Respiratory Tract Diseases

568 trials 207 recruiting

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The NeoTRACK Trial – Neoadjuvant TiRagolumab, Atezolizumab and Chemotherapy – Dissection of IO efficacy in NSCLC by longitudinal tracKing: a… Halted

2022-501322-38-00 Non-small cell lung cancer (NSCLC) 4 2023-05-26
A Trial to Determine if Quabodepistat is Processed Differently in Adults with Reduced Liver Function Compared to Adults with Normal Liver Fu… Ended

2025-521502-18-00 Tuberculosis 3 2025-11-13
Phase 2b Randomized, Double-Blind Study with Phage for CF Subjects with Pseudomonas Lung Infection Ended

2024-519856-94-00 Cystic fibrosis 4 2025-08-18
Cardiovascular safety assessment of Tanimilast in healthy volunteers Ended

2024-516861-35-00 This is Phase I study to assess the effect on the heart 3 2025-07-31
A randomized, single dose, cross-over, replicated, open-label bioequivalence study comparing indacaterol/glycopyrronium (85/43mcg inhalation… Ended

2024-514725-38-00 Maintenance bronchodilator treatment to relieve symptom 2 2025-05-26
A randomised, open-label, 5-period, cross-over trial to assess the pharmacokinetics and safety of 3 oral solid formulations of buloxibutid (… Ended

2025-520702-35-00 Idiopahtic pulmonary fibrosis 3 2025-05-14
An Accessorised Prefilled Syringe to an Autoinjector Pharmacokinetic Bridging Study of Tozorakimab Ended

2024-511840-22-00 Inflammation 3 2025-04-22
Phase I single-blind clinical trial to evaluate the safety and local immune activation of a toll-like receptor 5 agonist (FLAMOD) administer… Ended

2024-515933-14-00 Pneumonia 1 2025-04-14
A comparison study between adolescents with asthma and adults with asthma on how they absorb, metabolise and eliminate CHF 6001 Ended

2024-516483-29-00 Asthma 4 2025-03-24
Open-label, non-randomised, single-dose, one sequence, two-period, cross-over study to investigate the effect of inhibition of P-glycoprotei… Ended

2024-516475-32-00 Chronic obstructive pulmonary disease 3 2025-03-17
Not applicable Ended

2024-518150-17-00 Non-cystic fibrosis bronchiectasis 3 2025-03-10
A proof-of-concept study of lunsekimig compared with placebo in adults with chronic rhinosinusitis with nasal polyps Ended

2024-511261-11-00 Respiratory tract diseases 4 2025-03-05
A randomised, double-blind, placebo-controlled trial to assess the effects of EP395 following an inhaled endotoxin challenge in healthy adul… Ended

2024-516187-29-00 Healthy volunteers [targeted indication: chronic obstru 3 2025-02-20
A Phase Ib, Multicentre, Randomised, Single-blind, Parallel-group, Placebo-controlled, Study to Characterise the Pharmacokinetics and Pharma… Ended

2024-516474-30-00 Asthma 3 2025-02-19
Study evaluating the efficacy of the treatment after targeting PD-L1 and TIGIT in tumors with tertiary lymphoid structures Ended

2023-503218-56-00 Adult patients with a histologically confirmed TLS-posi 4 2025-01-30
A Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of AZD8630, Administered Once Daily via Inhalation, for 2 Weeks, in Adu… Ended

2024-514213-35-00 Asthma 3 2025-01-20
Ceftobiprole OATP1B interaction study Ended

2024-518592-60-00 Community-acquired bacterial pneumonia 3 2025-01-17
A study to test how well BI 3720931 is tolerated and whether it improves lung function in people with cystic fibrosis (LenticlairTM 1) Ended

2023-503281-23-00 Cystic fibrosis 7 2024-12-19
Evaluation of safety, side effects and how the inhaled drug CHF10073 is absorbed, modified and removed from the body when administered alone… Ended

2024-515442-17-00 Pulmonary fibrosis 1 2024-12-03
TURN-COVID Biobank: The Dutch cohort study for the evaluation of the use of neutralizing monoclonal antibodies and other antiviral agents ag… Ended

2024-515263-60-00 SARS-CoV-2 infection 6 2024-11-22
Evaluation of the CHF 5993 concentration in blood, after inhalation with two different devices, (NEXThaler® versus pMDI), with and without A… Ended

2024-512792-13-00 Asthma 3 2024-11-13
A study on the safety of and immune response to different doses of an mRNA vaccine against RSV in healthy adults. Ended

2024-512846-41-00 Respiratory Syncytial Virus Infections 1 2024-11-12
A randomized, open-label, controlled phase III trial comparing the pembrolizumab platinum based chemotherapy combination with pembrolizumab … Ended

2024-513697-22-00 non-small-cell lung cancer 5 2024-11-07
A Phase 1/2a Study Evaluating the Effects of ARO-MMP7 Inhalation Solution in Healthy Subjects and Patients with Idiopathic Pulmonary Fibrosi… Ended

2023-504964-41-00 Idiopathic pulmonary fibrosis 7 2024-11-06