Phase I/II – Other

643 trials 280 recruiting

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Inhibiting BCL-2 at the start of HIV treatment to reduce the HIV reservoir in people living with HIV Recruiting

2025-521841-26-00 HIV-1 infection 2026-02-20
Single-centre clinical trial investigating safety and tolerability of repeated administrations of increasing doses of nebulised SS0331 in he… Recruiting

2025-523875-48-00 Chronic airway infections 2026-02-17
A clinical trial to learn about the effects of DZR123 and JSB462 given together in men with advanced prostate cancer that has stopped respon… Recruiting

2025-521880-10-00 Metastatic castrate resistant prostate cancer (mCRPC) 2026-02-16
A clinical study of new treatments given with enfortumab vedotin and pembrolizumab in people with urothelial cancer (MK-3475-04D) Recruiting

2025-522253-19-00 Urothelial carcinoma 2026-02-11
TulmiSTAR-02: Phase I/II open-label study of tulmimetostat in combination with darolutamide vs. darolutamide, and tulmimetostat with abirat… Recruiting

2025-521873-15-00 Metastatic hormone-sensitive prostate cancer 2026-02-09
Phase 1/2 Study of PYX-201 in Combination with Pembrolizumab in Advanced Solid Tumors Recruiting

2025-521828-30-00 Advanced Solid Tumors 2026-01-27
A clinical study to test if an investigational treatment called BNT314 when used in combination with another investigational treatment pumit… Recruiting

2025-521768-36-00 Metastatic colorectal cancer 2026-01-27
An open label, phase I/II study investigating the safety and efficacy of the bispecific T-cell engaging antibody cizutamig (BCMAxCD3) in pat… Recruiting

2025-522857-20-00 Severe, treatment refractory primary Sjögren’s disease 2026-01-22
Phase 1b/2a Study to Evaluate Mezigdomide in Combination with Elranatamab in Relapsed and/or Refractory Multiple Myeloma Recruiting

2025-522090-11-00 Relapsed or Refractory Multiple Myeloma (RRMM) 2026-01-22
A phase I/II study of CAR-T cells in AutoiMmune disease resistant to B cell Abrogation - CARAMBA Recruiting

2025-521530-28-00 Progressive systemic autoimmune disease resistant to B 2026-01-19
A Study of Disitamab Vedotin in Adults With HER2 Expressing Advanced Breast Cancer Recruiting

2025-521003-52-00 HER2 Expressing Advanced Breast Cancer 2025-12-19
A study to find how well budoprutug (TNT119) works and how safe it is in participants with immune thrombocytopenia Recruiting

2024-519745-30-01 Immune Thrombocytopenia (ITP) 2025-12-19
To compare the Safety and activity of GDC-4198 Alone and in Combination with Giredestrant against Abemaciclib and Giredestrant in Participan… Recruiting

2025-521128-31-00 Locally Advanced or Metastatic Estrogen Receptor-Positi 2025-12-18
Guanabenz in VWM: extension study Recruiting

2024-518834-95-02 Vanishing white matter 2025-12-08
A clinical study to test if an investigational treatment called BNT326 is safe and potentially beneficial when used alone or in combination … Recruiting

2024-517261-16-00 Advanced solid tumors 2025-12-05
A Phase 1b/2 study of GSK5764227 in combination with Standard of Care (SoC) or other agents in participants with advanced solid tumors Recruiting

2025-522274-37-00 Neoplasms 2025-12-03
CASPONEB - Phase II safety lead-in randomized blind placebo controlled clinical trial : efficacy and safety of caspofungin aerosols for the … Recruiting

2023-508861-34-00 Pneumocystis pneumonia 2025-12-02
Prospective cohort involving repeated medical PET-CT imaging with a new radiotracer (FAPI) Recruiting

2024-512467-31-00 Non-metastatic Pancreatic ductal adenocarcinoma 2025-12-02
A Study of the Long-Term Safety and Efficacy of VX-670 in Patients With Myotonic Dystrophy Type I Recruiting

2024-517983-47-00 Myotonic Dystrophy 2025-11-25
The headache-inducing effects of cilostazol in men and women with migraine without aura Recruiting

2025-521520-29-00 Migraine 2025-11-21
TARLATEM : Combination of TARLAtamab and TEMozolomide in patients with central nervous system tumors. A multicenter, open-label Phase I/II t… Recruiting

2023-510568-11-00 High grade brain tumors 2025-11-18
Longitudinal study with positron emission tomography using [18F]PI-2620 in primary tauopathies. Proof-of-concept study Recruiting

2025-522826-11-00 Corticobasal syndrome (CBS) 2025-11-06
TransBronchial Needle injection of Tremelimumab in early-stage NSCLC patients (TALENT) Recruiting

2024-511878-67-00 Non small cell lung cancer 2025-11-03
A Phase 1b/2, Study of I-DXd in Combination with Atezolizumab with or without Carboplatin in First-line ES‑SCLC Recruiting

2023-509629-36-00 Extensive-stage Small Cell Lung Cancer (ES-SCLC) 2025-10-29