Musculoskeletal Diseases

438 trials 179 recruiting

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A Phase 3 Global Study to Evaluate AOC 1001 for the Treatment of Myotonic Dystrophy Type 1 Ended

2024-511378-60-00 Myotonic Dystrophy Type 1 5 2024-12-11
An open-label study to collect safety and effectiveness information on long-term treatment with vamorolone in boys with Duchenne Muscular Dy… Ended

2024-512828-12-00 Duchenne Muscular Dystrophy 6 2024-12-05
A multi-center, open-label extension study of subcutaneous secukinumab to evaluate the long-term safety and tolerability in polymyalgia rheu… Ended

2023-508077-85-00 Polymyalgia Rheumatica 5 2024-11-19
ALS phase II study of NX210c (SEALS) Ended

2023-508895-13-00 Amyotrophic Lateral Sclerosis (ALS) 4 2024-10-25
Intravenous immunoglobulin and prednisone vs. prednisone in newly diagnosed myositis: a double blind randomized clinical trial Ended

2024-516057-42-00 Idiopathic inflammatory myopathy 4 2024-10-10
A study to check the effect of satralizumab in children and adolescents living with Duchenne muscular dystrophy, to check if it is safe and … Ended

2024-512383-65-00 Duchenne Muscular Dystrophy (DMD) 4 2024-09-26
A Study on Diclofenac vs. Placebo for Knee Osteoarthritis Ended

2024-510757-95-01 Knee osteoarthritis 6 2024-08-01
COACH: A Phase 2, Open-Label, Single-Arm, 156-week Trial to Investigate the Efficacy, Safety and Tolerability of Combined Once Weekly Navepe… Ended

2023-508341-40-00 Children with Achondroplasia 4 2024-07-26
Phase IIa Proof-of-Concept Study to Investigate the Efficacy, Safety, and Tolerability of FBL-MTX in Patients with Rheumatoid Arthritis Ended

2023-510258-17-00 Rheumatoid arthritis (RA) 4 2024-07-24
Cell-mediated skipping of exon 51 for the genetic correction of dystrophin, based upon a single injection of autologous mesoangioblasts (MAB… Ended

2024-514860-14-00 Duchenne Muscular Dystrophy 7 2024-06-27
Metformin treatment of patients with hand osteoarthritis: A randomised, placebo-controlled trial Ended

2023-509181-38-00 Osteoarthritis 5 2024-05-03
KetCRPS-2 Ended

2024-511877-31-00 Complex regional pain syndrome 6 2024-04-22
A Phase 1/2, Open-Label, Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Intrav… Ended

2023-506737-30-00 Duchenne Muscular Dystrophy 7 2024-03-08
Allogenic mesenchymal stem cell intraarticular injection for knee osteoarthritis therapy, an RCT explorative mode-of-action study Ended

2023-506088-33-01 knee osteoarthritis 9 2024-03-07
Effects of BBP-418 (ribitol) in Patients with LGMD2I Ended

2023-503379-33-01 Limb Girdle Muscular Dystrophy 2I/R9 5 2024-02-12
The MERINO trial Ended

2023-510523-30-00 Erosive hand osteoarthritis 6 2024-02-09
A Phase 3, Open-label, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of Romosozumab Compared with Bisphosphonates in Chi… Ended

2023-503294-37-00 Osteogenesis Imperfecta 5 2023-11-20
Inhibition of JAK enzymes in early stage joint inflammation Ended

2024-514026-23-00 preclinical phase of rheumatoid arthritis 4 2023-09-06
A study to test product setrusumab in subjects with brittle bone syndrome. Ended

2024-510919-29-00 Osteogenesis imperfecta (OI) 10 2023-05-08
A Study to Assess Safety, Tolerability and Efficacy of Garetosmab versus Placebo Administered Intravenously (IV) in Adult Participants With … Ended

2023-508350-26-00 Fibrodysplasia Ossificans Progressiva 5 2023-03-02
A study to investigate the efficacy and safety of efgartigimod PH20 SC in adult participants with active idiopathic inflammatory myopathy Ended

2024-512785-33-00 Active Idiopathic Inflammatory Myopathy (IIM) 10 2023-03-01
REDUCE PMR: Rituximab Effect on Decreasing glUcoCorticoid Exposition in relapsing PolyMyalgia Rheumatica Ended

2024-513545-37-00 Polymyalgia rheumatica 6 2023-02-09
A study to test Taldefgropeb Alfa in patients with Spinal Muscular Atrophy. Ended

2024-511852-42-00 Spinal Muscular Atrophy 5 2023-01-19
Study of DYNE-251 in Participants with Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping Ended

2023-510351-31-00 Duchenne muscular dystrophy 7 2023-01-06