Immune System Diseases

926 trials 377 recruiting

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A Phase 2a Multicenter, Randomized, Double Blind, Parallel, Proof of concept Study Evaluating the Efficacy and Safety of Nipocalimab and Cer… Ended

2023-504045-31-00 Rheumatoid Arthritis 4 2024-02-08
This study will use a new investigation study drug called OMS906 in peoplewith C3 Glomerulopathy (C3G) or Idiopathic Immune Complex-Mediated… Ended

2023-508669-33-00 C3 Glomerulopathy and Idiopathic Immune Complex-Mediate 4 2024-01-29
An open-label cocktail drug-drug interaction (DDI) clinical study to assess the effect of multiple oral dosing with leniolisib on the pharma… Ended

2023-507134-25-00 Activated Phosphoinositide 3-Kinase Delta Syndrome 3 2024-01-29
A Study to Learn How Different Manufactured Products of the Study Medicine Called Ritlecitinib are Taken up Into the Blood in Healthy Adults… Ended

2023-505603-23-00 ulcerative colitis, Crohn’s Disease, alopecia areata, r 3 2024-01-29
An open-label, single-dose, parallel-group study to evaluate the plasma pharmacokinetics of leniolisib in subjects with impaired hepatic fun… Ended

2023-508519-22-00 Activated Phosphoinositide 3-Kinase Delta Syndrome 3 2024-01-26
A phase IV, open, non-randomised, low-intervention clinical trial to evaluate the subjective user experience of Zeqmelit™ 6 mg mouth dissolv… Ended

2023-504975-25-00 Acute allergic reaction 11 2024-01-26
A study to evaluate efficacy and safety of SAR441566 in adults with plaque psoriasis Ended

2023-503911-14-00 Psoriasis 4 2024-01-25
A study to evaluate how the body absorbs, breaks down and removes drug as well as safety and tolerability when two drugs are administered to… Ended

2023-506580-34-00 Healthy Volunteers 3 2024-01-04
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants with Moderate-to-Severe Thy… Ended

2023-503669-50-00 Moderate-to-Severe Thyroid Eye Disease 5 2023-12-27
An open-label, cross-over, multi-site, prospective, phase IIb study of effects on circadian rhythms and quality of life of modifieddual-rele… Ended

2023-503584-42-00 Addison’s Disease 4 2023-12-22
A Phase 2 Multicenter Study to Evaluate PF-06823859 in Adult Participants With Active CLE or SLE With Cutaneous Manifestations Ended

2023-503343-33-00 Active Cutaneous Lupus Erythematosus (CLE) or Systemic 4 2023-12-21
A Sub Study to Learn About the Study Medication Called Etrasimod Tablets in a Hybrid Decentralized Clinical Trial Setting Ended

2023-508119-22-00 immune-mediated inflammatory disorders, including ulcer 3 2023-12-18
A study to learn if atrasentan is safe and works in people with IgA nephropathy who are taking an SGLT2i Ended

2023-503828-13-00 Nephrology 4 2023-12-12
A study to investigate the pharmacokinetics of remibrutinib in CSF in healthy participants. Ended

2023-506760-13-00 Healthy 3 2023-12-11
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants with Moderate-to-Severe Thy… Ended

2023-503309-13-00 Moderate-to-Severe Thyroid Eye Disease 5 2023-11-29
Tofacitinib in early active axial spondyloarthritis: a prospective, randomized, double-blind, placebo-controlled multicentre study - FASTLAN… Ended

2023-505050-18-00 Axial spondyloarthritis 6 2023-11-16
Orismilast for the treatment of moderate to severe ulcerative colitis Ended

2022-502763-37-02 ulcerative colitis 4 2023-11-16
A study to test the efficacy and safety of SAR442970 in adults with hidradenitis suppurativa Ended

2022-502370-17-00 Hidradenitis suppurativa 4 2023-11-14
Phase II-III study to assess the efficacy and safety of sublingual immunotherapy in patients suffering from grass pollen allergy Ended

2023-505880-35-00 Moderate-to-severe allergic rhinitis / rhinoconjunctivi 10 2023-11-10
An Open-Label, Phase 2, Safety, and Efficacy Study of Ruxolitinib Cream in Participants With Genital Vitiligo Ended

2023-503737-22-00 Nonsegmental vitiligo with genital involvement 4 2023-11-08
A trial to investigate the effect of acalabrutinib on skin prick test wheal size in adults with grass pollen allergy Ended

2023-505783-11-00 grass pollen allergy 3 2023-10-26
A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE) Ended

2022-502227-22-00 Autoimmune disease 4 2023-10-25
A study to investigate JNJ-80202135 (nipocalimab) delivered subcutaneously via prefilled syringe autoinjector and via normal syringe Ended

2023-504280-16-00 Healthy Volunteers 3 2023-10-17
Evaluation of Lymphodepletion With ALLO-647 in Adults With R/R Large B Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy (EXPA… Ended

2023-503830-27-00 Large B-Cell Lymphoma (LBCL) 4 2023-10-17