Hemic and Lymphatic Diseases

593 trials 238 recruiting

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Study aimed at evaluating the efficacy of a combination treatment (decitabine and venetoclax) in patients with Acute Myeliode Leukemia who a… Ended

2023-510241-16-00 Acute Myeloid Leukemia secondary to myeloproliferative 4 2021-12-03
Shortened vs standard chemotherapy combined with immunotherapy for the initial treatment of patients with high tumor burden Follicular Lymph… Ended

2024-511636-27-00 Follicular Lymphoma 5 2021-12-01
An open label, multicenter, phase I/II study of belantamab mafodotin in combination with Kd for the treatment of relapsed myeloma patients, … Ended

2024-517006-28-00 Multiple myeloma 9 2021-11-23
FILOCLL14 - STAIR : "Open-label, phase 2 study investigating the STop and restart Acalabrutinib In fRrail patients with previously untreated… Ended

2024-513936-80-00 elderly patients (> 70 years) with CLL or SLL 4 2021-11-12
A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC (Tec-Dara) versus Daratumumab SC, Pomalidomide, and Dexa… Ended

2023-503441-55-00 Relapsed/Refractory Multiple Myeloma 4 2021-10-14
A study to determine the safe dose of iberdomide (CC-220) in combination with R-CHOP21 and CC-98282 in combination with R-CHOP21 in subjects… Ended

2023-506094-35-00 Newly diagnosed aggressive B-cell lymphoma (a-BCL) 3 2021-09-17
The study aims to verify the greater efficacy of the treatment of Acute Lymphoblastic Leukemia Ph + through the combination of Ponatinib and… Ended

2023-508968-30-00 Adult Philadelphia Chromosome-Positive Acute Lymphoblas 5 2021-09-08
Long term access to berotralstat for HAE subjects from previous clinical trials. Ended

2024-511285-37-00 Hereditary Angioedema 11 2021-08-31
A Study Evaluating the Efficacy and Safety of Crovalimab in Adult and Adolescent Patients with atypical Hemolytic Uremic Syndrome (aHUS) Ended

2023-505089-27-00 Atypical Hemolytic Uremic Syndrome (aHUS) 5 2021-07-01
Optimizing MATRix, a combination of Methotrexate, Ara-C, Thiotepa and Rituximab given as an induction therapy, de-escalated in duration and … Ended

2024-514473-21-00 Primary diffuse large B-cell lymphoma (DLBCL) of the ce 5 2021-06-21
Study of BGB-11417 in Patients with Mature B Cell Malignancies Ended

2024-515592-35-00 Mature B Cell Malignancies 1 2021-06-14
Protocol Title: Phase 3, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of PF-07055480 (Recombinant AAV2/6 Human Factor VI… Ended

2024-512075-12-00 hemophilia A 5 2021-06-14
Rollover Study for Patients with Sickle Cell Disease who have Completed a prior Novartis-Sponsored Crizanlizumab Study Ended

2024-510734-41-00 Sickle cell disease 6 2021-06-10
Daratumumab for first line treatment of transplant-ineligible myeloma patients followed by daratumumab re-treatment at first relapse (GMMG-D… Ended

2024-517761-17-00 Multiple Myeloma 4 2021-05-31
The aim of the study is to evaluate the efficacy of Ponatinib, either alone or in combination with chemotherapy, in inducing remission in pa… Ended

2024-516868-28-00 Ph+ Acute Lymphoblastic Leukemia 4 2021-05-04
A Study to Evaluate the Efficacy and Safety of Crovalimab versus Eculizumab in Adult and Adolescent Patients with Paroxysmal Nocturnal Hemog… Ended

2023-506498-36-00 Paroxysmal Nocturnal Hemoglobinuria (PNH) 5 2021-04-08
A Study of TL-895 in Myelofibrosis, Indolent Systemic Mastocytosis, Monoclonal Mast Cell Activation Syndrome, or Non-Monoclonal Mast Cell Ac… Ended

2024-514467-26-00 Indolent Systemic Mastocytosis 4 2021-04-07
Prephase treatment with prednisone +/- Vitamin D supplementation followed by immunochemotherapy in Elderly patients with Diffuse Large B-Cel… Ended

2024-511637-35-00 Elderly patients with Diffuse Large B-Cell Lymphoma (DL 5 2021-03-23
A Study Evaluating The Safety, Pharmacokinetics, and Efficacy Of Crovalimab Versus Eculizumab In Participants With Paroxysmal Nocturnal Hemo… Ended

2023-506526-37-00 Paroxysmal Nocturnal Hemoglobinuria (PNH) 5 2021-03-17
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12… Ended

2023-505964-13-00 Hemophilia A 5 2021-03-09
A Multi-arm Phase 1b Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma Ended

2023-503440-14-00 Relapsed/Refractory Multiple Myeloma 3 2021-03-08
A Study of Osimertinib with or without Chemotherapy versus Chemotherapy alone as neoadjuvant therapy for Patients with Epidermal Growth Fact… Ended

2022-502606-33-00 Patients with histologically or cytologically documente 5 2021-02-26
A study to evaluate the benefit and safety of Luspatercept (ACE-536) in adults with myeloproliferative neoplasm-associated myelofibrosis on … Ended

2023-507890-17-00 Anemia associated with myeloproliferative neoplasm (MPN 5 2021-02-22
CD19-CAR_Lenti in pediatric patients affected by relapsed/refractory B-ALL or aggressive B-NHL Ended

2024-519174-39-00 Relapsed/refractory CD19+ Acute Lymphoblastic Leukemia 7 2021-02-15