Respiratory Tract Diseases

589 trials 200 recruiting

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An Open-Label Extension to Study the Long-Term Effect of Dexpramipexole in Participants with Severe Eosinophilic Asthma (EXHALE-5) Under evaluation

2024-510810-33-00 Severe eosinophilic asthma 5 2024-10-14
A study to assess the efficacy and safety of OATD-01 for the treatment of active pulmonary sarcoidosis. Not authorised

2023-506642-23-00 Active Pulmonary Sarcoidosis 4
A randomized, double-blind, placebo-controlled clinical endpoint bioequivalence study to evaluate the therapeutic equivalence and safety of … Not authorised

2025-521565-27-00 Asthma 5
Clinical trial to assess the safety and tolerability of TP-122A for the treatment of ventilator-associated pneumonia. Not authorised

2023-508825-29-00 Ventilator-Associated Pneumonia 7
A Multicentre, Randomised, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Efficacy and Safety of Dirocaftor/Posenacaftor/… Not authorised

2022-500410-26-00 Cystic Fibrosis 5
Randomized, multiCentre, dOuble-blind, double-duMmy, parallel-group clinical study on efficacy and safety of iBuprofen/N-acetylcysteine fixe… Not authorised

2023-505809-17-00 Upper respiratory tract infections 5
A two part, randomized, double-blind, placebo-controlled, parallel group SAD and MD clinical study to evaluate the safety, tolerability and … Not authorised

2022-503145-22-00 Pseudomonas colonization 1
"Efficacy and safety of Balanced Analgosedation in Bronchoscopy with Propofol/Pethidine versus Midazolam/Pethidine: a single-centre randomis… Not authorised

2024-518820-65-00 Bronchoscopic procedure with analgosedation for the dia 6
A 52-week Clinical Trial to Study the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3) Not authorised

2023-503693-20-00 Severe eosinophilic asthma 5
A RAndomised Placebo Controlled Trial - to Explore the Efficacy and Mechanism of Action of Tezepelumab in EGPA- RACE-MATE Not authorised

2024-514794-22-01 Eosinophilic granulomatosis with polyangiitis (EGPA) 4
A Study to Learn About the Safety, Tolerability and Blood Levels of a Study Medicine (called sisunatovir) in Infants and Children with RSV L… Not authorised

2023-504425-39-00 Respiratory Syncytial Virus (RSV) Infection 3
STOP-COPD Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease Not authorised

2022-500816-21-00 Acute Exacerbation of Chronic Obstructive Pulmonary Dis 6
A seamless, phase 1b/2 multiple ascending dose/proof of concept study of XTMAB-16 in patients with pulmonary sarcoidosis with or without ext… Not authorised

2022-502877-41-00 Pulmonary sarcoidosis with or without extrapulmonary ma 9
A double-dummy, double-blind, randomized, active controlled, two-way cross-over study with 12-week treatment duration per period, to evaluat… Pending

2022-502365-26-00 Asthma 5
Nebulized Amikacine for Ventilator associated gram negative Pneumonia in ECMO veno-arterial patients: A randomized Pilot Study (NAVAP-ECMO) Pending

2023-509722-22-00 gram-negative bacillus pneumonia acquired during mechan 4
A Study to Learn About the Study Medicine Called PF-07275315 in Adults with Moderate-To-Severe Long-Term Breathing Difficulty, Known by the… Pending

2024-518587-12-00 MODERATE-TO-SEVERE CHRONIC OBSTRUCTIVE PULMONARY DISEAS 4
Adding oxygen to enhance antibiotic treatment of chronic lung infection Pending

2024-513197-22-02 Primary ciliary dyskinesia 3
Double-blind randomized controlled study versus placebo to evaluate the efficacy of mono-administration of betamethasone in children with sy… Pending

2024-518095-31-00 Adenovirus infection 5
SPARE : Stopping Pneumonia Antibiotherapy Regimen Early Pending

2024-512236-30-00 Community-acquired alveolar pneumonia in children 5
Pilot randomized controlled trial of the prevention of early respiratory tract infections in intubated patients. Comparison of the safety an… Pending

2025-521454-42-00 Reduced level of consciousness associated with severe t 6
The effect of Oxygen sUppleTion on vascular resistance and FLOW: the OUTFLOW study Pending

2024-516279-34-00 Pulmonary Hypertension 6
A prospective, controlled, randomized, double blind, 2-arms, parallel-group, multicentre, phase 3 study to investigate effectiveness of Acti… Pending

2024-516284-90-00 rhinosinusitis not requiring antibiotic therapy 5
Efficacy and safety of anakinra in non-COVID-19 related ARDS. ESKA study. Pending

2024-518125-15-00 Acute respiratory distress syndrome (ARDS) 4
A Phase II study to investigate lung function with 2 different doses of inhaled glycopyrronium taken with BFF compared to BFF in participant… Pending

2025-524914-26-00 Asthma 4