Mental Disorders

286 trials 120 recruiting

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Women victims of violences : PTSD treatment by traumatic memory reactivation under the influence of propranolol (VIOFEM) Pending

2025-523107-30-01 Post-traumatic stress disorder (PTSD) 5
Ketamine maintenance treatment for depression: A multicenter open-label randomized controlled trial (PreKET) Pending

2025-521330-29-00 Major Depression Disorder (MDD) 4
Early mental response to hormonal treatment in transgender men - The EMRE Study Pending

2024-517052-35-00 Transsexual 6
OSU6162 in Bipolar Depression: An Open-label, Flexible Dose Study (OBID) Pending

2024-517560-30-00 Bipolar depression 4
AugmENtation witH cAnnabidiol iN first episode psyChosis: a doublE blind randomised controlled trial (STEP-ENHANCE Trial) Pending

2025-521929-32-01 First Episode Psychosis (FEP) 5
EFFECTIVENESS OF SUPPLEMENTATION WITH VITAMIN D IN PATIENTS WITH DEPRESSIVE DISORDER OR BIPOLAR DISORDER: A RANDOMIZED CONTROLLED CLINICAL T… Pending

2025-520778-20-00 Depressive disorder 11
Oxytocin for drug relapse prevention Pending

2023-504518-31-01 substance use disorder 4
Study evaluating the efficacy and safety of daridorexant in patients with major depressive disorder and insomnia. Pending

2025-524794-16-00 Patients with major depressive episode and moderate to 6
Electrophysiological analysis of Gamma-Hydroxybutyrate-induced sleep in intensive care patients: A Pilot Double-Blind Randomized Controlled … Pending

2025-521967-11-00 The study population includes adult ICU patients with a 4
A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression) - X-CE… Recruiting

2025-522775-29-00 Depressive episodes associated with Bipolar disorder I 5 2026-06-05
An Open-label Study of Azetukalner in Major Depressive Disorder Recruiting

2025-523618-10-00 Major Depressive Disorder 5 2026-06-04
Open-label Extension of KarXT + KarX-EC for Agitation in Alzheimer’s Disease Recruiting

2024-519994-20-00 Agitation Associated with Alzheimer’s Disease 5 2026-06-01
Efficacy of EMONO as an add-on therapy to conventional antidepressants for the treatment of depressive symptoms in nursing-home residents wi… Recruiting

2023-504691-18-00 psychiatry 4 2026-05-01
A study for adolescents who are depressed and thinking of suicide Recruiting

2024-518615-19-00 Major Depressive Disorder 5 2026-04-22
A Phase 3 Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Bipol… Recruiting

2025-521845-26-00 BP-I mania or mania with mixed features 5 2026-03-02
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder Recruiting

2025-523202-32-00 Major Depressive Disorder 5 2026-02-26
Long-Term Safety and Tolerability of NBI-1117568 in Adults with Schizophrenia Recruiting

2025-521216-19-00 Schizophrenia 5 2025-12-10
Long-term study to assess the safety and tolerability of adjunctive NBI-1065845 in adults with Major Depressive Disorder (MDD) Recruiting

2024-519423-24-00 Major Depressive Disorder 5 2025-10-07
A Phase 3 Open-label Extension Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder Recruiting

2024-520259-26-00 Mania or Mania with Mixed Features in Bipolar-I Disorde 5 2025-09-25
A Phase 3 Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder Recruiting

2024-520195-94-00 BP-I mania or mania with mixed features 5 2025-09-25
A Randomized, Parallel-Group, Double-Blind, Placebo-Controlled, Monotherapy Study of the Efficacy, Safety, and Tolerability of SPT-300 in Ad… Recruiting

2025-521240-37-00 Major Depressive Disorder (MDD), with or without Anxiou 4 2025-09-11
A randomised, controlled trial to investigate the effect of a six-week intensified pharmacological treatment for bipolar depression compared… Recruiting

2023-506605-19-00 Bipolar depression 5 2025-02-11
Sodium-oxybate as a potential new treatment for catatonia in patients with depression, bipolar disorder or a psychotic disorder, a randomize… Recruiting

2024-517805-10-01 Catatonia 5 2024-11-12
A randomised, controlled trial to investigate the effect of a six-week intensified pharmacological treatment for schizophrenia compared to t… Recruiting

2023-506602-39-00 schizophrenia, schizoaffective disorder, schizophrenifo 6 2024-08-01