Neoplasms

3,880 trials 1,551 recruiting

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French prospective randomised double blind study on aspirin versus placebo in resected colon cancer with PI3K mutation stage III or II high … Pending

2024-516007-16-00 Resected colon cancer with PI3K mutation stage III or I 5
Adjuvant Pembrolizumab in patients with early-stage triple negative breast cancer with residual disease after treatment with chemotherapy an… Pending

2025-524229-41-00 Triple negative breast cancer 5
RuxoTam; A phase II study to evaluate safety and efficacy of tamoxifen in combination with Ruxolitinib in patients with myelofibrosis Pending

2024-510926-19-00 Myelofibrosis 4
REGENOVAR: A Phase I/II Study of Ubamatamab Plus Carboplatin, Paclitaxel, and Bevacizumab as Salvage Therapy in Ovarian Cancer with Poor Res… Pending

2025-524232-20-00 Patients with poor prognostic ovarian cancers based on 7
A randomized phase II study of Pembrolizumab (MK-3475) as maintainance therapy in patients with unresectable stage III non-small cell lung … Pending

2024-514701-57-01 non Small Cell Lung Cancer 4
The Synergism Or Long Duration (SOLD) Study Pending

2024-512884-30-00 breast cancer 5
A phase 3 study of orelabrutinib in combination with rituximab plus bendamustine (BR) compared with BR in subjects with treatment-naїve mant… Pending

2025-524241-27-00 Treatment-naїve mantle cell lymphoma (MCL) 5
Optimizing subcutaneous FEntanyl titRation: RApid achievement of adequate exposure when treating cancer-Related paIn (FERRARI-study). Pending

2023-507355-30-00 Cancer pain 6
A Study to Evaluate the Safety and Tolerability of ARV-806 in Adults with Advanced Cancer that has the KRAS G12D Mutation Pending

2025-521062-10-00 KRAS G12D Mutated Advanced Solid Tumors 1
Trial assessing treatment in patients with advanced Lung Cancer and Interstitial Lung Disease Pending

2025-522790-10-00 Non Small Cell Lung Cancer 4
Mechanisms of Resistance to anti-PD-1 Therapy in cutaneous Squamous Cell Carcinomas: Impact of Tumor Cell Plasticity on Promoting Myeloid Su… Pending

2025-524255-32-00 Cutaneous squamous cell carcinoma (ccSCC) 4
Symbiotic-GI-13, A Study to Learn About the Study Medicine Called PF-08634404 as Monotherapy and Combination Therapy in Adult Participants w… Pending

2025-523525-17-00 Unresectable Locally Advanced or Metastatic Hepatocellu 9
A Study to Learn about the Study Medicine called PF-08634404 in Combination With Different Anticancer Agents in Advanced Cancers Pending

2025-523526-40-00 Advanced Solid Tumors 9
A phase II efficacy and safety study of cell-free circulating tumor DNA-guided commencement of second-line treatment in patients with DLBCL/… Pending

2024-518275-64-00 Diffuse large B-cell lymphomas (DLBCL, Diffuse large B- 4
Personnalized immunotherapy in patients with stage III non-small cell lung cancer Pending

2025-522801-39-00 Stage III Non Small Cell Lung Cancer 4
Pharmacokinetic Profiles of Subcutaneous vs. Intravenous Midazolam in Terminally Ill Patients in Palliative Care (PK-MID-PAL-study) Pending

2025-521082-26-00 Terminal illness requiring palliative care, with indica 4
Rollover study for participants who are currently being treated with and are continuing to benefit from opnurasib as a single agent or in co… Pending

2025-523537-26-00 Locally advanced or metastatic KRAS G12C-mutated non-sm 9
An open label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover bioequivalence study comparing Trametin… Pending

2025-524267-20-00 Adjuvant treatment of BRAF V600E or V600K mutation-posi 2
A study to investigate dabogratinib (TYRA-300) in participants with Low Grade Upper Tract Urothelial Carcinoma Pending

2025-523539-20-00 Low Grade Upper Tract Urothelial Carcinoma 4
Safety and Tolerability of REGN17235 in Adult Participants with Clonal Cytopenia of Undetermined Significance and Low-Risk Myelodysplastic S… Pending

2026-525464-18-00 Clonal Cytopenia of Undetermined Significance with SF3B 1
A Phase 2, single arm Multicenter, Study testing Mezigdomide, Carfilzomib, and Dexamethasone (480Kd) in Participants with Relapsed or Refrac… Pending

2025-521090-14-00 Patients with relapsed/refractory symptomatic multiple 4
A Phase I study to evaluate the safety and efficacy of L19IL2 in combination with ruxolitinib in patients with advanced solid tumors. Pending

2025-522243-17-00 Advanced solid tumors, specifically: • metastatic clea 3
A Study to Test How Well ZL-1310 may Work Compared to Therapies Selected by the Investigator in Treating Patients with Relapsed Small Cell L… Pending

2025-522818-23-00 Small Cell Lung Cancer (SCLC) 5
[18F]-olaparib PET; Molecular imaging of DNA damage response by [18F]-olaparib PET Pending

2024-511962-34-00 Head and neck squamous cell carcinoma (HNSCC) 7