Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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Assessment of Flecainide to Lower the patent foramen Ovale closure risk of Atrial arrhythmia or Tachycardia Ended

2024-513324-42-00 Patent Foramen Ovale Closure Atrial Arrhytmia or Tachy 2022-03-23
Extension Study to Evaluate the Long-Term Outcomes of Paediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe… Ended

2024-513231-24-00 Retinopathy of prematurity (ROP) 2022-03-22
A Multi-Center, Randomized, Double-Blinded Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 versus Placebo in Adu… Ended

2024-514619-88-00 Relapsing Multiple Sclerosis 2022-03-18
Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer Ended

2023-506771-10-00 Breast Neoplasm, Neoplasm Metastasis 2022-03-11
Master Protocol for Avelumab Continuation Study. Ended

2023-509466-38-00 Cancer 2022-03-08
A study of Sacituzumab Govitecan Versus Docetaxel in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC). Ended

2024-512148-50-00 Non-small cell lung cancer 2022-03-03
A Multi-Center, Randomized, Double-Blinded Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 versus Placebo in Adu… Ended

2024-514618-11-00 Relapsing Multiple Sclerosis 2022-03-01
Single-cell deep phenotyping of B lymphocytes to personalize immunotherapy in patients with Myasthenia Gravis: clinical trial to evaluate th… Ended

2024-518939-12-00 Generalized Myasthenia Gravis 2022-02-28
A Randomized Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults … Ended

2023-503640-14-00 Newly diagnosed Philadelphia-negative B-cell precursor 2022-02-17
Assessment of effectiveness and safety of luspatercept in patients suffering from lower-risk myelodysplastic syndrome. Ended

2024-515069-33-00 Patients with anemia due to IPSS-R defined very low-, l 2022-02-15
A study of lurbinectedin in combination with atezolizumab compared with atezolizumab as maintenance therapy in participants with extensive-s… Ended

2023-503868-16-00 Small-Cell Lung Cancer (SCLC) 2022-02-14
An Open-Label Extension and Safety Monitoring Study of Acoramidis(AG10) in Participants with Symptomatic Transthyretin Amyloid Cardiomyopath… Ended

2024-515092-36-00 Symptomatic Transthyretin Amyloid Cardiomyopathy (ATTR- 2022-02-14
A study of tucatinib versus placebo in combination with pertuzumab and trastuzumab for subjects with advanced or metastatic HER2+ breast can… Ended

2023-503826-37-00 Unresectable locally-advanced or metastatic HER2+ breas 2022-02-11
A Study to Evaluate Safety and Efficacy of Ocrelizumab in Comparison with Fingolimod in Children and Adolescents with Relapsing-Remitting Mu… Ended

2023-506516-40-00 Relapsing-Remitting Multiple Sclerosis 2022-02-11
A Study to Evaluate the Efficacy and Safety of BIIB059 in Adult Participants With Active Systemic Lupus Erythematosus Receiving Background N… Ended

2023-505696-74-00 systemic lupus erythematosus 2022-02-10
Effects of calcium electroporation, electrochemotherapy, and irreversible electroporation (IRE-CaCl2, ECT and IRE) on quality of life and pr… Ended

2024-512487-61-00 Unresectable pancreatic cancer 2022-02-10
A study to learn how well finerenone works; how safe it is; how it moves into, through, and out of the body; and the effects it has on the b… Ended

2023-504884-17-00 Proteinuria 2022-02-04
Clinical trial to compare selinexor pomalidomide dexamethasone combination with elotuzumab pomalidomide dexamethasone in multiple myeloma pa… Ended

2024-518304-53-00 Relapsed or Refractory Multiple Myeloma (RRMM) 2022-02-02
Study to Evaluate the Safety, Tolerability, and Efficacy of 2000 mg/kg of Trappsol® Cyclo™ and Standard of Care Compared to Placebo and Stan… Ended

2024-518266-27-00 Niemann Pick Disease Type C1 2022-02-02
Efficacy and safety of remibrutinib compared to teriflunomide in participants with relapsing multiple sclerosis, followed by long term treat… Ended

2023-509372-41-00 Multiple Sclerosis 2022-01-30
Lutetium after second-line hormonal treatment [PBP-301] [SPLASH] Ended

2024-515604-39-00 Metastatic castration-resistant prostate cancer (mCRPC) 2022-01-28
Clinical trial of statins CAncer preventive and Pleiotropic TherApy IN smokers with chronic obstructive pulmonary disease (COPD) Ended

2024-516714-37-00 Chronic obstructive pulmonary disease (COPD) 2022-01-19
A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Inoperable or Metastatic Hormone Receptor-positive, HER2-negative Breast Ca… Ended

2023-509631-37-00 "Inoperable or Metastatic Hormone Receptor-Positive, HE 2022-01-18
Is there a survival benefit of administering thoracic radiotherapy concurrently with immunnotherapy and chemotherapy for patients with exten… Ended

2023-505514-15-00 Small-cell lung cancer, extensive stage 2022-01-11