Phase I/II – Other

643 trials 280 recruiting

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A Study Evaluating the Efficacy and Safety of Risvutatug Rezetecan in Participants With Advanced Sarcomas (EMBOLD Sarcoma-202) Recruiting

2025-523997-18-00 Sarcoma 2026-06-29
A study to assess the long-term safety and clinical activity of mRNA-3927 in participants previously enrolled in the mRNA-3927-P101 study Recruiting

2022-502911-12-00 Propionic Acidemia 2026-06-26
A Double-Blind, Randomized, Placebo-Controlled Study to Investigate the Safety and Efficacy of Aritinercept, a Dual BAFF/APRIL Inhibitor, in… Recruiting

2025-525127-27-00 Generalized Myasthenia Gravis 2026-06-08
Multi-centre Phase 1/2 study testing LB-208 for adults with relapsed/refractory AML or high-risk MDS Recruiting

2025-523396-38-00 Relapse or refractory (r/r) acute myeloid leukaemia (AM 2026-05-29
A Study to Test a New Drug in Adults With Moderate to Severe Ulcerative Colitis Recruiting

2025-524719-35-00 Ulcerative Colitis 2026-05-22
Exploratory study on the effect of Rimonabant on hand function in patients with spinal cord injury (RIMOHANDOPEN) Recruiting

2025-524279-22-00 Spinal cord injury 2026-05-22
A Phase 1/2 Study of Pumitamig alone or in Combination with Ipilimumab in First-Line HCC Recruiting

2025-523602-33-00 Advanced or unresectable Hepatocellular Carcinoma (HCC) 2026-05-13
Dual wavelength fluorescence imaging using fluorescently labelled adalimumab and risankizumab for visualizing drug targeting in Inflammatory… Recruiting

2025-521420-30-00 Inflammatory Bowel Disease (IBD) 2026-05-08
A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants with Multiple Myeloma Receiving Etentamig (ABBV-… Recruiting

2024-515770-27-00 Multiple Myeloma 2026-04-27
A Single-center, Prospective, Non-randomized, Open, Pilot Study Evaluating the Safety and Performance of the Extroducer® Infusion Catheter S… Recruiting

2025-524733-11-00 Unresectable Locally Advanced Pancreatic Cancer 2026-04-22
A clinical study to investigate the efficacy and safety of an investigational combination therapy with BNT324 and BNT327 in patients with ad… Recruiting

2024-520238-31-01 Advanced Lung Cancer 2026-04-20
Sodium selenite in patients with advanced carcinoma: SECAR 1c Recruiting

2025-522798-13-00 Advanced carcinoma 2026-04-17
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients with Advanced Liver Cancers (M… Recruiting

2023-506611-17-00 Advanced liver cancers 2026-04-16
MB-CART2019.1 in refractory MS Recruiting

2024-517601-82-00 refractory Multiple Sclerosis 2026-04-01
A clinical trial to learn about the effects of AMO959 given with AAA617 and an androgen receptor pathway inhibitor (ARPI) in adults with PSM… Recruiting

2025-521859-23-00 PSMA-positive mCRPC with prior exposure to at least one 2026-03-31
A Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BCX17725 Recruiting

2025-521973-16-00 Netherton Syndrome 2026-03-31
Pharmacokinetics, safety, and efficacy of fisetin - A phase I and pilot phase IIa study Recruiting

2023-506284-34-00 Healthy 2026-03-24
Single-center phase I/IIa study with CART cells produced using the anti-CD19 transposon technique (TranspoCART19) for patients with CD19+ ac… Recruiting

2025-522673-11-00 refractory or resistant CD19+ acute lymphoblastic leuke 2026-03-17
A clinical trial to test if an investigational combination therapy with BNT326 and BNT327 is safe and potentially beneficial for people with… Recruiting

2024-519344-32-00 Non-small Cell Lung Cancer 2026-03-16
A clinical study of MK-3120 in people with bladder cancer (MK-3120-003) Recruiting

2025-520467-40-00 High-risk non-muscle invasive bladder cancer (NMIBC) wi 2026-03-16
Guttmann NeuroRecovery – Feasibility, safety and efficacy of intrathecal Wharton's jelly-derived mesenchymal stem cells and transcutaneous s… Recruiting

2025-521877-14-00 Traumatic spinal cord injury 2026-03-11
A Study Testing a New Targeted Drug (TUB-040) in combination with Standard Chemotherapy for Women with Ovarian Cancer Recruiting

2025-524691-33-00 High-grade epithelial serous or endometrioid epithelial 2026-03-09
A clinical study to find the optimal dose of an investigational treatment called BNT323 when used in combination with another investigationa… Recruiting

2024-517979-20-00 Advanced Breast Cancer Metastatic Breast Cancer 2026-03-04
An open label, phase I/II study investigating the safety and efficacy of a CD3/CD20 bispecific T-cell engager therapy in patients with activ… Recruiting

2025-522853-21-01 Active, treatment refractory, ANCA-IgG-positive associa 2026-02-27