Nervous System Diseases

1,005 trials 421 recruiting

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The Anaesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury (KETA-BID) Recruiting

2024-515315-22-00 subarachnoid hemorrhage, intracerebral hemorrhage, trau 6 2023-09-15
Multicenter, randomized, double-blind, and placebo-controlled clinical trial to assess the efficacy and safety of donepezil versus placebo i… Recruiting

2024-510959-35-00 Parkinson's disease 4 2023-09-07
TCRaß+CD19+ depleted haploidentical stem cell transplantation followed by immunotherapy in patients with relapsed/resistant high-risk neurob… Recruiting

2024-519089-32-02 Patient affected by high risk Neuroblastoma relapsed or 4 2023-08-29
Perineural injections of incobotulinumtoxin-A for diabetic neuropathic pain of the lower extremities: A double-blind, randomized, placebo-co… Recruiting

2022-500727-68-01 Diabetic neuropathic pain 4 2023-08-07
A 20-Week Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of EPX-100 (Clemizole Hydrochloride) as Adjunctive Therapy in Chil… Recruiting

2024-518628-57-00 Dravet syndrome 5 2023-08-01
Effect of ozanimod on meningeal inflammation and glial activation in Multiple Sclerosis: one year phase 4 experimental study Recruiting

2024-518859-27-00 Relapsing Multiple Sclerosis (relapsing-remitting, rela 6 2023-07-06
Exploring the effect of a novel therapy on chronic intrathecal inflammation in patients with active progressive multiple sclerosis Recruiting

2024-512283-65-00 patients with secondary progressive MS 6 2023-05-29
Evaluation of diagnostic performances of 18F-FDOPA PET KInetics as biomarkers for the improvement of care of MRI Non-contrast enhanced Gliom… Recruiting

2022-501688-42-00 Low Grade Glioma 5 2023-05-24
Study to evaluate the efficacy and safety of low-dose aspirin as an add-on to standard therapy in patients with bipolar disorder (ASPIRIN BD… Recruiting

2024-516584-86-00 Bipolar Affective Disorder 4 2023-05-19
An adaptive, Phase 2, double-blind, randomized, placebo-controlled, multicenter study to evaluate the safety, tolerability, immunogenicity, … Recruiting

2022-500292-31-00 Early stages of idiopathic Parkinson's Disease 4 2023-05-12
Migraine and High Flow Oxygenotherapy at the Emergency Department (MiOx) Recruiting

2022-501133-23-00 MIGRAINE 4 2023-05-11
Clinical trial to see the effect and safety of botulinum toxin type A with doses adapted to patients with severe spasticity Recruiting

2024-517668-51-01 brain damage oriented spasticity 6 2023-05-03
Acute Subcutaneous Semaglutide in Acute Ischemic Stroke (ASSET Trial) Recruiting

2022-501072-25-02 Ischemic Stroke 4 2023-04-12
Long-Term Open-Label Study to Assess the Safety and Efficacy of Vatiquinone in Patients With Friedreich Ataxia Recruiting

2024-516505-23-00 Friedreich ataxia 5 2023-03-22
A study with eptinezumab in children and adolescents (6 to 17 years) with chronic or episodic migraine (REJOIN) Recruiting

2022-502917-27-00 Migraine 5 2023-03-07
A RANDOMIZED DOUBLE BLIND, PLACEBO-CONTROLLED NATIONAL MULTICENTER PHASE 3 TRIAL TO EVALUATE THE EFFICACY OF AZATHIOPRINE FOR THE PREVENTION… Recruiting

2022-500520-30-00 neurology 5 2023-03-01
Prospective, open-label, non-randomized, single-arm, dose titration study to investigate the efficacy and safety of IncobotulinumtoxinA in c… Recruiting

2024-518447-38-00 multifocal spasticity of the upper and lower limb due t 4 2023-02-10
Placebo controlled study to assess the efficacy and safety of rapamycin in drug resistant epilepsy associated with tuberous sclerosis comple… Recruiting

2024-515937-13-00 tuberous sclerosis complex, epilepsy, organ tumors asso 5 2023-02-07
A phase 1/2a, open-label trial to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending doses o… Recruiting

2024-514328-18-00 Spinocerebellar ataxia types 1, 3 and Huntington's dise 7 2022-12-06
DMT in healthy subjects Recruiting

2024-518020-68-00 Stroke 3 2022-11-15
A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neu… Recruiting

2024-510990-21-00 Mucopolysaccharidosis Type II [MPS II] 10 2022-11-11
A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine (PROSPECT-2) Recruiting

2024-510656-13-00 Migraine 5 2022-11-08
Research study to assess the potential of masupirdine in patients with agitation symptoms associated with memory loss Recruiting

2024-513835-25-00 Agitation with Dementia of the Alzheimer's Type 5 2022-10-27
Efficacy and Safety Study of Nipocalimab for Adults with CIDP Recruiting

2023-508425-28-00 Chronic Inflammatory Demyelinating Polyneuropathy 4 2022-10-24