Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell L… Recruiting

2022-501489-24-00 First-line treatment of adult subjects with high-risk l 2025-03-28
A study in newly diagnosed glioblastoma patients that aims at testing the efficacy of Optune (Tumor Treating Fields), together with temozolo… Recruiting

2024-513550-30-00 Newly diagnosed Glioblastoma 2025-03-28
CHAPTER-4 – A long term trial of deucrictibant treatment in prophylaxis against HAE attacks in adults and adolescents Recruiting

2024-516248-24-00 Hereditary Angioedema 2025-03-28
PROTamine Application in patients underGOing tRAnScatheter aortic valve replacement (PROTAGORAS) Recruiting

2024-512024-10-01 Adult patients with severe aortic stenosis scheduled fo 2025-03-28
Gemcitabine plus nab-PAclitaxel as switch maiNTEnance versus cONtinuation of modified FOLFIRINOX as first-line chemotherapy in patients with… Recruiting

2024-515214-41-00 advanced pancreatic cancer 2025-03-27
Efficacy and safety of bezafibrate 400 mg and bezafibrate 200 mg as adjunctive treatments in patients with primary biliary cholangitis and n… Recruiting

2023-504086-23-00 Subjects with PBC with a non-optimal response to UDCA. 2025-03-27
PHASE III, DOUBLE-BLIND, RANDOMIZED, CONTROLLED, NON-INFERIORITY, PHASE III CLINICAL TRIAL TO EVALUATE THE EFFICACY OF SALBUTAMOL MONOTHERA… Recruiting

2024-514065-19-00 Acute asthma. Patients with moderate asthma attacks wil 2025-03-27
A study to investigate changes in symptoms in adult participants with chronic rhinosinusitis with nasal polyposis initiating treatment with … Recruiting

2024-513862-20-00 Chronic Rhinosinusitis with Nasal Polyposis 2025-03-26
A study to investigate the efficacy and safety of subcutaneous sonelokimab versus placebo and risankizumab (active reference arm) in partici… Recruiting

2024-516219-25-00 psoriatic arthritis 2025-03-25
Metal Panel Patch Test Recruiting

2023-507972-35-01 Allergic contact dermatitis 2025-03-24
Elacestrant versus Standard Endocrine Therapy in Women and Men with Node-positive, Estrogen Receptor-positive, HER2-negative, Early Breast C… Recruiting

2024-515445-42-00 Node-positive, Estrogen Receptor-positive, HER2-negativ 2025-03-24
PRESERVE-003: ONC-392 (Study Drug) Versus Docetaxel (Standard of Care) in Metastatic Non-small Cell Lung Cancer That Progressed on PD-1/PD-L… Recruiting

2023-505311-20-01 Metastatic Non-Small Cell Lung Cancer 2025-03-21
Mechanisms of action on rectal motility of intrarectal botulinum toxin injections in patients with fecal incontinence - MECA-TOX Recruiting

2024-515256-21-00 Fecal incontinence 2025-03-21
5% KOH solution vs placebo treatment of actinic keratosis with different treatment duration Recruiting

2024-514277-21-00 Actinic keratosis 2025-03-19
PostoperAtIve Oxygen suppLy to reduce tempOrary deSaturation in patients after non-cardiac surgery, a prospective, randomised controlled tri… Recruiting

2024-514285-39-00 risk for postoperative complications after general surg 2025-03-19
A clinical study of zilovertamab vedotin in people with large B-cell lymphoma (MK-2140-010) Recruiting

2024-515566-13-00 Diffuse Large B-Cell Lymphoma (DLBCL) 2025-03-19
A Phase 3 Efficacy and Safety Study of Pitolisant in Patients with Prader-Willi Syndrome Recruiting

2023-508307-21-00 Prader-Willi syndrome 2025-03-19
A study to measure how well seltorexant works in adult depressed patients and how safe it is both for short- and long-term use when taken wi… Recruiting

2023-509070-36-00 Major Depressive Disorder with Insomnia Symptoms 2025-03-18
An open-label extension study with dazukibart for participants with idiopathic inflammatory myopathies (including DM or PM) who have complet… Recruiting

2024-514648-10-00 Idiopathic Inflammatory Myopathy (including dermatomyos 2025-03-14
Study to evaluate efficacy and safety of inclisiran in children aged 6 to under 12 years of age with heterozygous familial hypercholesterole… Recruiting

2024-514594-21-00 Heterozygous Familial Hypercholesterolemia 2025-03-13
A study to learn if bimekizumab is safe and how it moves throughout the body in children with certain types of juvenile idiopathic arthritis Recruiting

2023-508845-41-00 Active juvenile idiopathic arthritis subtypes enthesiti 2025-03-11
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant Recruiting

2024-513547-82-00 Transthyretin Amyloidosis 2025-03-11
A study to assess the efficacy and safety of lumateperone in patients with major depressive disorder Recruiting

2023-503836-41-00 Major Depressive Disorder 2025-03-10
Thrombolysis in Factor Xa-inhibitors Trial (SIFT) Recruiting

2023-509907-34-01 acute ischemic stroke 2025-03-10