Neoplasms

3,876 trials 1,551 recruiting

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Phase I, double-blind, randomized, placebo-controlled study investigating the safety, tolerability and concentrations of the study product K… Not authorised

2023-503909-11-00 Ovarian cancer 1
A Phase 3, Randomized Study to Compare Nemtabrutinib Versus Comparator (Investigator’s Choice of Ibrutinib or Acalabrutinib) in Participants… Not authorised

2022-501697-19-00 Small Lymphocytic Lymphoma (SLL) / Untreated Chronic Ly 5
HER2 molecular imaging with 89Zr-trastuzumab PET/CT as a predictive biomarker for antibody-drug conjugate sequencing in patients with advanc… Not authorised

2024-516253-49-00 advanced/metastatic HER2-positive breast carcinoma 4
A Phase I Interventional Open-Label, Non-Randomized Dose-Escalation Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacody… Not authorised

2024-516660-28-00 Locally advanced, recurrent, or metastatic breast, gast 1
Open-label clinical phase 1/2 study to assess the safety and efficacy of the SpectraCure P18 System and verteporfin for injection for the tr… Pending

2024-519658-35-00 Primary localised prostate cancer 9
Phase II study of ficerafusp alfa in combination with nivolumab in patients with platinum-refractory head and neck squamous cell carcinoma w… Pending

2025-521437-88-00 head and neck squamous cell carcinoma 4
A Study Testing the Investigational Drug XmAb541 in people with Advanced Cancer Pending

2025-521981-90-00 Advanced Solid Tumors 1
F-18 PSMA-11 PET for Imaging and Staging of Hepatocellular carcinoma with Evaluation of Survival Pending

2023-508709-26-00 Hepatocellular carcinoma 4
A study to test different doses of BI 3923948 alone and in combination with an anti-PD-1 antibody in people with different types of advanced… Pending

2025-521438-27-00 advanced, unresectable and/or metastatic solid tumors 1
Clinical trial evaluating the biological activity of a new drug identified as prifetrastat (PF-07248144), combined with fulvestrant for the … Pending

2025-521982-29-00 Adult patients with advanced hormone receptor positive 4
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination with Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compare… Pending

2025-522563-15-00 Metastatic Pancreatic Ductal Adenocarcinoma; PDAC 10
Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults with Advanced Colorectal Cancer. Pending

2025-523984-39-00 Advanced Microsatellite Stable (MSS) Colorectal Cancer 4
A phase 2, single arm, open label, study on the safety and feasibility of Liver Isolated Oxaliplatin (LIOX) delivered via arterial access de… Pending

2025-523261-25-00 colorectal cancer 4
A multicentre, prospective, open-label study with [68Ga]Ga-ABY-025 PET-imaging to characterize HER2-expression and explore the therapy-predi… Pending

2024-512721-89-00 Breast Cancer 4
Phase II, open label, single arm, multicenter study to assess the activity and safety of ALectinib as NE O adjuvant therapy in patients with… Pending

2024-519106-12-00 Patients with anaplastic lymphoma kinase positive (ALK+ 4
A study investigating the safety and efficacy of academically-produced CAR T cells compared with standard treatment for patients with multip… Pending

2025-524876-43-00 relapsed/refractory multiple myeloma 5
Phase 1b/2 Trial of OMTX705, an Anti-Fibroblast Activation Protein Antibody-Drug Conjugate, in Combination with Carboplatin, Pemetrexed and … Pending

2025-521989-95-00 Advanced/Metastatic Non-squamous Non-Small Cell Lung Ca 9
FIDES: Focused Ultrasound-mediated Blood-Brain Barrier Opening In Pontine Diffuse Midline Glioma (DMG) to Enhance Systemic Therapy with Temo… Pending

2025-520814-78-00 Diffuse Midline Glioma, H3K27-altered 9
A First In Human Phase I Trial Evaluating safety, tolErability and ResponSe of [211At]At-Girentuximab (ATO-101™) in PatiEnts with Non-Muscle… Pending

2023-509729-33-00 Non-Muscle-Invasive Bladder Cancer (NMIBC) refractory 1
A Phase III study evaluating the efficacy of atezoliumab administration in addition to BCG (Bacillus Calmette-Guerin) for 1 year in patient… Pending

2024-517621-54-00 High-risk non-muscle invasive bladder cancer (NMIBC) af 5
A study of Mirdametinib in Infants and Toddlers under 24months of age with Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas… Pending

2025-522000-24-00 Neurofibromatosis Type 1 (NF1) Associated Plexiform Neu 3
Phase 1/2 evaluating the addition of venetoclax to standard 3+7 and midostaurin induction treatment in patients with FLT3-mutated Acute Myel… Pending

2024-517130-17-00 FLT3-mutated Acute Myeloid Leukemia 9
Moonlanding: A phase 2 study of pembrolizumab plus belzutifan, with or without lenvatinib, given before the main treatment for localized kid… Pending

2024-519673-18-00 Patients with localized renal cell carcinoma 4
A clinical trial to learn more about the effects of DJI136 in people with extensive-stage small cell lung cancer Pending

2025-523276-23-00 Extensive stage small cell lung cancer 7