Digestive System Diseases

647 trials 308 recruiting

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A double blinded, balanced, randomized, two-treatment, four-period, two-sequence, single-dose, crossover fully replicate bioequivalence stud… Pending

2025-522106-20-00 ulcerative colitis 2
Oral Antibiotic Outpatient Therapy vs. Placebo in the Treatment of Uncomplicated Acute Appendicitis Pending

2023-506213-21-00 Uncomplicated acute appendicitis 6
A clinical trial comparing how the body takes up budesonide from different forms of medicine when taken by mouth with or without food. Pending

2025-522686-29-00 Acute eosinophilic esophagitis 3
J6Z-MC-IIBD - A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn’s Disease J6Z-MC-CD01 - A Stud… Pending

2025-524112-11-00 J6Z-MC-IIBD - Colitis, Ulcerative Crohn Disease J6Z-M 4
A randomized, balanced, two-treatment, two-sequence, single oral dose, two stage crossover adaptative bioequivalence study of Rifaximin 200 … Pending

2025-525078-12-00 healthy subjects 2
Methotrexate in paediatric and adolescent Crohn’s disease: an observational study Pending

2025-524129-42-00 Crohn’s disease 6
ATLAS trial Pending

2024-517233-40-00 Perianal abscess 6
Comparison of azathioprine to methotrexate in combination therapy with adalimumab in Crohn’s Disease: an open-label randomized controlled tr… Pending

2024-514633-38-00 Crohn’s Disease 5
A study to evaluate the safety and tolerability of single ascending doses of AGMB-101 in healthy participants (Part A) and patients with liv… Pending

2024-515074-26-00 liver cirrhosis 1
Fecal microbiota transplantation in patients receiving infliximab and vedolizumab for ulcerative colitis: A randomized controlled trial Pending

2024-520373-12-00 Ulcerative Colitis, Crohn´s disease 6
A clinical study investigating modafinil for the treatment of severe fatigue in patients with inflammatory bowel disease (MODIFI-IBD trial) Pending

2026-525163-41-00 Inflammatory bowel disease 10
Efficacy of top-down therapy with mirikizumab versus standard of care with azathioprine in patients with newly diagnosed, moderate-to-sever… Pending

2026-525191-26-00 Crohn’s disease 6
Cholesterol lowering with atorvastatine for the prevention of gallstones following bariatric surgery: an investigator- blinded randomised co… Pending

2025-524191-38-00 Gallstones (chole(cysto)lithiasis) following bariatric 6
RESET C2 Pending

2026-525214-62-00 Localised dMMR Colon Cancer 4
A double blinded, balanced, randomized, two-treatment, four-period, two-sequence, single-dose, crossover fully replicate bioequivalence stud… Pending

2025-521598-16-00 ulcerative colitis 2
Ursodeoxycolic acid for the prevention of relapsing complications after gallstone acute pancreatitis, a double-blind multicenter randomized-… Pending

2024-518237-28-00 recurrence of acute biliary pancreatitis 6
Impact of early proactive therapeutic drug monitoring on the durability and efficacy of infliximab therapy in pediatric inflammatory bowel d… Pending

2024-517759-11-00 Inflammatory Bowel Disease 6
Efficacy of combined treatment by autologous cell therapy and percutaneous transluminal angioplasty (PTA) versus the treatment by isolated P… Pending

2024-512873-29-00 chronic limb-threatening ischemia 4
IMPACT OF ANTI-TNF, VEDOLIZUMAB AND TOFACITINIB ON AORTIC STIFFNESS, CAROTID INTIMA-MEDIA THICKNESS AND CARDIOVASCULAR RISK OF PATIENTS WIT… Pending

2024-517314-15-00 ulcerative colitis 11
Fibroblast markers to tackle fibrosis in immune-mediated inflammatory diseases Pending

2025-522834-30-01 Systemic sclerosis (SSc) 4
Clinical trial in people with celiac disease to analyze whether intestinal lactase activity is related to alterations in the intestinal barr… Pending

2026-525518-70-00 Patients with celiac disease 6
Debut of Ulcerative Colitis: selective Top-down strategy - the DUCT trial Pending

2024-519891-17-00 Ulcerative colitis 4
A Phase 1 Study of AIR-001 in Adults with AATD. Pending

2025-523558-14-00 Alpha-1 Antitrypsin Deficiency 1
A medical research to evaluate if MaaT013 is safe and helps children and adolescent with GI-aGvHD after failed two prior therapies. Pending

2025-524302-15-00 Gastrointestinal Acute Graft-versus-Host Disease (GI-aG 4