Hemic and Lymphatic Diseases

593 trials 238 recruiting

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Phase II multicenter single arm study to evaluate the efficacy and safety of ibrutinib in combination to rituximab-CHOP followed by ibrutini… Ended

2024-511641-18-00 Diffuse Large B-cell Lymphoma ABC 4 2019-08-01
A phase 3B, open-label, single-arm, rollover study to evaluate long-term safety of Luspatercept in subjects who have participated in other L… Ended

2022-502498-40-00 myelodysplastic syndrome (MDS); beta (β)-thalassemia (T 5 2019-07-26
HEAT-AML (Hydroxyurea-Enhanced Ara-C Treatment of Adult Acute Myeloid Leukaemia): A clinical study to assess whether addition of hydroxyurea… Ended

2023-509019-97-00 Newly diagnosed acute myeloid leukaemia (AML) in patien 9 2019-07-15
APIS Apixaban for Intrahepatic Non Cirrhotic Portal Hypertension Ended

2024-514348-95-00 Intrahepatic non-cirrhotic portal hypertension 5 2019-06-24
OPEN LABEL PHASE 2 STUDY ON THE EFFICACY AND TOLERANCE OF A COMBINATION OF PONATINIB AND 5-AZACITIDINE IN CHRONIC MYELOGENOUS LEUKAEMIA IN A… Ended

2024-516048-24-00 CHRONIC MYELOGENOUS LEUKAEMIA IN ACCELERATED PHASE OR I 4 2019-06-19
IMPACT OF INTRAVENOUS IRON TREATMENT OF PREOPERATIVE ANEMIA IN PATIENTS WITH LOWER EXTREMITY PERIPHERAL ARTERY DISEASE (IRONPAD) Ended

2024-514593-50-00 Anemia in patients with chronic ischemia of the lower l 6 2019-06-06
Study of the efficacy of treatment with AG-120 in patients with Myelodysplastic Syndrome and mutation IDH1 Ended

2024-515352-20-00 myelodysplastic syndrome with IDH1 mutated 4 2019-03-20
A Study of Avapritinib in Patients with Indolent and Systemic Mastocytosis Ended

2024-512585-34-00 Indolent Systemic Mastocytosis (ISM) 4 2019-02-27
study of the efficacy of treatment with AG-221 in patients with myelodysplastic syndrome and mutation IDH2 Ended

2024-513858-29-01 myelodysplastic syndrome with IDH2 mutated 4 2019-02-06
A Phase 3 study to see the benefit and safety of Luspatercept in comparison with Epoetin Alfa to treat anaemia due to very low, low or inter… Ended

2022-501485-22-00 Myelodysplastic syndrome (MDS) 5 2018-12-18
Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood Ended

2023-510009-16-00 Acute Myeloid Leukemia 9 2018-12-04
An Efficacy Study Comparing Ponatinib Versus Imatinib, Administered in Combination with Reduced-Intensity Chemotherapy, in Participants with… Ended

2023-508463-71-00 Newly Diagnosed Philadelphia Chromosome-Positive Acute 5 2018-11-30
Study to test the safety and how well patients with severe hemophilia A respond to treatment with BAY 2599023 (DTX 201), a drug therapy that… Ended

2023-505827-29-00 Hemophilia A 7 2018-10-30
Study to determine safety, efficacy and tolerability of Venetoclax in combination with Fludarabine, Citarabine and Idarubicin to achieve "th… Ended

2023-510517-26-00 Acute Myeloid Leukemia 9 2018-10-26
A randomized phase III trial assessing the benefit of the addition of isatuximab to lenalidomide / bortezomib / dexamethasone (RVd) inductio… Ended

2024-513464-26-00 Multiple Myeloma 5 2018-10-18
A global study to assess the effects of Osimertinib following chemoradiation in patients with Stage III unresectable non-small cell lung can… Ended

2022-500860-36-00 Histologically documented non-small cell lung cancer of 5 2018-09-19
AIEOP-BFM ALL 2017 - International collaborative treatment protocol for children and adolescents with acute lymphoblastic leukemia Ended

2023-509856-32-00 acute lymphoblastic leukemia in children and adolescent 5 2018-07-15
MB-CART19.1 r/r CD19+ BCM Ended

2024-513334-38-00 Refractory/relapsed B-NHL 1 2018-05-15
Obinutuzumab in marginal zone lymphoma - A MULTICENTER OPEN LABEL SINGLE-ARM PHASE II STUDY (OLYMP-1) Ended

2024-517476-38-00 Marginal Zone Lymphoma 4 2018-05-14
Transplant BRaVE NHL: Phase I-II study combining Brentuximab Vedotin with second line salvage chemotherapy (R-DHAP) in CD30 positive diffuse… Ended

2023-510556-22-00 non-Hodgkin lymphoma (NHL) 4 2018-03-05
A Phase 3 study to test the AG-120 in combination with Azacitidine in comparison with the use of Azacitidine alone in patients ≥ 18 Years of… Ended

2024-514309-73-00 Previously Untreated Acute Myeloid Leukemia with an IDH 5 2018-02-06
ENRICH - Randomised, open label study of Rituximab/Ibrutinib vs Rituximab/Chemotherapy in older patients with untreated mantle cell lymphoma Ended

2024-514275-18-00 Mantle Cell Lymphoma (MCL) 10 2017-12-06
An Open label Study of Teclistamab in Subjects with Relapsed and Refractory Multiple Myeloma Ended

2023-503438-40-00 Relapsed/Refractory Multiple Myeloma 7 2017-10-05
A Clinical Phase II, multicenter, Open-label study evaluating iNduction, consolidation and maintenance treatment with Isatuximab (SAR650984)… Ended

2024-511791-32-00 Multiple Myeloma 4 2017-08-15