Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Advanced Melanoma Ended

2024-511996-13-00 Previously untreated, unresectable, or metastatic melan 2022-05-11
A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multi-center, Phase III Study to Evaluate the Efficacy and Safety of Baricit… Ended

2024-518556-22-00 polymyalgia rheumatica 2022-05-10
An Open-label Extension Study of ARGX-113-2009 to Evaluate the Long-term Safety, Tolerability, and Efficacy of Efgartigimod PH20 SC in Adult… Ended

2024-515832-59-00 Bullous Pemphigoid 2022-05-03
This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study where subjects with non-pharmacologically treated acromeg… Ended

2024-511924-15-00 Acromegaly 2022-04-29
A prospective interventional randomized controlled trial to assess the effect of low dose acetylsalicylic acid as a preventive treatment of … Ended

2024-516816-72-00 preeclampsia 2022-04-27
A study comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF5993 With the Fixed Dose Dual Combination CHF153… Ended

2023-510172-31-00 Chronic obstructive pulmonary disease (COPD) 2022-04-22
"A PHASE 3, MULTICENTER, MULTINATIONAL, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY OF CC-93538 IN ADULT AND ADOLESCENT SUBJ… Ended

2023-506278-10-00 Eosinophilic esophagitis 2022-04-22
Study in highly sensitised kidney transplant patients with a high degree of antibodies against the donor's kidney to see the efficacy and sa… Ended

2024-511810-18-00 End stage chronic kidney disease (CKD) patients who are 2022-04-19
A Phase 3, randomized, double-blind, placebo-controlled, multicenter study of IV FDY-5301 in patients with a myocardial infarction (STEMI) Ended

2024-514372-40-00 Anterior ST-Elevation Myocardial Infarction 2022-04-12
Open-label extesnion study of soticlestat in Dravet and Lennox-Gastaut Syndromes Ended

2022-502802-34-00 Dravet and Lennox-Gastaut Syndromes 2022-04-05
A study to evaluate Sotatercept in Participants with PAH WHO FC III or FC IV at High Risk of Mortality Ended

2023-509140-10-00 Pulmonary Arterial Hypertension (PAH) 2022-04-05
A Phase 3, Randomized, Placebo-Controlled, Double-Blinded, Multicenter Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patient… Ended

2024-514130-20-00 complement 3 glomerulopathy (C3G)/immune complex membr 2022-04-04
A study to evaluate long-term safety of nintedanib in children and adolescents with interstitial lung disease (InPedILD®-ON) Ended

2024-515743-27-00 Childhood Interstitial Lung Disease 2022-04-04
Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Subjects 2 Years and Older Ended

2024-515606-90-00 Cystic Fibrosis 2022-04-01
A study to test long-term safety of Iclepertin in people with schizophrenia who took part in a previous CONNEX study Ended

2024-511560-93-00 Schizophrenia 2022-03-29
A Study to Investigate the Pharmacokinetics, Pharmacodynamics, Safety and Radiological and Clinical Effects of Subcutaneous (SC) Ocrelizumab… Ended

2023-505975-54-00 Multiple Sclerosis (MS) 2022-03-28
Advanced hormone receptor-positive/HER2-negative/HER2-Enriched breast cancer Ended

2023-508828-35-01 Patients with advanced hormone receptor-positive/HER2- 2022-03-28
Sotorasib and Panitumumab Versus Investigator’s Choice for Subjects with KRAS p.G12C Mutation (CodeBreaK 300) Ended

2024-511187-81-00 Colorectal Cancer (CRC) 2022-03-28
AcTIVE - ACid tranexamic or Terlipressin for Initial emergency treatment of mild to seVere hEmoptysis: a randomized Trial Ended

2024-515010-40-00 Hemoptysis, whatever the cause, with the exception of c 2022-03-28
A Phase 3 Study to Evaluate the Efficacy and Safety of ARO-APOC3 in Adults with Familial Chylomicronemia Syndrome Ended

2024-514336-24-00 Familial Chylomicronemia Syndrome (FCS) 2022-03-24
Efficacy and Safety of Budesonide and Formoterol Fumarate Metered Dose Inhaler in Patients with Inadequately Controlled Asthma Ended

2024-513568-24-00 Inadequately Controlled Asthma 2022-03-23
Study of Pembrolizumab/Vibostolimab Coformulation (MK-7684A) in Combination with Chemotherapy Versus Pembrolizumab Plus Chemotherapy as Fir… Ended

2023-506074-12-00 Metastatic Non-Small Cell Lung Cancer 2022-03-22
A clinical study to investigate if the investigational drug Diamyd is safe and can preserve insulin production and secretion in adolescents … Ended

2024-513304-33-00 Type 1 diabetes mellitus 2022-03-17
Long-term Safety Study of Adjunctive Troriluzole in Subjects with Obsessive Compulsive Disorder Ended

2024-512108-20-00 Obsessive Compulsive Disorder 2022-03-16