Nutritional and Metabolic Diseases

441 trials 157 recruiting

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STEP Young: A research study on how well semaglutide helps children and teenagers with excess body weight lose weight Ended

2022-502922-41-00 Obesity and overweight 5 2023-07-03
Semmelweis Lipid Center for High-risk Patients Ended

2024-519058-35-00 primary hypercholesterolaemia (heterozygous familial an 6 2023-05-30
A Study to Determine the Effect of Triheptanoin Compared with Even-chain MCT on MCEs in Pediatric Patients with LC-FAOD Ended

2023-509809-76-00 Long-chain Fatty Acid Oxidation Disorders (LC-FAOD) 5 2023-02-28
REDEFINE 3: A research study to see the effects of CagriSema in people living with diseases in the heart and blood vessels Ended

2023-506924-94-00 Cardiovascular disease 5 2023-02-28
A clinical study of a virus transferring the gene for human Ornithine Transcarbamylase (OTC) in patients 12 years of age and older with late… Ended

2024-514337-38-00 Late-onset Ornithine transcarbamylase (OTC) deficiency 5 2023-01-24
A Study of Tirzepatide (LY3298176) on the Reduction of Morbidity and Mortality in Adults With Obesity (SURMOUNT- MMO) Ended

2022-501744-15-00 Obesity, Overweight 5 2023-01-23
A Phase 3 Multi-Center Study to Evaluate the Safety and Efficacy of Subcutaneous Injections of Pegvaliase in Adolescent Subjects (Ages 12- 1… Ended

2024-510875-39-00 Phenylketonuria (PKU) 5 2022-10-25
A research study to see how well CagriSema helps people with excess body weight lose weight Ended

2023-506929-11-00 Overweight and obesity 5 2022-10-17
A study to learn how well finerenone works; how safe it is; how it moves into, through, and out of the body; and the effects it has on the b… Ended

2023-504884-17-00 Proteinuria 5 2022-02-04
A clinical study to assess the efficacy and safety of lanifibranor followed by an active treatment extension in adult patients with non-cirr… Ended

2023-508248-23-00 Non-alcoholic steatohepatitis (NASH) 5 2021-11-26
Recent-Onset Type 1 Diabetes Extension Study Evaluating the Long-Term Safety of Teplizumab Ended

2024-516543-26-00 Type 1 Diabetes Mellitus 5 2021-07-23
A research study on how well liraglutide works in children with obesity Ended

2023-508504-38-00 Obesity 5 2021-03-01
Study for patients with Primary Hyperoxaluria to evaluate the Long-Term Safety and Efficacy of DCR-PHXC Solution for Injection Ended

2024-512260-54-00 Primary Hyperoxaluria 5 2019-08-20
A research study to look at how semaglutide compared to placebo affects diabetic eye disease in people with type 2 diabetes (FOCUS) Ended

2023-506827-26-00 While it is well-established that long-term good glycae 5 2019-05-02
A study to determine the long-term safety and tolerability of oral lucerastat in adult subjects with Fabry disease Ended

2024-513884-20-00 Fabry disease 5 2019-03-13
The effect of strict blood glucose control within normal fasting ranges, with insulin adjusted according to the Leuven algorithm, in adult c… Ended

2023-510358-17-00 Hyperglycemia in critically ill patients (stress hyperg 5 2018-09-01
Research study to evaluate the experimental drug ferumoxytol, to see how well it works for children with chronic kidney disease (CKD) and ir… Ended

2024-516263-92-00 Iron Deficiency Anemia (IDA) in Pediatric Subjects with 5 2018-06-25
A Double-blind, Placebo-controlled, Multiple-Dose, 2-Period Crossover Study to Evaluate the Effect of Steady-state AZD6793 on the Steady-sta… Halted

2025-522551-25-00 Type 2 Diabetes Mellitus 3 2026-01-14
Bioequivalence Study of Empagliflozin Ended

2026-525434-33-00 Not applicable (submitted trial is a BE study in health 2 2026-04-07
A study investigating the safety of RO7795074, a new compound that may potentially be used in the treatment of type 1 diabetes, and the effe… Ended

2025-521921-34-00 Overweight or Obese (otherwise healthy) 3 2025-12-19
Investigating the pharmacokinetics of petrelintide using different drug product concentrations in participants with a BMI ≥27.0 kg/m2 Ended

2025-520598-38-00 Weight reduction 3 2025-12-17
A research study of a new medicine NNC0363-1063 in participants with type 1 diabetes Ended

2025-521593-33-00 Diabetes type 1 3 2025-12-03
A Study Investigating the Safety and Absorption of Different Administration forms of RO7795074, a New Compound that may Potentially be Used … Ended

2025-521888-13-00 Overweight or Obese (otherwise healthy) 3 2025-12-02
A study to find out whether the medication pasireotide is absorbed and processed the same way when given under the skin using either a reusa… Ended

2024-519165-22-00 Post-bariatric hypoglycaemia 3 2025-11-04