrombotic Thrombocytopenic Purpura
COLOMBE - A multicentre, single arm, phase 1/2 study, aiming to assess the safety and efficacy of nivolumab and imiquimod combination in vul… Pending

2025-524759-29-00 Vulvar Squamous Cell Carcinoma (VSCC) patients
A PHASE IB/II STUDY TO EVALUATE SAFETY AND EFFICACY OF BEXMARILIMAB IN COMBINATION WITH DOXORUBICIN IN METASTATIC SOFT-TISSUE SARCOMA (BEXAR… Pending

2025-525144-18-00 Advanced or metastatic histologically confirmed soft ti
A clinical trial of ifinatamab deruxtecan in people under age 18 who have certain types of cancer (MK-9999-01D) Recruiting

2025-522339-32-00 Neoplasm malignant 2026-06-30
A Randomized Phase 1 / 2 Trial Aiming to Restore UNC13A Function in People living with ALS: FUNCtion ALS Recruiting

2025-523111-11-00 Amyotrophic lateral sclerosis 2026-06-30
A Phase 1b/2 Study to Evaluate NB-4746 in Participants with Amyotrophic Lateral Sclerosis. Recruiting

2025-523939-18-00 Amyotrofic Lateral Sclerosis (ALS) 2026-06-23
Trial to study the safety and pharmacokinetics of ODM-212 combined with existing cancer treatments Recruiting

2025-524620-22-00 Neoplasms benign malignant and unspecified (incl. cysts 2026-06-22
Phase I/II combination umbrella trial in progressive/relapsed/refractory pediatric low-grade glioma (pLGG) (EPILOGUE) Recruiting

2024-516896-34-00 progressive/relapsed/refractory pediatric low-grade gli 2026-06-17
A clinical study of MK-1045 in people with non-Hodgkin lymphoma (MK-1045-008) Recruiting

2025-523005-15-00 Non-Hodgkin Lymphoma 2026-06-15
A Phase 1b/2, Multicenter, Randomized, Double-blind, Placebo-controlled Study of IM-101 in Adult Participants with Generalized Myasthenia Gr… Recruiting

2025-522406-20-00 Generalized Myasthenia Gravis and Ocular Myasthenia Gra 2026-06-15
A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally… Recruiting

2025-523524-53-00 ADVANCED OR METASTATIC RENAL CELL CARCINOMA 2026-06-12
Study to assess how safe and effective is HRX215 in participants who underwent minor and major liver surgery due to colon carcinoma metastas… Recruiting

2025-523630-59-00 colon carcinoma metastases 2026-06-12
HOVON 178 WM: Treatment of Waldenstrom’s macroglobulinemia with epcoritamab if the disease comes back during or after previous treatment Recruiting

2025-522295-91-00 relapsed or refractory Waldenstrom’s macroglobulinemia 2026-06-05
A Basket Trial of PM54 in Combination With Immunotherapy in Adult Participants With Advanced Malignancies Recruiting

2025-523774-16-00 Advanced malignancies 2026-06-03
A Study of YL201 in Combination with Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors Recruiting

2025-523742-27-00 Advanced solid tumors 2026-04-28
MATRIX-IPC 2022-029 A phase I/II study evaluating Tuvusertib (M1774), an ATR Inhibitor, in combination with fulvestrant in hormone receptors… Recruiting

2023-507485-10-00 advanced breast cancer 2026-04-21
A study to test the safety and disease progression following YTB323 (rapcabtagene autoleucel) administration in participant with progressive… Recruiting

2024-514006-31-00 Non-active Progressive Multiple Sclerosis (PMS) 2026-04-16
A clinical study of MK-1084 with other treatments for non-small cell lung cancer (MK-3475-01F) Recruiting

2024-512248-47-00 Non-small Cell Lung Cancer (NSCLC) 2026-04-15
A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies Recruiting

2024-516476-15-00 Advanced gastrointestinal stromal tumor (GIST) 2026-03-04
A study of belumosudil in children with chronic graft versus host disease (schoolROCK). Recruiting

2024-511508-18-00 Chronic graft versus host disease. 2026-01-05