Phase I/II – Other

643 trials 280 recruiting

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New therapeutic approach to Toxic Epidermal Necrolysis (TEN) using anti-CD38+ antibodies in the active phase of the disease – Phase I/II stu… Pending

2024-512164-63-00 Toxic Epidermal Necrolysis
PET imaging For eaRly predictiOn of respoNse to neoadjuvanT tReatment in lUNg caNcER Pending

2025-524791-30-00 Non small cell lung cancer
The PACMAN-Hu19 trial: a phase I/II study with locally produced CD19-targeted CAR T-cell therapy Pending

2023-507597-40-00 B-cell precursor ALL
Phase II Randomized Clinical Trial of quinacrine versus metronidazole in resistant giardiasis in children: Quin4Kids Pending

2023-510227-30-00 Intestinal giardiasis
ABT-199 (Venetoclax) and Purine analogues as Novel Oral Drug Combination for Treatment of Relapsed/Refractory Acute Myeloid Leukemia (ApoAML… Pending

2024-510717-15-00 Acute myeloid leukemia
A study aimed at Optimise and Personalise Immunological Therapy of relapsed chronic lymphocytic leukaemia patients (OPTIC) Pending

2024-513917-11-01 Adult patients with chronic lymphocytic leukemia/small
DORAL Pending

2024-513941-35-00 HIV Disease
Low-grade UTUC Treated With Nadofaragene Firadenovec Administered to the Renal Pelvis (LUNAR) Pending

2024-514360-70-00 Low-grade upper track urothelial carcinoma (LG-UTUC)
Changes in the tumour microenvironment after intravenous or intradermal administration of anti-CTLA-4 in combination with anti-PD1 treatment… Pending

2024-516545-39-01 unresectable stage III – IV melanoma
A 6-Month, Randomized, Double-Blind Study to Evaluate the Effect of Dapagliflozin on EChOcardiographic Measures of CarDiac StructurE and Fun… Pending

2024-517040-65-02 Chronic kidney disease
Phase 1/2 evaluating the addition of venetoclax to standard 3+7 and midostaurin induction treatment in patients with FLT3-mutated Acute Myel… Pending

2024-517130-17-00 FLT3-mutated Acute Myeloid Leukemia
Phase 1 (sequential)/2a (parallel), double-blind, multicenter, randomized, controlled study to evaluate the safety and immunogenicity of two… Pending

2024-517396-20-00 Sarbecoviruses disease
CHEMOKINE RECEPTOR CXCR4-DIRECTED THERANOSTICS OF ADVANCED LYMPHOPROLIFERATIVE CANCERS BY RADIOPEPTIDE-BASED IMAGING AND THERAPY: THE COLPRI… Pending

2024-517639-35-00 Non-Hodgkin lymphomas (NHL)
Ventilation/Perfusion PET/CT with Galligas and 68Ga-MAA for regional lung function assessment after pulmonary embolism Pending

2024-518293-13-01 Pulmonary embolism
A study to investigate WEF-001 in patients with Advanced KRAS-Mutant Solid Tumours. Pending

2024-518644-21-01 Advanced KRAS- Mutant Solid Tumours
Scar Remodeling after Burn Injury using Adipose-derived Allogeneic Stem Cells Pending

2024-519160-41-00 Hypertrophic scarring.
Open-label clinical phase 1/2 study to assess the safety and efficacy of the SpectraCure P18 System and verteporfin for injection for the tr… Pending

2024-519658-35-00 Primary localised prostate cancer
A Phase Ib/II Open-Label, Multicentre Platform Study Evaluating Novel Combinations in Participants with Advanced or Metastatic Non-Small Cel… Pending

2024-519786-22-01 metastatic non-small cell lung cancer (NSCLC)
Clinical trial of selinexor plus gemcitabine in selected advanced soft-tissue sarcomas Pending

2024-520318-23-00 Patients with advanced soft-tissue sarcoma (leiomyosarc
Clinical Application of the Androgen Receptor Inhibitor Darolutamide to Upregulate the Prostate-Specific Membrane Antigen (PSMA) Protein Exp… Pending

2025-520482-52-03 Prostate cancer
The use of [68Ga]Ga-FAPI PET/MRI in assessing disease activity in patients with Graves’ orbitopathy Pending

2025-521163-12-01 Graves' Orbitopathy
Sequential Chemotherapy regimen with vinorelbine and cisplatin plus PET-guided stereotactic ablative radiotherapy (SABR) for castration- and… Pending

2025-521551-23-01 prostate cancer
A phase 1/2 study of subcutaneous blinatumomab administration in children with R/R and MRD+ B-ALL Pending

2025-521671-31-00 Relapsed/Refractory (R/R) and Minimal Residual Disease
Phase 1/2 multicenter, two-arms, open-label, dose-escalation study of IDP-121 in combination with chemotherapy in patients with relapsed sma… Pending

2025-521902-17-00 Unresectable/metastatic Small cell Lung Cancer (SCLC)