Phase I – Other

1,064 trials 249 recruiting

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A study in healthy people to compare how 2 different formulations of survodutide are taken up by the body Ended

2025-522325-35-00 Healthy volunteer trial 2025-10-27
An exploratory study to investigate the impact on the viral reservoir of adding a broadly neutralizing antibody with or without an attachmen… Ended

2025-520629-19-00 HIV Infections 2025-10-01
A Phase 1, Multicenter, Open-Label Study of REM-422, an MYB mRNA Degrader, in Patients With Relapsed/Refractory AML or Higher-Risk MDS Ended

2023-510479-72-00 Relapsed/Refractory AML or Higher-Risk MDS 2025-08-05
A clinical study to investigate the antibacterial efficacy of arbutin metabolites in urine. Ended

2024-519011-34-00 Urinary Tract Infection 2025-08-04
Evaluation of the efficacy and safety of drug treatment in familial polycythemia associated with an EPO gene mutation: a multicentre, open-l… Ended

2025-521906-16-00 familial polycythemia associated with an EPO gene mutat 2025-08-01
A Single-Dose Pharmacokinetic Study of Lepodisiran in Participants with Varying Degrees of Liver Impairment and Participants with Normal Liv… Ended

2024-520315-40-00 Normal Hepatic Function and Mild, Moderate, or Severe H 2025-07-22
A PHASE 1B, OPEN-LABEL, DOSE ESCALATION WITH AN EXPANSION TRIAL OF A IN COMBINATION WITH B OR A PLUS STANDARD OF CARE IN PATIENTS WITH XXX C… Ended

2025-521582-27-00 XXX CANCER ELIGIBLE FOR SECOND LINE TREATMENT 2025-07-03
A study to see the effect of NNC0194-0499 alone or in combination with semaglutide on blood sugar control in people living with type 1 diabe… Ended

2024-519533-38-00 Diabetes mellitus type 1 2025-06-24
A Phase 1 open-label positron emission tomography TRIAL to assess changes in liver uptake of [68Ga]Ga-FAPI-46 following oral administration … Ended

2024-517605-91-00 advanced liver fibrosis 2025-05-26
A Study to Learn How the Study Medicine Called PF-07868489 is Tolerated and Acts in Healthy Adult People and People With Pulmonary Arterial … Ended

2024-514064-17-00 Pulmonary Arterial Hypertension 2025-05-23
A Double-Blind, Randomized, Placebo-Controlled, Phase 1b Study to Assess the Safety, Tolerability, and Pharmacokinetics of Multiple Ascendin… Ended

2024-519899-72-00 Alzheimer's Disease 2025-05-08
"A study to test how well BI 3000202 is tolerated by people with type 1 interferonopathies" Ended

2024-514942-35-00 Type 1 interferonopathies 2025-04-11
AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protoco… Ended

2024-511253-21-00 Thoracic tumors with homozygous MTAP-deletion 2025-02-28
Study of EGF816 in combination with selected targeted agents in EGFR-mutant NSCLC. Ended

2024-511757-21-00 Patients with EGFR-mutant Non Small Cell Lung Cancer 2024-12-20
A Phase 1b Study of JNJ-80948543 in Combination with Other CD3 TCEs for R/R B-cell NHL Ended

2024-514176-41-00 Relapsed/Refractory B-cell Non-Hodgkin Lymphoid Maligna 2024-12-16
M9466 Alone or in Combination in Advanced Solid Tumors (DDRiver 501) Ended

2024-513492-41-00 Advanced solid tumors 2024-11-19
Phase I trial with 177Lu-DOTA-TATE and olaparib in somatostatin receptor positive tumours Ended

2024-512463-31-00 Somatostatin receptor positive tumours 2024-10-27
A phase Ib, open-label, ascending dose study with step-up doses to assess safety, tolerability, and pharmacokinetics of PIT565 in participan… Ended

2023-510025-14-00 Systemic Lupus Erythematosus 2024-10-08
AMG 193 in Combination with Other Therapies in Subjects with Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous… Ended

2024-511195-33-00 Gastrointestinal tract, biliary tract, or pancreatic ca 2024-09-23
Linfociti T virus-specifici per infezioni virali resistenti alla terapia farmacologica dopo trapianto allogenico di cellule staminali emopoi… Ended

2024-518925-14-02 Patients who have received an allogeneic haematopoietic 2024-07-17
A study to learn the effects of ripretinib (study drug) on how midazolam behaves in the body of people with advanced gastrointestinal stroma… Ended

2022-501477-40-00 Advanced Gastrointestinal Stromal Tumor 2024-06-25
Effect of nucleoside reverse transcriptase inhibitors on innate immune priming Ended

2023-510378-14-00 modulation of the innate immune system in healthy subje 2024-06-20
A Phase 1 Randomized, Open Label Pharmacokinetic Comparability Study Comparing Pre- and Post-change Teclistamab in Participants with Relapse… Ended

2023-508426-10-00 Relapsed/Refractory Multiple Myeloma 2024-06-03
Phase Ib Dose Finding Study of [177Lu]Lu-NeoB in Combination with RT and TMZ in Newly Diagnosed Glioblastoma and as a Single Agent in Recurr… Ended

2022-502134-10-00 Glioblastoma 2024-05-15