Digestive System Diseases

647 trials 308 recruiting

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metastatic colorectal cancer Recruiting

2023-504831-42-00 patient with colorectal cancer with hepatic metastasis 5 2025-06-27
A study to investigate efficacy and safety of SAR441566 in patients with ulcerative colitis Recruiting

2025-520705-12-00 Colitis Ulcerative 4 2025-06-24
BreAK CRC (001) trial Recruiting

2024-512011-45-00 Unresectable locally advanced or metastatic colorectal 7 2025-06-17
Nitroglycerin for Esophageal Food Impaction Recruiting

2023-503983-17-00 Esophageal Food Impaction 4 2025-06-12
Trial of Trastuzumab Deruxtecan (Enhertu®) Plus Chemotherapy Plus or Minus Pembrolizumab versus Chemotherapy Plus Trastuzumab Plus or Minus … Recruiting

2024-513122-27-00 Unresectable, Locally Advanced or Metastatic HER2 posit 5 2025-06-10
Evaluation of the effectiveness and safety of ALKACITRAT® on the treatment of functional dyspepsia Recruiting

2024-512688-30-00 Functional Dyspepsia 6 2025-06-04
Pilot Study of Liver Fibrosis Stage Assessment by Fibroblast Activation Protein Imaging in Patients With Biopsy for Suspected or Proven Nona… Recruiting

2024-511788-27-01 non-alcoholic hepatic steatosisalcoholic hepatic steato 4 2025-06-03
A Study to Compare the Efficacy and Safety of Vedolizumab With and Without Upadacitinib in Adults With Moderately to Severely Active Crohn's… Recruiting

2023-509391-42-00 Chron's Disease 11 2025-06-02
Evaluation of the efficacy and safety of dual biologic and/or small molecule therapy in patients with induction-resistant ulcerative colitis… Recruiting

2023-506628-98-00 Ulcerative colitis 4 2025-05-27
Does placement of a TAP block in patients undergoing laparoscopic inguinal hernia repair have a more efficacious analgesic effect than local… Recruiting

2024-515759-39-00 inguinal hernia 6 2025-05-13
Evaluation of the efficacy and safety of dual biological therapy in patients with refractory Crohn's disease resistant to induction (FLAMING… Recruiting

2023-506626-37-00 Crohn's disease 4 2025-04-18
Effect of Carvedilol on the portosystemic gradient as measured by endoscopic ultrasound Recruiting

2024-518302-41-00 cirrhotic portal hypertension 4 2025-04-16
A Study to Test the Effectiveness and Safety of RO7790121 for induction and maintenance therapy in Patients with Moderately to Severely Acti… Recruiting

2024-513053-69-00 Moderately to Severely Active Crohn's Disease (CD) 5 2025-04-16
Effect of low-dose arginine-vasopressin supplementation on post-transplant Acute Kidney Injury after liver transplantation - AVENIR Trial Recruiting

2023-506512-40-00 Acute Kidney Injury 5 2025-04-16
A Study to Assess the Effectiveness and Safety of Induction Therapy with RO7790121 in Participants with Moderately to Severely Active Crohn'… Recruiting

2024-513054-30-00 Moderately to Severely Active Crohn's Disease (CD) 5 2025-04-16
A study to investigate efficacy and safety of SAR441566 in patients with Crohn's disease. Recruiting

2024-512633-32-00 Crohn's disease 4 2025-04-07
EXPOSURE Study Recruiting

2024-513353-73-00 Porto-Sinusoidal Vascular Disorder 4 2025-04-04
Early Phase II Exploratory, Open-Label, Non-Randomized Study of Neoadjuvant Dostarlimab Monotherapy in Participants with Untreated T3-4N0-2 … Recruiting

2024-512499-36-00 pMMR/MSS resectable Colon Cancer 4 2025-04-03
Pre-Operative Treatment in rEseCTable cOlon canceR (PROTECTOR/FIRE-10; AIO-KRK-0620; IAG-VO-0323) Prospective, randomized, open-label, multi… Recruiting

2023-508076-11-00 Colon cancer staged T3-4 and/or nodal positive by CT an 5 2025-04-01
MAINTAIN-POP: EXL01 and prevention of post-operative recurrence of Crohn's disease Recruiting

2024-511357-22-00 Crohn's disease 4 2025-03-31
Efficacy and safety of bezafibrate 400 mg and bezafibrate 200 mg as adjunctive treatments in patients with primary biliary cholangitis and n… Recruiting

2023-504086-23-00 Subjects with PBC with a non-optimal response to UDCA. 5 2025-03-27
Comparison of ustekinumab, infliximab and COMBinatiOn therapy in moderately-to-severely active Ulcerative Colitis – the head-to-head COMBO-U… Recruiting

2023-506452-25-00 Ulcerative colitis 4 2025-03-27
HALT : Influence of Human Albumin supplementation on kidney dysfunction after Liver Transplantation Recruiting

2024-514804-14-00 Liver transplantation 6 2025-03-26
68-Ga-FAPI-46 positron emission tomography (PET) to better visualise pancreatic and bile duct cancer. Recruiting

2024-516486-36-00 cholangiocarcinoma (bile duct cancer) 10 2025-03-24