Therapeutic Confirmatory (Phase III)

3,299 trials 1,320 recruiting

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An Open-Label Extension to Study the Long-Term Effect of Dexpramipexole in Participants with Severe Eosinophilic Asthma (EXHALE-5) Under evaluation

2024-510810-33-00 Severe eosinophilic asthma 2024-10-14
Phase 3 Study of ALXN1850 in Pediatric Participants with HPP Previously Treated with Asfotase Alfa Revoked

2023-505674-15-00 Hypophosphatasia
Maintenance Therapy of the Effects of Donepezil-iGaLa Combined Therapy in Post-Stroke Chronic Aphasia: Identification of Predictive Biomarke… Not authorised

2024-518763-35-00 Chronic post-stroke aphasia.
A Multicentre, Randomised, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Efficacy and Safety of Dirocaftor/Posenacaftor/… Not authorised

2022-500410-26-00 Cystic Fibrosis
ABTECT-1 – ABX464 Treatment Evaluation for ulcerative Colitis Therapy -1 Not authorised

2022-500535-36-00 Moderately to severely active ulcerative colitis
ABTECT-2 – ABX464 Treatment Evaluation for ulcerative Colitis Therapy -2 Not authorised

2022-500536-11-00 Moderately to severely active ulcerative colitis
ABTECT-Maintenance – ABX464 Treatment Evaluation for ulcerative Colitis Therapy Not authorised

2022-500537-84-00 Moderately to severely active ulcerative colitis
An European multinational study of a personalized approach of human albumin administration in patients with cirrhosis of the liver and compl… Not authorised

2022-501006-34-00 Liver cirrhosis
A phase III, randomised, double-blind, multicentre study comparing the efficacy, safety, and immunogenicity of proposed tocilizumab biosimil… Not authorised

2022-501361-44-00 Adult patients of either gender with active moderate to
Clinical trial of MK-7648A in adults and children with skin cancer Not authorised

2022-501417-31-00 High-risk Resected Melanoma
Phase 3 Study Assessing Rocatinlimab (AMG 451) in Adolescent Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Orbit) Not authorised

2022-501535-16-00 Atopic Dermatitis (AD)
A Phase 3, Randomized Study to Compare Nemtabrutinib Versus Comparator (Investigator’s Choice of Ibrutinib or Acalabrutinib) in Participants… Not authorised

2022-501697-19-00 Small Lymphocytic Lymphoma (SLL) / Untreated Chronic Ly
A Phase IIIb, Single Arm, Open-label, Multicentre Study of Durvalumab in Combination with Chemotherapy for the First Line Treatment for Pati… Not authorised

2022-502043-35-00 Advanced Biliary Tract Cancers
A clinical study of people with HIV‐1 who switch their treatment to a combination of doravirine and islatravir Not authorised

2022-502079-49-00 HIV-1 infection
A clinical study of people with HIV-1 who have not taken antiretroviral therapy, one group will start treatment with a combination of doravi… Not authorised

2022-502099-22-00 HIV-1 Infection
A clinical study of people with HIV-1 who received prior treatment combination of doravirine and islatravir Not authorised

2022-502126-40-00 HIV-1 infection
A clinical study of people with HIV-1 who take antiretroviral therapy and switch their treatment to a combination of doravirine and islatrav… Not authorised

2022-502127-22-00 HIV-1 Infection
A randomised, controlled trial to investigate the effect of a four/six week intensified pharmacological treatment for schizophrenia, major d… Not authorised

2022-502185-24-00 Schizophrenia, schizoaffective disorder, schizophrenifo
MK-0616-013 Not authorised

2022-502777-42-00 Hypercholesterolemia
A study to investigate long-term safety and tolerability of tolebrutinib in participants with multiple sclerosis Not authorised

2023-503631-18-00 Nervous system diseases
Efepoetin alfa for treatment of anemia in chronic kidney disease on dialysis Not authorised

2023-503634-50-00 Anemia in patients with chronic kidney disease on dialy
A 52-week Clinical Trial to Study the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3) Not authorised

2023-503693-20-00 Severe eosinophilic asthma
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Plitidepsin in Adults with Post COVID-1… Not authorised

2023-504087-42-00 Post COVID-19
A prospective, observer-blind, randomized clinical trial to investigate and compare the clinical efficacy of Chloroprocaine 3% gel and Oxybu… Not authorised

2023-504477-21-00 male/female outpatients, aged 0-17 years scheduled to u