Neoplasms

3,880 trials 1,551 recruiting

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Sequential Chemotherapy regimen with vinorelbine and cisplatin plus PET-guided stereotactic ablative radiotherapy (SABR) for castration- and… Pending

2025-521551-23-01 prostate cancer 9
A First-In-Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination with Cemiplimab Works in Adult Participan… Pending

2025-523399-22-00 Advanced Solid Tumours 7
Phase I-II prospective trial, multicenter, open label, exploring the combination of Trabectedin plus RAdiotherapy in Soft Tissue Sarcoma pat… Pending

2024-518199-30-00 Soft tissue sarcoma patients 9
Guided by Light: Optimizing Surgical Excision of Oral Cancer Using Realtime Fluorescence Imaging Pending

2024-512824-13-01 Oral cancer 7
A Phase II, Open-label, Multicenter Study Testing Teclistamab in Combination with Pomalidomide Administered in Alternative Fashion in Partic… Pending

2025-522114-23-00 Multiple myeloma (RRMM) 4
A study to evaluate the safety and efficacy of the tumor-targeting human antibody-cytokine fusion protein L19TNF plus standard temozolomide … Pending

2024-516357-46-00 Glioblastoma 9
A Phase Ib/II Open-Label, Multicentre Platform Study Evaluating Novel Combinations in Participants with Advanced or Metastatic Non-Small Cel… Pending

2024-519786-22-01 metastatic non-small cell lung cancer (NSCLC) 9
A trial to learn how well sonesitatug vedotin and capecitabine with or without rilvegostomig work and how safe they are in adults with cance… Pending

2024-519787-40-00 Gastric Cancer, Gastroesophageal Junction Adenocarcinom 5
A PHASE IB/II STUDY TO EVALUATE SAFETY AND EFFICACY OF BEXMARILIMAB IN COMBINATION WITH DOXORUBICIN IN METASTATIC SOFT-TISSUE SARCOMA (BEXAR… Pending

2025-525144-18-00 Advanced or metastatic histologically confirmed soft ti 9
SIL204-SL Treatment for Locally Advanced Pancreatic Cancer Pending

2025-525157-39-00 Non-Resectable Locally Advanced Pancreatic Cancer (LAPC 10
Pharmacokinetics, safety, and immunogenicity comparison of Bmab1700 and Opdivo® as adjuvant monotherapy in patients with melanoma Pending

2025-525158-20-00 Stage IIB/C, Stage III, or Stage IV Melanoma 1
A phase 1b study of an autologous dendritic cell immunotherapy in combination with anti-programmed death-1 treatment in patients with metast… Pending

2025-521577-13-00 metastatic non-small-cell lung cancer 1
A Phase 1/2 Study of Inhaled KB707 in Patients Pending

2025-522723-98-00 solid tumor 9
A Phase 1/2, Open-label Study of VS-7375, a KRAS G12D (ON/OFF) Inhibitor, as Monotherapy and in Combination, in Patients with Advanced KRAS … Pending

2025-523432-39-01 Advanced KRAS G12D-Mutant Solid Tumors 9
Phase 1/2 Study of BLU-451 in certain advanced cancers Pending

2022-502527-21-00 Advanced cancers with EGFR Exon20 insertions mutations 7
Study with IDE849 for patients with DLL3 positive cancer, including small cell lung cancer Pending

2025-523438-24-00 DLL3 Expressing Tumors Including Small Cell Lung Cancer 9
A Study to Learn about the Long-Term Health of Adult Participants from a Previous Study of a New Melanoma Treatment Pending

2024-517729-20-00 Melanoma 4
A clinical trial to learn how liver function affects the blood levels of DAK539 in people with advanced cancer Pending

2025-521001-40-00 Advanced Malignancies and Hepatic Impairment 3
Hyperprogression upon cemiplimab alone or with chemotherapy in PD-L1 ≥ 50% NSCLC: a biomarker guided phase 2 trial – HYPERBOLIC study Pending

2025-521583-35-00 non-small cell lung cancer (NSCLC) 4
A multicenter, multicohort, phase 2 platform trial to personalize second-line treatment intensity and targeting in HR-positive, HER2-negativ… Pending

2025-523460-21-00 Metastatic breast cancer 4
The ALPINE trial: a phase 1-2 study of intra-arterial [177Lu]Lu-PSMA-I&T for progressive or recurrent intracranial adult type diffuse gliom… Pending

2023-504696-24-00 Glioma (diffuse astrocytoma, oligodendroglioma or gliob 7
Adjuvant hepatic arterial infusion pump chemotherapy after resection of colorectal liver metastases in patients with a low clinical risk sco… Pending

2024-512850-10-00 Resectable colorectal rectal metastases without extrahe 5
EPITOME-1015-I: A phase I study to investigate the safety and tolerability of MDG1015 in patients with epithelial ovarian cancer, gastroesop… Pending

2024-516787-28-00 Epithelial Ovarian Carcinoma 1
ALASCCA-A randomized double-blind placebo-controlled study with ASA treatment in colorectal cancer patients with mutations in the PI3K signa… Pending

2024-513778-23-00 Colon and rectal cancer tumor stage II-III, tumor with 5