Nutritional and Metabolic Diseases

441 trials 157 recruiting

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Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH (ENLIGHTEN-Cirrhosis) Recruiting

2023-510395-31-00 Metabolic Dysfunction-Associated Steatohepatitis (MASH) 5 2024-10-30
A trial to test the effect of obicetrapib/ezetimibe on coronary plaque characteristics on coronary computerized tomography angiography in pe… Recruiting

2023-508475-36-00 Atherosclerotic Cardiovascular Disease 5 2024-10-29
Controlled and randomized clinical trial of the use of plasma rich in growth factors (PRGF) in the treatment of foot ulcers in diabetic pati… Recruiting

2023-504275-24-01 Foot ulcers in diabetic patients with peripheral arteri 6 2024-10-24
An interventional, multi-center, randomized, double blinded, placebo controlled study to investigate semaglutide add-on treatment for metabo… Recruiting

2023-506109-20-00 Metabolic control in antipsychotic-using patients 5 2024-10-19
Effect of Treatment with Finerenone on Cardio-Renal Target Organ Damage in Patients with Type 2 Diabetes – A Randomized Trial Recruiting

2023-504446-58-00 Type 2 diabetes, chronic kidney disease 6 2024-10-15
TOLEDDO: Effect of weekly GLP1 agonist treatment in "double diabetes": a randomized, open-label study Recruiting

2024-514906-30-00 "double diabetes" 5 2024-10-14
Kidney ABC Recruiting

2024-511484-29-00 Diabetic kidney disease 4 2024-10-09
A Long-Term Study with GLM101 in Patients with PMM2-CDG Recruiting

2024-512171-12-00 PMM2-CDG 4 2024-09-27
A STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF COR-1389 Recruiting

2024-514853-31-00 Obesity / Right heart failure (healthy participants) 1 2024-09-10
Safety and efficacy of oral semaglutide in hyperglycaemic patients after renal transplantation Recruiting

2023-504159-29-01 Hyperglycaemia after renal transplantation 4 2024-09-03
Effect of Roxadustat on Cardiometabolism Recruiting

2023-508183-29-00 Risk factors of cardiovascular disease 6 2024-08-07
PILOT STUDY OF THE EFFECT OF A SUBSTANCE P ANTAGONIST, APREPITANT, ON THE SECRETION OF ALDOSTERONE IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA … Recruiting

2024-514837-39-00 Patients with obstructive sleep apnea syndrome with art 5 2024-07-01
Prospective, multicenter, open-label study to evaluate the efficacy of esmolol in the early identification of cardiovascular disorders induc… Recruiting

2024-514880-25-00 Patients with cardiovascular alterations induced by cir 5 2024-06-27
Grafalon®therapy within 12 weeks of Type 1 diabetes (T1D) diagnosis in children and young adults to prevent the loss of residual beta cell f… Recruiting

2023-508514-42-00 Type 1 diabetes 4 2024-06-04
The effect of oral Semaglutide on bone turnover in patients with T2D: a randomized placebo-controlled clinical trial (SOBER II) Recruiting

2023-505959-45-00 Type 2 diabetes 4 2024-05-31
Anti-viral action against Type 1 diabetes autoimmunity GPPAD-05-AVAnT1A Recruiting

2023-507348-35-00 Risk for Type 1 Diabetes 6 2024-05-30
PROMISE Recruiting

2023-505626-34-01 Chronic kidney disease 6 2024-05-16
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3938577 in Healthy Participants and Participants wit… Recruiting

2023-510365-10-00 Type 1 Diabetes Mellitus 3 2024-04-29
Study to learn about the safety of fazirsiran and if it can help people with alpha-1 antitrypsin liver disease with mild liver scarring (fib… Recruiting

2023-504198-19-00 Alpha-1 Antitrypsin Deficiency-Associated Liver Disease 5 2024-04-18
FIT-HF - Effect of weight loss on physical and cardiac performance in patients with heart failure and obesity Recruiting

2023-503753-35-01 Obesity and Heart Failure with reduced Ejection Fraciti 4 2024-03-20
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of Efruxifermin in Subjects with Non-Cirrho… Recruiting

2023-505141-48-00 Fibrosis 5 2024-03-07
GLYCOGEN RESPONSE TO ENZYME REPLACEMENT THERAPY IN POMPE DISEASE Recruiting

2023-508000-37-01 Pompe Disease 6 2024-02-13
Effect of proton pump inhibitors on the structural integrity of endoscopic sleeve gastroplasty: a single-centre open-label, randomized, cont… Recruiting

2024-517679-18-00 obesity 6 2024-02-09
Frexalimab in preservation of endogenous insulin secretion compared to placebo in adults, adolescents and children on top of Insulin therapy… Recruiting

2022-500531-36-00 Type 1 diabetes mellitus 4 2024-02-02