Nutritional and Metabolic Diseases

441 trials 157 recruiting

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Effect of high-dose vitamin D on 28-day mortality in adult critically ill patients with severe vitamin D deficiency Recruiting

2024-514556-32-00 Adult critically ill patients with severe vitamin D def 5 2017-02-15
Desferal administration to improve the impaired reaction to hypoxia in diabetes (DESIRED) - A randomised, double-blind, placebo-controlled, … Recruiting

2024-519562-48-00 The study will investigate the effect of deferoxamine o 4 2017-01-12
Weight loss in people living with overweight or obesity following treatment with cagrilintide Ended

2024-519530-24-00 Overweight and obesity 5 2025-10-31
Weight loss in people living with overweight or obesity and type 2 diabetes following treatment with cagrilintide Ended

2024-519531-41-00 Overweight and obesity 5 2025-10-31
APOLLO: A Randomized, Double-Blind, Placebo-Controlled Study of Bitopertin to Evaluate the Efficacy, Safety, and Tolerability in Participant… Ended

2024-520407-27-00 X-Linked Protoporphyria (XLP) 5 2025-10-23
A Study to Compare Different Doses of RO7795081 with a Placebo or Semaglutide in People with Type 2 Diabetes Ended

2024-520322-11-00 Type 2 Diabetes Mellitus (T2D) 4 2025-09-29
A study to test whether vicadrostat in combination with empagliflozin helps people with chronic kidney disease Ended

2024-518457-42-00 chronic kidney disease 4 2025-08-28
J2A-MC-GZPO: A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes J2… Ended

2025-521098-14-00 GZP1, GZP2: Obesity, Overweight GZP2: Type 2 Diabetes 5 2025-08-15
A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants with PMM2-CDG Ended

2024-520109-37-00 PMM2-CDG 4 2025-07-09
A Trial to Study the Safety and Efficacy of a New Drug Combination for Weight Loss While Maintaining Muscles Ended

2024-519561-22-00 Obesity 4 2025-07-07
A study to see the effect of NNC0194-0499 alone or in combination with semaglutide on blood sugar control in people living with type 1 diabe… Ended

2024-519533-38-00 Diabetes mellitus type 1 3 2025-06-24
A Study to Learn How Different Amounts of the Study Medicine Called PF-07999415 are Tolerated and Act in the Body in Healthy Adults Ended

2024-520380-13-00 CCI 1 2025-06-17
Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight (MARIT… Ended

2024-515523-11-00 Chronic Weight Management 5 2025-06-09
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040) A Study of Orforglipron (LY3502970) in Adolescent Partici… Ended

2024-514081-40-00 Obesity, Overweight 5 2025-06-06
Assessing the safety, tolerability, and effectiveness of crofelemer in people with the intestinal disease Microvillus Inclusion Disease (MVI… Ended

2024-512845-18-00 Microvillous Inclusion Disease (MVID) 4 2025-06-03
Efficacy and Safety of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight (MA… Ended

2024-515524-36-00 Chronic Weight Management 5 2025-05-30
Clinical trial to evaluate whether personalized treatment based on genetics improves type 2 diabetes control Ended

2025-520686-46-00 Type 2 Diabetes Mellitus 6 2025-05-15
A research study comparing how well different doses of the medicine NNC0519-0130 can reduce kidney damage in people living with chronic kidn… Ended

2024-510846-15-00 Chronic Kidney Disease, with or without Type 2 diabetes 4 2025-04-14
Evaluation of the safety and efficacy of an advanced therapy medicinal product containing live ASCs in the treatment of diabetic foot syndro… Ended

2024-518533-29-00 DIABETIC FOOT ULCER 4 2025-03-05
STEP TEENS Weight Maintenance: A research study on how well semaglutide helps teenagers with excess body weight to lose weight and maintain … Ended

2023-508055-40-00 Obesity 6 2025-02-18
FINESSE: Research on improving albuminuria in patients with chronic kidney disease through the use of finerenone and semaglutide. Ended

2023-506434-69-00 Chronic Kidney Disease 4 2025-02-11
A research study to look into the long-term effect on weight loss of CagriSema in people with obesity Ended

2024-512144-39-00 Obesity 5 2025-01-22
A research study to investigate the effects of CagriSema compared to placebo in people with type 2 diabetes and painful diabetic peripheral … Ended

2023-509662-38-00 Type 2 diabetes and painful diabetic peripheral neuropa 4 2025-01-22
A Double-blind, Placebo-controlled, Randomized Study to Evaluate the Efficacy and Safety of KBP-336 as an Adjunct to Diet and Exercise in Ob… Ended

2024-517264-27-00 Knee osteoarthritis 4 2024-12-13