Digestive System Diseases

646 trials 307 recruiting

Filter these 646 trials by phase, country and sponsor.

Open in Search →

Utility of the use of N-acetylcisteine associated with conventional treatment in patients with severe acute alcoholic hepatitis (Maddrey>=32… Pending

2023-510163-35-00 Acute Alcoholic hepatitis 5
Optimizing the antibiotic treatment of uncomplicated acute appendicitis - APPAC II Pending

2024-518984-36-00 Uncomplicated acute appendicitis 6
Efficacy and safety of a novel dual pH-dependent delayed-release ColeseveLam for the trEatment of bile Acid diarrhoea: a Randomized, double-… Pending

2025-523868-20-00 Bile acid diarrhoea 4
Dual-agent fluorescence-guided surgery for colorectal liver metastases Pending

2025-524755-31-00 Colorectal liver metastases 10
Treatment of Chronic Anal Fissure with Botulinum Toxin A Pending

2025-520748-13-01 Chronic anal fissure 6
A phase 1, open-label, dose-escalation and dose-expansion study evaluating the safety, feasability and efficacy of ODI-2001 vaccine, a perso… Pending

2025-523172-23-00 Metastatic or locally advanced pancreatic cancer 1
The value of post-operative antibiotic therapy after laparoscopic appendectomy for complicated acute appendicitis (other than for generalize… Pending

2024-515834-34-00 complicated acute appendicitis 5
IMMUNOPEC: Combination of neo-adjuvant Checkpoint Inhibition and Dendritic Cell Therapy (MesoPher) with Cytoreductive Surgery and Hypertherm… Pending

2024-519626-21-00 Peritoneal Mesothelioma 4
Antibiotic therapy vs. placebo in the treatment of acute uncomplicated appendicitis: a prospective randomized double-blind placebo-controlle… Pending

2025-520761-44-00 Uncomplicated acute appendicitis 6
Applying Mysimba in patients with weight regain after bariatric surgery Pending

2024-516645-39-01 Obesity 11
Oral Fecal Microbiota Transplantation in Pediatric Ulcerative Colitis (UC) Pending

2024-518044-20-00 Ulcerative Colitis 4
FirST lines of biologics in pAtients with ulceRaTivE colitis: a Randomised controlled trial Pending

2024-514964-24-00 ulcerative colitis 5
A Randomized, Double-Blind, Placebo Controlled, Multi - Center, Phase 1b Study to Evaluate the Safety and Tolerability of LIV001 in Patients… Pending

2024-514520-16-00 mild-to-moderate active ulcerative colitis 3
Efficacy of amoxicillin/clavulanic acid after surgical drainage of perianal abscess in the prevention of the development of anal fistula. A … Pending

2024-520193-35-00 Patients who underwent surgery for their first episode 6
Shared decision-making in uncomplicated appendicitis: a pragmatic randomized trial comparing patient-driven choice (antibiotics only or appe… Pending

2025-520783-17-01 Adult patients diagnosed with uncomplicated acute appen 4
Normal saline versus lactated Ringer’s solution for fluid administration in acute pancreatitis, an open-label multicenter randomized control… Pending

2024-511229-79-00 Acute Pancreatitis 6
A Phase I trial to investigate the pharmacokinetics and ECG effects of single doses of linaprazan glurate administered as oral tablets to he… Pending

2024-516261-36-00 Erosive Gastroesophageal Reflux Disease (eGERD) 3
A clinical trial of MK-8690 in people with ulcerative colitis (MK-8690-002) Recruiting

2025-523479-49-00 Colitis ulcerative 4 2026-06-29
A study of LY4268989 in participants with Moderately to Severely Active Ulcerative Colitis (EMERALD-3) Recruiting

2025-524404-29-00 Ulcerative Colitis, Active Moderate 4 2026-06-24
Immunosuppressant Discontinuation in Elderly patients with ulcerative colitis And long-term remission Recruiting

2025-524675-23-00 Ulcerative Colitis 6 2026-06-24
Efficacy and safety of Ursodeoxycholic Acid as a new therapy for the treatment of hepatorenal polycystic diseases, genetic study and determi… Recruiting

2024-513644-28-00 Hepatorenal polycystic diseases 4 2026-06-18
Perioperative Therapy with Durvalumab Plus Tremelimumab for Patients with Resectable Hepatocellular Carcinoma (HCC) - A Phase II Trial (NEOT… Recruiting

2023-508863-59-01 Resectable Hepatocellular Carcinoma 4 2026-06-17
Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC) (RASolute 304) Recruiting

2025-523495-23-00 Resected Pancreatic Ductal Adenocarcinoma (PDAC) 5 2026-06-09
An Early-Stage Study in Multiple Clinics of how Afimkibart May Affect the Body’s Processing of Medicines that Rely on Cytochrome P450 Enzyme… Recruiting

2025-524060-38-00 Active Ulcerative Colitis (UC) 3 2026-05-28