Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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A Phase 3 study of Tafasitamab plus Lenalidomide in addition to Rituximab, versus Lenalidomide plus Rituximab in patients With Relapsed/Refr… Ended

2023-504684-16-00 follicular lymphoma (FL) and marginal zone lymphoma (MZ 2021-06-05
Trastuzumab deruxtecan (T-DXd) with or without Pertuzumab versus Taxane, Trastuzumab and Pertuzumab as First-line Treatment in HER2-positive… Ended

2023-505249-24-00 HER2-positive metastatic breast cancer 2021-05-27
Phase III, multicentre, randomized, open clinical trial comparing treatment with allogenic mesenchymal cells against autologous mesenchymal … Ended

2024-514545-11-00 Knee osteoarthritis 2021-05-26
Comparing Paclitaxel-Carboplatin-Oregovomab versus Paclitaxel-Carboplatin-Placebo in Patients with Advanced Ovarian Cancer Ended

2024-519218-30-00 Advanced epithelial ovarian, fallopian tube or peritone 2021-05-26
A study to evaluate the safety and tolerability of seladelpar in subjects with primary biliary cholangitis Ended

2024-511753-22-00 Primary Biliary Cholangitis 2021-05-26
A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Atrasentan in Patients with IgA Nephropathy at Risk of Progressive Loss of … Ended

2024-513227-16-00 Immunoglobulin A Nephropathy (IgAN) 2021-05-19
An Open-label, Randomized Phase 3 Study of Immune and Targeted Combination Therapies, as First-line Treatment in Participants with Advanced … Ended

2022-502122-41-00 Clear cell renal cancer 2021-05-11
A Randomised, Double-Blind, Phase III Study of AZD9833 plus Palbociclib versus Anastrozole plus Palbociclib in Patients with ER-Positive HER… Ended

2023-503995-26-00 Estrogen Receptor-Positive, HER2-Negative Advanced Brea 2021-05-11
Once-daily inhaled molgramostim nebulizer solution in aPAP Ended

2024-511052-41-00 Autoimmune Pulmonary Alveolar Proteinosis 2021-05-10
DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer Ended

2023-509865-19-00 Advanced or Metastatic Non-small Cell Lung Cancer (NSCL 2021-04-30
Phase 3 Trial of Perioperative EV and Pembro vs. Chemo in Cis-E MIBC Ended

2023-505615-21-00 Muscle Invasive Bladder Cancer 2021-04-28
Non-inferiority study of ocrelizumab and rituximab in active multiple sclerosis Ended

2024-514287-84-00 Multiple sclerosis 2021-04-28
Trial comparing the efficacy and safety of tafasitamab plus lenalidomide in addition to standard therapy versus standard therapy in patients… Ended

2022-500237-92-00 Newly-diagnosed high-intermediate and high-risk diffuse 2021-04-23
A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (M… Ended

2023-507188-21-00 Muscle-Invasive Urothelial Carcinoma (MIBC) of the Blad 2021-04-20
Clinical trial comparing Trastuzumab Deruxtecan with Trastuzumab Emtansine in high-risk HER2-positive patients with residual breast cancer f… Ended

2023-507961-24-00 High-Risk HER2-Positive Breast Cancer 2021-04-19
Phase 3 Study of Belzutifan in Combination With Lenvatinib Versus Cabozantinib for Treatment of RCC Ended

2024-510620-39-00 Advanced RCC with clear cell component 2021-04-19
A Study to Evaluate Efficacy and Safety of Obinutuzumab in Patients with Primary Membranous Nephropathy Ended

2023-506525-11-00 Primary Membranous Nephropathy (pMN) 2021-04-19
A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive… Ended

2023-503568-18-00 Early human epidermal growth factor receptor 2 (HER2) p 2021-04-13
A study comparing current available therapies with imetelstat for the treatment of intermediate-2 or high-risk MF who are not responding to … Ended

2023-509120-17-00 Myelofibrosis 2021-04-12
Safety and Immunogenicity of Extended 2-dose Regimens of 9vHPV Vaccine Ended

2022-500256-37-00 Prevention of persistent anogenital HPV infection and d 2021-04-08
A Study to Evaluate the Efficacy and Safety of Crovalimab versus Eculizumab in Adult and Adolescent Patients with Paroxysmal Nocturnal Hemog… Ended

2023-506498-36-00 Paroxysmal Nocturnal Hemoglobinuria (PNH) 2021-04-08
Double blind, multicentric, randomized, placebo-controlled trial, evaluating the efficacy of 24-month of bezafibrate in primary sclerosing c… Ended

2024-511658-28-01 primary sclerosing cholangitis 2021-04-06
Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With locally advanced, Unresectable ESCC Ended

2023-506413-22-00 Locally Advanced Unresectable Esophageal Squamous Cell 2021-03-31
An Open-label study comparing 177Lu-PSMA-617 plus Standard of Care vs. Standard of Care in the Treatment of mHSPC Ended

2023-507970-42-00 PSMA-positive metastatic hormone-sensitive prostate can 2021-03-31