Digestive System Diseases

646 trials 307 recruiting

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Multicenter Extension Study of Oral Ozanimod in patients with Moderately to Severely Active Crohn's Disease Ended

2024-511553-22-00 Moderately to Severely Active Crohn's Disease 5 2018-10-05
Multicenter Study of Oral Ozanimod as Maintenance Therapy in patients with Moderately to Severely Active Crohn's Disease Ended

2023-510426-33-00 Moderately to Severely Active Crohn's Disease 5 2018-09-27
FFCD 1605- OPTIPRIME: A phase II study evaluating FOLFOX + panitumumab according to a ‘stop-and-go’ strategy with a reintroduction loop afte… Ended

2024-518740-20-00 metastatic colorectal adenocarcinoma 4 2018-04-26
Treatment of refractory Crohn's disease lesions by local injection of mesenchymal stem cells Ended

2024-514033-37-00 Crohn's Disease 9 2018-03-01
An extension study to investigate how safe Vedolizumab is in child patients with Ulcerative Colitis or Crohn's Disease Ended

2023-507766-35-00 Ulcerative Colitis or Crohn's Disease 4 2018-01-09
Double-blind, randomized, placebo-controlled, phase III study comparing norursodeoxycholic acid capsules with placebo in the treatment of pr… Ended

2023-510200-42-00 primary sclerosing cholangitis (PSC) 5 2017-12-06
Ramucirumab plus Irinotecan / Leucovorin / 5-FU versus Ramucirumab plus Paclitaxel in patients with advanced or metastatic adenocarcinoma of… Ended

2024-512934-14-00 advanced or metastatic adenocarcinoma of the stomach or 5 2016-11-07
A Study to Evaluate the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of Upadacitinib (ABT-494) in Participants Wi… Ended

2024-510727-19-00 Crohn's Disease (CD) 4 2016-10-11
A Multi-Center, Open-Label Study of Adalimumab to Evaluate Long-Term Safety and Tolerability of Repeated Administration of Adalimumab in Ped… Ended

2023-504711-32-00 Ulcerative Colitis 5 2015-11-24
The purpose of this study is to determine whether long-term RPC1063 is safe and effective in the treatment of ulcerative colitis (UC) Ended

2024-514815-92-00 Ulcerative colitis 5 2015-07-16
GASTRICHIP TRIAL. D2 resection and HIPEC (Hyperthermic IntraPeritoneal Chemoperfusion) in locally advanced gastric carcinoma. Ended

2024-516358-23-00 Gastric adenocarcinoma 5 2013-06-24
ATTENUATION – A multicenter randomized phase II study of the efficacy and safety de-escalation versus standard adjuvant chemotherapy in pati… Ended

2023-509227-41-00 Low risk of disease recurrence, defined by the followin 4
Medical research to compare the effectiveness of infliximab injections alone or in combination with immunosuppressive drugs in the treatment… Ended

2024-517171-20-00 Crohn's disease 6
Effect of citalopram on chest pain in patients with achalasia. Ended

2024-517701-81-01 Achalasia 6
PRODIGE 111 – DOMZIGAST A randomized phase II study evaluating FOLFIRI vs FOLFIRI plus Domvanalimab (anti-TIGIT) and Zimberelimab (anti-PD1)… Ended

2024-519258-35-00 stomach cancer 4
A randomized, phase 3 multicenter clinical trial to confirm the clinical efficacy and evaluate the safety of linaprazan glurate compared to … Ended

2025-522750-39-00 Erosive esophagitis (EE) due to gastroesophageal reflux 5
Normal saline versus lactated Ringer’s solution for acute pancreatitis resuscitation, an open-label multicenter randomized controlled trial:… Ended

2023-509879-16-00 Acute pancreatitis 6
Evaluating the efficacy and safety of hyperbaric oxygen therapy as an adjuvant treatment compared to biologic therapy alone in moderate to s… Ended

2023-507450-32-00 Ulcerative colitis 5
PRODIGE 76-IMMUNOBILADJ: Capecitabine plus durvalumab or capecitabine alone as adjuvant therapy in patients with resected biliary tract carc… Ended

2023-503807-27-00 Biliary tract carcinoma 4
A Randomized, Double-blind, Placebo-controlled, Phase 2/3 Study to Assess the Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmaco… Ended

2023-503926-37-00 Biliary Atresia, Post-hepatoportoenterostomy 10
Open-label non-randomized multicentric phase 2 study evaluating the combination of bemarituzumab + FLOT chemotherapy in perioperative settin… Ended

2024-514078-29-00 gastric and gastro-oesophageal junction adenocarcinomas 4
Simvastatin in the Prevention of Recurrent Pancreatitis, a Triple Blind, Randomized Controlled Trial. Ended

2024-513188-17-03 Recurrent pancreatitis 6