Phase I – Other

1,064 trials 249 recruiting

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ADP-A2M4CD8 in advanced cancers Ended

2024-512864-71-00 Urothelial cancer Esophageal cancer Gastric cancer Non 2020-05-27
Study of U3-1402 in subjects with non-small cell lung cancer Ended

2024-511205-33-00 METASTATIC OR UNRESECTABLE NON-SMALL CELL LUNG CANCER 2020-05-18
A phase 1 study of GSK2857916 + Standard of Care (SOC) in first line multiple myeloma patients (DREAMM-9) Ended

2023-507060-39-00 Multiple Myeloma 2020-03-04
A Phase 1b Study of Subcutaneous Daratumumab Regimens in Combination with Bispecific T Cell Redirection Antibodies for the Treatment of Subj… Ended

2023-503468-17-00 Multiple myeloma 2020-03-02
Trastuzumab Deruxtecan, and pembrolizumab in participants with Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer Ended

2023-509866-39-00 Locally advanced/metastatic breast or non-small cell lu 2020-02-14
Rollover study for continued safety and tolerability in subjects treated with spartalizumab alone or in combination with other study treatme… Ended

2023-508841-42-00 Different types of advanced cancer 2019-10-30
A Study Evaluating the Safety, Pharmacokinetics, and Activity of GDC-9545 Alone or in Combination with Palbociclib and/or LHRH Agonist in Pa… Ended

2023-506700-12-00 Locally Advanced or Metastatic Estrogen Receptor−Positi 2018-06-18
A Phase 1b Dose Escalation Study of Cabozantinib (XL184) Administered Alone or in Combination with Atezolizumab to Subjects with Locally Adv… Ended

2024-516477-73-00 Bladder cancer and kidney cancer 2018-03-07
„INSIGHT“ An explorative, open-labeled, phase I trial to evaluate feasibility and safety of eftilagimod alpha (IMP321, a LAG-3Ig fusion prot… Ended

2024-516026-56-00 Histologically confirmed locally advanced or metastatic 2017-08-17
A Phase 1 study to test the safety of an oral investigational drug (either AG-120 or AG-221) in combination with standard chemotherapeutic … Ended

2024-511380-29-00 Newly Diagnosed Acute Myeloid Leukemia with an IDH1 and 2015-12-16
A clinical study to evaluate the efficacy of ceritinib in combination with nivolumab in patients with ALK positive lung cancer Ended

2024-510824-38-00 Non-small cell lung cancer 2015-05-27
An Open-label Study to check Safety, Tolerability and medication behaviour of a capsule with AZD6244 in Patients with Advanced Solid Maligna… Ended

2022-500685-10-00 Advanced solid malignancies 2007-02-28
A Double-blind, Placebo-controlled, Multiple-Dose, 2-Period Crossover Study to Evaluate the Effect of Steady-state AZD6793 on the Steady-sta… Halted

2025-522551-25-00 Type 2 Diabetes Mellitus 2026-01-14
Phase 1b Study of Tarlatamab in Combination with YL201 with or without Anti-PD-L1 in Subjects with Extensive Stage Small Cell Lung Cancer (D… Halted

2024-515903-21-00 Extensive Stage Small Cell Lung Cancer (ES-SCLC) 2025-10-31
A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors Halted

2024-516916-93-00 This study will be a Phase 1b, global, multicenter, ope 2025-09-08
Methotrexate PK (in combination with Novobiocin) in RA patients Halted

2025-522531-34-00 Rheumatoid arthritis 2025-08-19
A study to test different doses of BI 765049 in people with advanced cancer of the colon, rectum, stomach, or pancreas Halted

2024-519301-36-00 colorectal carcinoma (CRC) 2025-07-11
Research into the effects of the drug DMT in healthy volunteers Halted

2025-521605-40-00 major depressive disorder (MDD) 2025-06-10
A Phase 1b Study of Neoadjuvant Xaluritamig in Subjects With Newly Diagnosed Localized Intermediate or High-Risk Prostate Cancer Halted

2024-511965-13-00 Newly diagnosed localized Intermediate or High‐Risk Pro 2024-11-25
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinet… Halted

2024-514744-91-00 Obesity/overweight (healthy subjects) 2024-09-16
A Phase 1 Study of CD19-targeted NEX-T CAR T Cells in Participants with RMS, PMS, or MG(Breakfree-2) Halted

2023-507820-22-00 Myasthenia gravis (MG) 2024-05-22
A Phase 1 Study of CD19-targeted NEX-T CAR T Cells in Participants with Severe, Refractory Autoimmune Diseases (Breakfree-1) Halted

2023-503823-24-01 Systemic Sclerosis 2024-04-15
Evaluation of tolerance and pharmacokinetics profile of high dose favipiravir in healthy volunteers - FAVIDOSE Halted

2022-502871-49-00 healthy volunteers 2024-04-05
A Phase 1, Double-blind, Randomized, Three-arm, Parallel Group Study to Compare the Pharmacokinetics and Safety of a Single Subcutaneous Dos… Halted

2024-519145-30-00 Healthy volunteers 2022-03-31