Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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Efficacy of Tocilizumab in association to steroids in giant cell arteritis with cerebro-vascular involvement patients (ToGiAS). A french pro… Ended

2024-511906-21-00 Giant cell arteritis with Cerebro-vascular involvement 2021-09-24
A clinical study of OPT-302 with ranibizumab compared to ranibizumab alone in patients with neovascular age-related macular degeneration Ended

2024-512879-13-00 Neovascular age-related macular degeneration (wet AMD) 2021-09-23
A Randomized, Open-Label Trial to Compare Tisotumab Vedotin to Investigator's Choice Chemotherapy in Patients with Cervical Cancer Ended

2023-503813-31-01 Second- or Third-Line Recurrent or Metastatic Cervical 2021-09-17
Re-purposing of 2 well-known molecules (ketamine and magnesium sulfate) to treat a specific and excruciating type of pain (chronic cluster h… Ended

2024-518943-38-00 refractory chronic cluster headache 2021-09-15
A continuation study to evaluate the prophylactic and on demand treatment of congenital Thrombotic Thrombocytopenic Purpura (cTTP) with the … Ended

2024-513839-24-00 Congenital Thrombotic thrombocytopenic purpura (cTTP) 2021-09-07
A clinical study of OPT-302 with aflibercept compared to aflibercept alone in patients with neovascular age-related macular degeneration Ended

2024-512880-30-00 Neovascular Age-related Macular Degeneration (wet AMD) 2021-08-27
Phase 3 Open label clinical trial with oral Atogepant for the prevention of migraine Ended

2023-507096-21-00 Chronic or Episodic Migraine (Migraine without aura, mi 2021-08-16
A Study of Subcutaneous Risankizumab Injection for Pediatric Participants With Moderate to Severe Plaque Psoriasis to Assess Change in Disea… Ended

2023-504156-10-00 Plaque Psoriasis. 2021-08-13
Study to Evaluate the Safety and Efficacy of Paltusotine in Subjects with Acromegaly Ended

2024-511925-71-00 Acromegaly 2021-08-05
Dual Antithrombotic Therapy with Dabigatran and Ticagrelor in Patients with Acute Coronary Syndrome and Non-valvular Atrial Fibrillation Und… Ended

2024-515056-20-00 Acute Coronary Syndrome and Non-valvular Atrial Fibrill 2021-07-31
A study of GSK3511294 (Depemokimab) in participants who were previously enrolled in 206713 or 213744; Open-Label Extension Ended

2023-505203-23-01 Severe asthma with an eosinophilic phenotype 2021-07-26
Study of efficacy and tolerability of ofatumumab vs. First Line disease modifying treatment (DMT) - physician’s choice in the treatment of n… Ended

2023-507431-37-00 relapsing multiple sclerosis (RMS) 2021-07-23
Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal … Ended

2022-501342-29-00 Esophageal Carcinoma 2021-07-21
A phase III trial of trastuzumab + ALpelisib +/- fulvestrant versus trastuzumab + chemotherapy in patients with PIK3CA mutated previously tr… Ended

2024-514611-98-00 PIK3CA mutated HER2+ advanced or relapsed breast cancer 2021-07-20
A research study investigating troriluzole as a possible treatment for Obsessive Compulsive Disorder Ended

2024-514585-39-00 Obsessive Compulsive Disorder 2021-07-12
Metoprolol Safety and Efficacy in the Prevention of Cardiomyopathy in Patients with Duchenne Muscular Dystrophy (DMD) Ended

2024-515057-19-00 Duchenne muscular dystrophy; Cardiomyopathy; Tachycardi 2021-07-12
Eptinezumab as Preventive Treatment of Migraine in Adults with Migraine Ended

2023-510183-12-00 Chronic migraine 2021-07-05
Lighthouse II study Ended

2024-517054-94-00 AMYOTROPHIC LATERAL SCLEROSIS 2021-07-05
A Randomized Open-Label Phase III Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Subjects With Metastatic or Local… Ended

2024-513870-23-00 Locally Advanced or Metastatic Unresectable Urothelial 2021-06-28
An extension study to learn if Bimekizumab is safe and works as a long-term therapy in adults with moderate to severe hidradenitis suppurati… Ended

2024-511035-10-00 Hidradenitis Suppurativa 2021-06-23
The efficacy and safety of two doses of CHF6001 DPI as add-on to maintenance COPD triple therapy Ended

2023-510174-13-00 Chronic Obstructive Pulmonary Disease (COPD) 2021-06-17
The efficacy and the safety of two doses of CHF6001 for the treatment of Chronic Obstructive Pulmonary Disease (COPD) Ended

2023-510175-60-00 Chronic obstructive pulmonary disease (COPD) and Chron 2021-06-16
Long-term safety and efficacy of CSL312 (garadacimab) in the prophylactic treatment of hereditary angioedema attacks Ended

2024-510777-18-00 Hereditary angioedema 2021-06-15
EASE SBS 3 (Evaluation of the efficacy and safety of Glepaglutide in the treatment of short bowel syndrome (SBS) Ended

2024-513373-43-00 Short bowel syndrome 2021-06-11