Musculoskeletal Diseases

454 trials 185 recruiting

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Phase 3 Study of ALXN1850 in Pediatric Participants with HPP Previously Treated with Asfotase Alfa Revoked

2023-505674-15-00 Hypophosphatasia 5
Effect of Allogenic Ex-vivo Expanded Bone Marrow Derived Mesenchymal Stem Cells on Knee Osteoarthritis – A Randomized Controlled Trial Not authorised

2023-503974-19-00 Osteoarthritis in knee joint 10
Research into existing medicines to reduce aging, pain, and inflammation in osteoarthritis. Not authorised

2025-524885-12-00 Osteoarthritis 4
A 2-stage, Adaptive, Randomised, Double-blind, Placebo-controlled, Multicentre Study to Evaluate Dose and Treatment Effect of Pentosan Polys… Not authorised

2022-500228-31-00 Knee osteoarthritis pain 10
The effect of suprainguinal fascia iliaca compartment block Not authorised

2023-510388-37-00 Hip Pain 4
A phase I/IIa, prospective, mono-center, double-blinded, randomized, controlled study to assess the safety and efficacy of applying PLX-PAD … Not authorised

2023-504212-15-00 Osteoarthritis 9
Feasibility of short-term temporary discontinuation of serotonin reuptake inhibitors in patients planned for hip or knee arthroplasty Not authorised

2023-509988-24-00 Hip and knee osteoarthritis 11
Efficacy of peri-operative dexamethasone administration in single bundle anterior cruciate ligament reconstruction: a prospective randomized… Not authorised

2024-511559-17-00 Adult patients with indication of arthroscopic anterior 6
Comparison of treatment efficacy in the patients with Systemic sclerOsis: dapagliFlozin vs. Tocilizumab – a randomized head to head study Not authorised

2025-523714-92-00 Systemic Sclerosis 4
Topical Clobetasol Propionate for Inflammatory Hand osteoarthritis: A randomized trial versus placebo.(PROCLAME) Not authorised

2025-520678-20-00 Adult patients with symptomatic and inflammatory Hand o 5
Searching for the right dose of perineural dexmedetomidine for a interscalene plexus block. Not authorised

2023-506062-31-00 Patients scheduled for shoulder operations 11
Allogenic mesenchymal stem cell intraarticular injection for knee osteoarthritis therapy, an RCT explorative mode-of-action study Not authorised

2023-506088-33-00 knee osteoarthritis 9
Osteoporotic Fracture and Lidocaine plaster 5% for Neuropathic Pain preventioN (FLYNN) Pending

2025-524889-25-00 Osteoporotic Fracture 4
A Phase 3, Long-Term Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of Zasocitinib in Subjects with Active Pso… Pending

2025-522586-30-00 Psoriatic Arthritis 5
ATRIO Study: Effect of Romosozumab vs. Denosumab on Coronary Atherosclerotic Damage in Postmenopausal Osteoporosis: A Phase IV, Low-Risk Int… Pending

2025-522592-29-00 Coronary atherosclerotic status in women with postmenop 6
The usage of unenriched emulsified fat transplant in temporomandibular joint degenerative diseases Pending

2024-520244-41-00 Temporomandibular joint osteoarthritis, Wilkes classifi 4
Self-Assessment Method for Statin side-effects Or Nocebo 2 Pending

2025-524955-30-01 Cardiovascular diseases 11
SARA-31: A phase 3 trial to evaluate the efficacy and safety of BIO-101 in elderly patients suffering from severe SARcopeniA: an interventio… Pending

2022-502417-28-01 Sarcopenia 5
Sarilumab efficacy and safety in adults with early polymyalgia rheumatica Pending

2024-511296-15-00 Musculoskeletal diseases 5
A multicenter, randomized, open-label, blinded-assessor, phase 4 study in patients with early rheumatoid arthritis to compare active convent… Pending

2024-516723-14-00 Rheumatoid Arthritis 6
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants with Late-Onset Pompe Disease. Pending

2025-524082-25-00 Late-Onset Pompe Disease 7
Comparing surgical intervention versus infiltration of cytokine autologous rich serum (proteins derived from the patient's own blood) for th… Pending

2024-515941-40-00 Epicondylitis 6
ESTIS trial: Early Stop of targeted Treatment in children with Systemic JIA. Pending

2024-518684-35-00 autoimmune disorders, joint disorders synonym: Still's 6
Vaccination against respiratory syncytial virus in patients with inflammatory rheumatic diseases. The impact of anti-rheumatic treatments on… Pending

2024-518191-31-00 Inflammatory rheumatic disease 6