Musculoskeletal Diseases

438 trials 179 recruiting

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Phase 2 Study of EDG-5506 in Becker Muscular Dystrophy Ended

2022-500090-13-00 Becker Muscular Dystrophy (BMD) 4 2022-12-29
A Study to Evaluate the Pharmacodynamics, Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7204239 in Participants with Facioscapul… Ended

2022-503117-36-00 Facioscapulohumeral muscular dystrophy (FSHD) 4 2022-12-01
Intervertebral Disc Regeneration by Autologous Stem Cell Transplantation Ended

2024-514475-17-00 degenerative disc disease 9 2022-11-15
A randomized, two-armed, single-blind, parallel, active controlled, and non-inferiority clinical trial to Compare Efficacy and Safety of ant… Ended

2024-515557-22-00 Juvenile Idiopathic Arthritis 6 2022-10-01
A Study to Evaluate Higher Dose (HD) Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy Previously Treated With Risdiplam (AS… Ended

2023-505639-11-00 Spinal Muscular Atrophy 5 2022-09-14
ATA-100 gene therapy trial in patients with limb-girdle muscular dystrophy Ended

2023-506677-36-00 FKRP-related limb-girdle muscular dystrophy (LGMD R9) 7 2022-07-18
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients with Multiple Sclerosis Ended

2023-505974-14-00 Multiple Sclerosis (MS) 5 2022-06-23
Efficacy, tolerability and preferences of per oral or subcutaneous methotrexate in patients with early rheumatoid arthritis – a randomised r… Ended

2024-512453-25-00 Rheumatoid arthritis 6 2022-04-28
New Clinical End-points in patients with primary Sjögren’s Syndrome: an Interventional Trial based on stratifYing patients Ended

2023-510054-16-00 Primary Sjogren's syndrome 4 2022-04-26
NOR-CACTUS Ended

2024-511223-34-00 Carpal Tunnel Syndrome 6 2022-04-08
Efficacy and safety of Frexalimab (SAR441344) in the treatment of Systemic Lupus Erythematosus Ended

2023-508654-26-00 Systemic lupus erythematosus 4 2022-03-15
A research study to compare different doses of a new investigational medicinal product for treatment of certain patients with Duchenne muscu… Ended

2024-511492-15-00 Duchenne Muscular Dystrophy 5 2021-12-09
Zoledronate Early to Hip Fractures Patients – safe and effective? A Randomized controlled double-blinded treatment strategy trial on Zoledro… Ended

2023-510198-32-00 Hip fracture 6 2021-12-01
Trial of different schemes of PM14 alone and in combination with radiotherapy in soft tissue sarcomas and other solid tumors Ended

2024-519893-38-00 Soft tissue sarcomas and other solid tumors 9 2021-11-23
Extension Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy Who Previously Participated in a Study With Nusinersen … Ended

2023-505637-27-00 Spinal Muscular Atrophy 5 2021-07-12
Phase III, multicentre, randomized, open clinical trial comparing treatment with allogenic mesenchymal cells against autologous mesenchymal … Ended

2024-514545-11-00 Knee osteoarthritis 5 2021-05-26
SPondyloArthritis: inducing drug-free Remission by early TNF-Alpha bloCkade Under guidance of Single cell RNA sequencing and epigenetic prof… Ended

2023-510085-27-00 Peripheral Spondyloarthritis 5 2020-08-21
A clinical trial to judge the safety, tolerability and effects on abnormal bone formation of reseach medication AZD 0530 (sarcatinib) in pat… Ended

2024-515186-33-00 Fibrodyplasia Ossificans Progressiva (FOP) 4 2020-01-08
A study to learn if combination pyrimidine nucleosides is safe, how well it works and how it moves through the bloodstream in participants w… Ended

2023-510427-29-00 Thymidine kinase 2 deficiency 4 2019-09-04
First-in-human study of AT132 in X-Linked Myotubular Myopathy (XLMTM) Patients Ended

2024-512637-32-00 X-linked Myotubular Myopathy (XLMTM) 10 2018-08-21
DupuytrEn Treatment EffeCtiveness Trial (DETECT) Ended

2024-515110-40-00 Dupuytren's contracture 5 2017-09-15
Filling bone erosions: a longitudinal multicentric HR-pQCT study of subcutaneous tocilizumab in rheumatoid arthritis Ended

2024-517686-17-01 rheumatoid arthritis 6 2016-06-30
RGX Ended

2024-514903-33-00 Osteoarthritis in the knee treated with cementless tota 4 2014-01-12
Non-inferiority study of a new therapeutic strategy for gout: immediate prescription of a hypouricemia treatment, febuxostat, compared to it… Halted

2024-515547-34-00 The gout 5 2025-08-12