Mental Disorders

286 trials 120 recruiting

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Microdosing for ADHD and emotion regulation Not authorised

2025-520906-36-00 Attention Deficit Hyperactivity Disorder (ADHD) 4
Psilocybin's effects on anhedonia Not authorised

2023-509009-59-00 Major Depressive Disorder 3
The Acute and Long-term Impact of Support and Music in Psilocybin Therapy for Depression: The Psilocybin Setting Trial (PSISET) Not authorised

2025-522961-31-00 Depression 4
An open label safety and efficacy study of allogenic adipose tissue-derived mesenchymal stromal cells on autism and gastrointestinal symptom… Not authorised

2025-523699-21-00 Gastrointestinal symptoms 3
The additive effect of ketamine in combination with electroconvulsive stimulation (ECS) in major depressive disorder (MDD): a translational … Not authorised

2024-512559-20-00 Major Depressive Disorder (MDD) 5
A randomised, controlled trial to investigate the effect of a four/six week intensified pharmacological treatment for schizophrenia, major d… Not authorised

2022-502185-24-00 Schizophrenia, schizoaffective disorder, schizophrenifo 5
A one-year study to assess if Xanomeline/Trospium (XT) can improve cognitive function in adults living with schizophrenia. Not authorised

2025-523060-20-00 Schizophrenia 5
Pharmacological treatment of compulsive sexual behaviour disorder Not authorised

2024-514490-22-00 Compulsive Sexual Behaviour Disorder 5
Can the Gut Help Fight Addiction? A Clinical Study on Rifaximin and the Microbiota–Brain Connection Not authorised

2025-524778-41-00 substance use disorder 4
First administration in healthy volunteers of a single and increasing dose of a new molecule for the treatment of brain diseases Not authorised

2023-505030-99-00 Post-Traumatic Stress Disorder (PTSD) 1
Prevention of Sexual Offending with Cognitive Behavioral Therapy Alone Versus Therapy Combined with Testosterone Suppression – the PREVENT-M… Pending

2024-518120-68-01 Paraphilic disorder, Compulsive sexual behavior disorde 4
Psilocybin-Assisted Psychotherapy for Posttraumatic Stress Disorder in Military Veterans: A Pilot Feasibility Study Pending

2025-521488-11-00 Posttraumatic stress disorder 4
Phase 3 Evaluation of KarXT and KarXT+KarX-EC in Schizophrenia and Autism-Related Irritability in Youth, respectively. Pending

2025-524062-16-00 Schizophrenia and Autism Spectrum Disorder (ASD) 5
SHIELD – Swift Hydrocortisone Intervention after trauma exposure Pending

2025-523350-13-02 Posttraumatic Stress Disorder (PTSD) 4
Psilocybin in treatment-resistant depression Pending

2024-518654-16-01 Treatment-resistant depression 4
A Randomized, Delayed-Treatment Controlled, Phase 2 Pilot Study of Manualized MDMA-Assisted Therapy for Young Adults with Chronic Treatment-… Pending

2024-520319-42-01 Major Depressive Disorder 4
An open label, balanced, randomized, two-treatment, two-period, two-sequence, single dose crossover, bioavailability study comparing Bupropi… Pending

2025-523410-84-00 Seasonal affective disorder 2
An open label, balanced, randomized, three treatment, three period, three sequence, single dose, crossover study to assess the effect of foo… Pending

2025-523411-11-00 Seasonal affective disorder 3
Randomised open-label pilot Study on Thiamine supplementation to REduce braiN injury associated with chronic Alcohol use in outpatients with… Pending

2025-524148-36-00 Alcoholism 4
Clinical trial to determine the efficacy and safety of AP707 in the treatment of Borderline Personality Disorder Pending

2024-510873-11-00 Borderline personality disorder 4
Unraveling the aesthetic mind in anhedonia, insights from pharmacological imaging of the human brain: A single-blind, randomized, placebo-co… Pending

2024-517252-35-00 Depression 3
Skin irritation and sensitization trial Pending

2026-525269-34-00 The intended indication is for the treatment of major d 3
EPABID: Efficacy of Pipamperone and Aripiprazole on Behaviors that challenge in Intellectual Disabilities Pending

2024-519833-51-00 Behaviors that challenge 6
Long-term outcomes and safety of repeated rituximab treatment in psychotic disorders – RITS-LONG Pending

2026-525324-26-00 Schizophrenia spectrum disorder (SSD) 4