Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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BOTAF - Prevention of post-operative Atrial Fibrillation by BOTulinum toxin injections into epicardial fat pads around pulmonary veins in pa… Ended

2024-513645-37-00 Adult patients with indication for conventional cardiac 2024-09-05
A Study of Lepodisiran (LY3819469) in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a) Ended

2023-509190-23-00 Atherosclerotic Cardiovascular Disease Elevated lp(a) 2024-09-03
A Study of Subcutaneously Injected Epcoritamab Plus Oral Lenalidomide Capsules Compared to Intravenously (IV) Infused Rituximab Plus IV Infu… Ended

2024-510965-41-00 Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymph 2024-09-03
A study to investigate the safety and efficacy of fostemsavir in heavily treatment experienced people living with HIV-1 resistant to other d… Ended

2024-513930-39-00 Heavily Treatment Experienced Subjects Infected with Mu 2024-08-30
A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Patients with previously treated KRAS G12C-positive… Ended

2024-510908-37-00 KRAS G12C-Positive Advanced or Metastatic Non-Small Cel 2024-08-28
A Study of Mavacamten in Adolescent Participants with Symptomatic Obstructive Hypertrophic Cardiomyopathy Ended

2023-505650-17-00 Symptomatic Obstructive Hypertrophic Cardiomyopathy 2024-08-27
MLS-101-901: An Open-Label Extension Study to Assess the Long-Term Safety, Efficacy, and Tolerability of Lorundrostat in Subjects with Hyper… Ended

2023-508670-28-00 Hypertension 2024-08-26
Extension trial for adults with high cholesterol who completed a MK-0616 clinical trial Ended

2023-504922-20-00 Hypercholesterolemia 2024-08-23
Clinical trial to assess the efficacy and safety of a vaccine for grasses and olive tree allergy Ended

2024-514525-34-00 Aetiological treatment of moderate-severe intermitent o 2024-08-18
Comparison of an inhaled sedation strategy with an intravenous sedation strategy in intensive care patients treated with invasive mechanical… Ended

2024-513530-37-00 Delirium 2024-08-09
A clinical study of MK-2870 in people with stomach cancer (MK-2870-015) Ended

2023-505423-31-00 advanced or metastatic gastric adenocarcinoma, gastroes 2024-08-08
Phase 3 Study of ALXN1850 versus Placebo in Adolescent and Adult Participants with HPP who have not previously been treated with Asfotase Al… Ended

2023-505673-32-00 Hypophosphatasia 2024-08-05
Efficacy and safety of subcutaneous dupilumab in participants with asthma/asthmatic wheeze aged 2 to <6 years Ended

2023-504331-41-00 Respiratory tract diseases - Wheezing, Asthma 2024-08-02
ARTEMIS - A research study to look at how ziltivekimab works compared to placebo in people who have had a heart attack Ended

2023-506876-28-00 The medical condition we are investigating is type 1 AM 2024-08-01
An extension and crossover vaccination study on the immune response and safety of a vaccine against respiratory syncytial virus given to adu… Ended

2023-509762-38-00 Respiratory Syncytial Virus Infections 2024-08-01
A Study to Compare the Efficacy and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants with Previously Untreated High-… Ended

2023-510178-15-00 High-risk Large B-cell Lymphoma 2024-07-31
Comparison of targeted radiotherapy with and without short-term hormonal treatment (6 months) Ended

2024-511252-41-00 Patients with biochemical recurrence after primary trea 2024-07-30
A study to Evaluate the Efficacy and Safety of Mitapivat in Subjects With Transfusion-Dependent Alpha- or Beta-Thalassemia (ENERGIZE-T) Ended

2024-512747-23-00 Transfusion-Dependent Alpha- or Beta-Thalassemia 2024-07-30
Selective Treatment of Oral Povorcitinib in Hidradenitis Suppurativa Long-Term Extension Study (STOP-HS LTE) Ended

2023-507204-31-00 Hidradenitis Suppurativa 2024-07-26
A study to find how well Dazodalibep works and how safe it is in participants with Sjögren’s Syndrome Ended

2023-503923-24-00 Sjögren’s Syndrome With Moderate-toSevere Symptom State 2024-07-22
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of Oral NMRA-335140 versus Placebo in Participants wit… Ended

2023-506335-15-00 Major Depressive Disorder 2024-07-18
[18F]F-FAPI PET-CT to Identify Carcinoma of Unknown Primary origin Ended

2023-505592-69-00 Carcinoma of Unknown Primary 2024-07-12
An Open-label Extension Study Evaluating the Long-term Safety and Efficacy of Seralutinib Orally Inhaled for the Treatment of Pulmonary Arte… Ended

2023-506334-75-00 Pulmonary Arterial Hypertension 2024-07-12
Add-Aspirin: A phase III, double-blind, placebo controlled, randomised trial assessing the effects of aspirin on disease recurrence and surv… Ended

2024-511306-23-00 Breast cancer, colon cancer, rectal cancer, stomach can 2024-07-01